Staff View: Contribution of early nutrition on the development of malnutrition and allergic diseases in the first year of life: a study protocol for the Mother and Infant Cohort Study (MICOS)

Contribution of early nutrition on the development of malnutrition and allergic diseases in the first year of life: a study protocol for the Mother and Infant Cohort Study (MICOS)

Background: Nutrition and environmental factors are essential for the education of the neonatal immune system. Epidemiological evidence has shown that malnutrition and allergic diseases that occur during early childhood share similar protective and risk factors. This paper describes the protocol of...

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Main Authors:	Woon, Fui Chee, Chin, Yit Siew, Ismail, Intan Hakimah, Chan, Yoke Mun, Batterham, Marijka, Abdul Latiff, Amir Hamzah, Gan, Wan Ying, Appannah, Geeta
Format:	Article
Language:	English
Published:	BioMed Central 2018
Online Access:	http://psasir.upm.edu.my/id/eprint/72119/1/Contribution%20of%20early%20nutrition%20on%20the.pdf http://psasir.upm.edu.my/id/eprint/72119/ https://bmcpediatr.biomedcentral.com/articles/10.1186/s12887-018-1219-3
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spelling	my.upm.eprints.721192020-03-02T06:23:21Z http://psasir.upm.edu.my/id/eprint/72119/ Contribution of early nutrition on the development of malnutrition and allergic diseases in the first year of life: a study protocol for the Mother and Infant Cohort Study (MICOS) Woon, Fui Chee Chin, Yit Siew Ismail, Intan Hakimah Chan, Yoke Mun Batterham, Marijka Abdul Latiff, Amir Hamzah Gan, Wan Ying Appannah, Geeta Background: Nutrition and environmental factors are essential for the education of the neonatal immune system. Epidemiological evidence has shown that malnutrition and allergic diseases that occur during early childhood share similar protective and risk factors. This paper describes the protocol of the Mother and Infant Cohort Study (MICOS), which aims to determine the contribution of early nutrition to the development of malnutrition and allergic diseases in infants’ first year of life. Methods: MICOS is a prospective cohort study conducted at selected government health clinics in two states, namely Selangor and Wilayah Persekutuan Kuala Lumpur, Malaysia. Women in their third trimester of pregnancy are recruited into the study and their infants will be followed-up at 3, 6, and 12 months of age. Information on prenatal factors including socio-demographic characteristics, obstetric history, pre-pregnancy body mass index, gestational weight gain, smoking, family history of allergic diseases, maternal dietary intake and sunlight exposure during pregnancy are obtained through face-to-face interviews. Postnatal factors including dietary intake, sun exposure, and anthropometric measurements of the mothers, as well as feeding practices, dietary intake, anthropometric measurements, and development of allergic diseases of the infants are assessed at each follow-up. Blood samples are collected from the mothers in the third trimester to determine 25-hydroxyvitamin D levels as well as from the infants at age 12 months to determine atopic sensitisation. Discussion: The concept of developmental origins of health and disease (DOHaD) which emphasises on the role of early life environments in shaping future health and disease susceptibility in adulthood has gained a huge interest in recent years. The DOHaD paradigm has influenced many fields of research including malnutrition and allergic diseases. While findings from the developed countries remain controversial, such studies are scarce in developing countries including Malaysia. The present study will determine the cause and effect relationship between early nutrition and the development of malnutrition and allergic diseases in infants’ first year of life. BioMed Central 2018 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/72119/1/Contribution%20of%20early%20nutrition%20on%20the.pdf Woon, Fui Chee and Chin, Yit Siew and Ismail, Intan Hakimah and Chan, Yoke Mun and Batterham, Marijka and Abdul Latiff, Amir Hamzah and Gan, Wan Ying and Appannah, Geeta (2018) Contribution of early nutrition on the development of malnutrition and allergic diseases in the first year of life: a study protocol for the Mother and Infant Cohort Study (MICOS). BMC Pediatrics, 18 (233). pp. 1-9. ISSN 1471-2431 https://bmcpediatr.biomedcentral.com/articles/10.1186/s12887-018-1219-3 10.1186/s12887-018-1219-3
institution	Universiti Putra Malaysia
building	UPM Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Putra Malaysia
content_source	UPM Institutional Repository
url_provider	http://psasir.upm.edu.my/
language	English
description	Background: Nutrition and environmental factors are essential for the education of the neonatal immune system. Epidemiological evidence has shown that malnutrition and allergic diseases that occur during early childhood share similar protective and risk factors. This paper describes the protocol of the Mother and Infant Cohort Study (MICOS), which aims to determine the contribution of early nutrition to the development of malnutrition and allergic diseases in infants’ first year of life. Methods: MICOS is a prospective cohort study conducted at selected government health clinics in two states, namely Selangor and Wilayah Persekutuan Kuala Lumpur, Malaysia. Women in their third trimester of pregnancy are recruited into the study and their infants will be followed-up at 3, 6, and 12 months of age. Information on prenatal factors including socio-demographic characteristics, obstetric history, pre-pregnancy body mass index, gestational weight gain, smoking, family history of allergic diseases, maternal dietary intake and sunlight exposure during pregnancy are obtained through face-to-face interviews. Postnatal factors including dietary intake, sun exposure, and anthropometric measurements of the mothers, as well as feeding practices, dietary intake, anthropometric measurements, and development of allergic diseases of the infants are assessed at each follow-up. Blood samples are collected from the mothers in the third trimester to determine 25-hydroxyvitamin D levels as well as from the infants at age 12 months to determine atopic sensitisation. Discussion: The concept of developmental origins of health and disease (DOHaD) which emphasises on the role of early life environments in shaping future health and disease susceptibility in adulthood has gained a huge interest in recent years. The DOHaD paradigm has influenced many fields of research including malnutrition and allergic diseases. While findings from the developed countries remain controversial, such studies are scarce in developing countries including Malaysia. The present study will determine the cause and effect relationship between early nutrition and the development of malnutrition and allergic diseases in infants’ first year of life.
format	Article
author	Woon, Fui Chee Chin, Yit Siew Ismail, Intan Hakimah Chan, Yoke Mun Batterham, Marijka Abdul Latiff, Amir Hamzah Gan, Wan Ying Appannah, Geeta
spellingShingle	Woon, Fui Chee Chin, Yit Siew Ismail, Intan Hakimah Chan, Yoke Mun Batterham, Marijka Abdul Latiff, Amir Hamzah Gan, Wan Ying Appannah, Geeta Contribution of early nutrition on the development of malnutrition and allergic diseases in the first year of life: a study protocol for the Mother and Infant Cohort Study (MICOS)
author_facet	Woon, Fui Chee Chin, Yit Siew Ismail, Intan Hakimah Chan, Yoke Mun Batterham, Marijka Abdul Latiff, Amir Hamzah Gan, Wan Ying Appannah, Geeta
author_sort	Woon, Fui Chee
title	Contribution of early nutrition on the development of malnutrition and allergic diseases in the first year of life: a study protocol for the Mother and Infant Cohort Study (MICOS)
title_short	Contribution of early nutrition on the development of malnutrition and allergic diseases in the first year of life: a study protocol for the Mother and Infant Cohort Study (MICOS)
title_full	Contribution of early nutrition on the development of malnutrition and allergic diseases in the first year of life: a study protocol for the Mother and Infant Cohort Study (MICOS)
title_fullStr	Contribution of early nutrition on the development of malnutrition and allergic diseases in the first year of life: a study protocol for the Mother and Infant Cohort Study (MICOS)
title_full_unstemmed	Contribution of early nutrition on the development of malnutrition and allergic diseases in the first year of life: a study protocol for the Mother and Infant Cohort Study (MICOS)
title_sort	contribution of early nutrition on the development of malnutrition and allergic diseases in the first year of life: a study protocol for the mother and infant cohort study (micos)
publisher	BioMed Central
publishDate	2018
url	http://psasir.upm.edu.my/id/eprint/72119/1/Contribution%20of%20early%20nutrition%20on%20the.pdf http://psasir.upm.edu.my/id/eprint/72119/ https://bmcpediatr.biomedcentral.com/articles/10.1186/s12887-018-1219-3
_version_	1662756477245325312
score	13.211869

Contribution of early nutrition on the development of malnutrition and allergic diseases in the first year of life: a study protocol for the Mother and Infant Cohort Study (MICOS)

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