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Detection of leptospiral DNA in urine sample following prolonged hospitalization: a case report

We described a case of positive molecular detection of leptospirosis in urine sample following prolonged hospitalization. Relevant clinical history had raised suspicion to leptospirosis infection. A significantly high level of creatinine kinase suggested possibility of rhabdomyolysis. Blood and urin...

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Main Authors: Othman, Shuhaidah, Philip, Noraini, Mohd Taib, Niazlin, Neela, Vasantha Kumari, Chee, Hui Yee
Format: Article
Language:English
Published: Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2019
Online Access:http://psasir.upm.edu.my/id/eprint/70062/1/2019070210045015_MJMHS_SP2_2019.pdf
http://psasir.upm.edu.my/id/eprint/70062/
https://medic.upm.edu.my/upload/dokumen/2019070210045015_MJMHS_SP2_2019.pdf
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spelling my.upm.eprints.700622019-08-16T00:39:29Z http://psasir.upm.edu.my/id/eprint/70062/ Detection of leptospiral DNA in urine sample following prolonged hospitalization: a case report Othman, Shuhaidah Philip, Noraini Mohd Taib, Niazlin Neela, Vasantha Kumari Chee, Hui Yee We described a case of positive molecular detection of leptospirosis in urine sample following prolonged hospitalization. Relevant clinical history had raised suspicion to leptospirosis infection. A significantly high level of creatinine kinase suggested possibility of rhabdomyolysis. Blood and urine samples collected on 4th day of admission were negative for leptospires culture and serological method showed no significant evidences of positive infection. Molecular detection of Leptospira spp. in blood sample was positive but not in urine sample. After seven weeks of infection, leptospiral DNA was detected in urine sample using molecular method. Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2019 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/70062/1/2019070210045015_MJMHS_SP2_2019.pdf Othman, Shuhaidah and Philip, Noraini and Mohd Taib, Niazlin and Neela, Vasantha Kumari and Chee, Hui Yee (2019) Detection of leptospiral DNA in urine sample following prolonged hospitalization: a case report. Malaysian Journal of Medicine and Health Sciences, 15 (SP2). pp. 105-107. ISSN 1675-8544; ESSN: 2636-9346 https://medic.upm.edu.my/upload/dokumen/2019070210045015_MJMHS_SP2_2019.pdf
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description We described a case of positive molecular detection of leptospirosis in urine sample following prolonged hospitalization. Relevant clinical history had raised suspicion to leptospirosis infection. A significantly high level of creatinine kinase suggested possibility of rhabdomyolysis. Blood and urine samples collected on 4th day of admission were negative for leptospires culture and serological method showed no significant evidences of positive infection. Molecular detection of Leptospira spp. in blood sample was positive but not in urine sample. After seven weeks of infection, leptospiral DNA was detected in urine sample using molecular method.
format Article
author Othman, Shuhaidah
Philip, Noraini
Mohd Taib, Niazlin
Neela, Vasantha Kumari
Chee, Hui Yee
spellingShingle Othman, Shuhaidah
Philip, Noraini
Mohd Taib, Niazlin
Neela, Vasantha Kumari
Chee, Hui Yee
Detection of leptospiral DNA in urine sample following prolonged hospitalization: a case report
author_facet Othman, Shuhaidah
Philip, Noraini
Mohd Taib, Niazlin
Neela, Vasantha Kumari
Chee, Hui Yee
author_sort Othman, Shuhaidah
title Detection of leptospiral DNA in urine sample following prolonged hospitalization: a case report
title_short Detection of leptospiral DNA in urine sample following prolonged hospitalization: a case report
title_full Detection of leptospiral DNA in urine sample following prolonged hospitalization: a case report
title_fullStr Detection of leptospiral DNA in urine sample following prolonged hospitalization: a case report
title_full_unstemmed Detection of leptospiral DNA in urine sample following prolonged hospitalization: a case report
title_sort detection of leptospiral dna in urine sample following prolonged hospitalization: a case report
publisher Faculty of Medicine and Health Sciences, Universiti Putra Malaysia
publishDate 2019
url http://psasir.upm.edu.my/id/eprint/70062/1/2019070210045015_MJMHS_SP2_2019.pdf
http://psasir.upm.edu.my/id/eprint/70062/
https://medic.upm.edu.my/upload/dokumen/2019070210045015_MJMHS_SP2_2019.pdf
_version_ 1643839635636355072
score 13.211869

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