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A review on the variable copies of C-C motif chemokine ligand 3 like 1 (CCL3L1) gene among different populations and current methods for quantification

C-C motif Chemokine Ligand 3 Like 1 (CCL3L1) is characterized as a gene with copy number variable (CNV) and clustered at the segmental duplication on chromosome 17q12. CCL3L1 is responsible for the production of macrophage inflammatory protein (MIP) 1α that plays an important function in the immune...

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Main Authors: Jamaluddin, Jalilah, Abu Bakar @ Jamaludin, Suhaili
Format: Article
Language:English
Published: Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2019
Online Access:http://psasir.upm.edu.my/id/eprint/70061/1/2019070210042014_MJMHS_SP2_2019.pdf
http://psasir.upm.edu.my/id/eprint/70061/
https://medic.upm.edu.my/upload/dokumen/2019070210042014_MJMHS_SP2_2019.pdf
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spelling my.upm.eprints.700612019-08-16T00:39:24Z http://psasir.upm.edu.my/id/eprint/70061/ A review on the variable copies of C-C motif chemokine ligand 3 like 1 (CCL3L1) gene among different populations and current methods for quantification Jamaluddin, Jalilah Abu Bakar @ Jamaludin, Suhaili C-C motif Chemokine Ligand 3 Like 1 (CCL3L1) is characterized as a gene with copy number variable (CNV) and clustered at the segmental duplication on chromosome 17q12. CCL3L1 is responsible for the production of macrophage inflammatory protein (MIP) 1α that plays an important function in the immune system and host defense. Various copies range of CCL3L1 have been reported and associated with the diseases in different populations. Thus, this review aimed to summarise the distribution of CCL3L1 copy number from different populations according to the geographical region and highlighted the lacking of data from Malaysian population, which is one of the multi-ethnic countries due to the impacts of CCL3L1 copies on various diseases. Besides, we also outlined the methodologies available for the copy number typing. In overall, this review could provide significant information on the role of CCL3L1 copies in disease association and as well as providing evidence on the population diversity. Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2019 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/70061/1/2019070210042014_MJMHS_SP2_2019.pdf Jamaluddin, Jalilah and Abu Bakar @ Jamaludin, Suhaili (2019) A review on the variable copies of C-C motif chemokine ligand 3 like 1 (CCL3L1) gene among different populations and current methods for quantification. Malaysian Journal of Medicine and Health Sciences, 15 (SP2). pp. 96-104. ISSN 1675-8544; ESSN: 2636-9346 https://medic.upm.edu.my/upload/dokumen/2019070210042014_MJMHS_SP2_2019.pdf
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description C-C motif Chemokine Ligand 3 Like 1 (CCL3L1) is characterized as a gene with copy number variable (CNV) and clustered at the segmental duplication on chromosome 17q12. CCL3L1 is responsible for the production of macrophage inflammatory protein (MIP) 1α that plays an important function in the immune system and host defense. Various copies range of CCL3L1 have been reported and associated with the diseases in different populations. Thus, this review aimed to summarise the distribution of CCL3L1 copy number from different populations according to the geographical region and highlighted the lacking of data from Malaysian population, which is one of the multi-ethnic countries due to the impacts of CCL3L1 copies on various diseases. Besides, we also outlined the methodologies available for the copy number typing. In overall, this review could provide significant information on the role of CCL3L1 copies in disease association and as well as providing evidence on the population diversity.
format Article
author Jamaluddin, Jalilah
Abu Bakar @ Jamaludin, Suhaili
spellingShingle Jamaluddin, Jalilah
Abu Bakar @ Jamaludin, Suhaili
A review on the variable copies of C-C motif chemokine ligand 3 like 1 (CCL3L1) gene among different populations and current methods for quantification
author_facet Jamaluddin, Jalilah
Abu Bakar @ Jamaludin, Suhaili
author_sort Jamaluddin, Jalilah
title A review on the variable copies of C-C motif chemokine ligand 3 like 1 (CCL3L1) gene among different populations and current methods for quantification
title_short A review on the variable copies of C-C motif chemokine ligand 3 like 1 (CCL3L1) gene among different populations and current methods for quantification
title_full A review on the variable copies of C-C motif chemokine ligand 3 like 1 (CCL3L1) gene among different populations and current methods for quantification
title_fullStr A review on the variable copies of C-C motif chemokine ligand 3 like 1 (CCL3L1) gene among different populations and current methods for quantification
title_full_unstemmed A review on the variable copies of C-C motif chemokine ligand 3 like 1 (CCL3L1) gene among different populations and current methods for quantification
title_sort review on the variable copies of c-c motif chemokine ligand 3 like 1 (ccl3l1) gene among different populations and current methods for quantification
publisher Faculty of Medicine and Health Sciences, Universiti Putra Malaysia
publishDate 2019
url http://psasir.upm.edu.my/id/eprint/70061/1/2019070210042014_MJMHS_SP2_2019.pdf
http://psasir.upm.edu.my/id/eprint/70061/
https://medic.upm.edu.my/upload/dokumen/2019070210042014_MJMHS_SP2_2019.pdf
_version_ 1643839635339608064
score 13.211869

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