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Investigation of the effect of pH environment on the properties of magnetite nanoparticles used in nano drug delivery production prepared by co-precipitation method

In the present work, magnetic nanoparticles coated with polyethylene glycol and anticancer liver drug in different pH 4 and 8 were synthesized by co-precipitation method. In order to synthesize magnetic nanoparticles, from polyethylene glycol as a stabilizing agent and 5-fluorouracil for anticancer...

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Main Authors: Ebadi, Mona, Saifullah, Bullo, Hussein, Mohd Zobir
Format: Conference or Workshop Item
Language:English
Published: 2018
Online Access:http://psasir.upm.edu.my/id/eprint/65462/1/45.pdf
http://psasir.upm.edu.my/id/eprint/65462/
http://www.samn2018.upm.edu.my/doc/45.pdf
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spelling my.upm.eprints.654622018-10-08T02:41:08Z http://psasir.upm.edu.my/id/eprint/65462/ Investigation of the effect of pH environment on the properties of magnetite nanoparticles used in nano drug delivery production prepared by co-precipitation method Ebadi, Mona Saifullah, Bullo Hussein, Mohd Zobir In the present work, magnetic nanoparticles coated with polyethylene glycol and anticancer liver drug in different pH 4 and 8 were synthesized by co-precipitation method. In order to synthesize magnetic nanoparticles, from polyethylene glycol as a stabilizing agent and 5-fluorouracil for anticancer liver agent were used. We have tried to investigate the effect of PH in two acidic and alkaline environments (PH 4 and PH 8) on the properties of coated nanoparticles in drug delivery. Magnetite nanoparticles were first synthesized. In the following, magnetite nanoparticles have been synthesized in anti-cancer drug was intercalated into the interlayer of the layered double hydroxide (LDH). Eventually, changed PH in two acidic and alkaline environments. Structural and magnetic properties of magnetic nanoparticles were investigated by XRD and VSM. The X-ray diffraction results showed that, the sample is composed of iron oxides which construct the core. VSM analysis of synthesized samples in pH 4 and pH 8 showed superparamagnetic property with magnetic saturation values of 27 and 40 emu/g, respectively. 2018 Conference or Workshop Item PeerReviewed text en http://psasir.upm.edu.my/id/eprint/65462/1/45.pdf Ebadi, Mona and Saifullah, Bullo and Hussein, Mohd Zobir (2018) Investigation of the effect of pH environment on the properties of magnetite nanoparticles used in nano drug delivery production prepared by co-precipitation method. In: 2nd International Symposium on Advanced Materials and Nanotechnology (i-SAMN 2018), 15-16 Aug. 2018, The Everly Putrajaya, Malaysia. (pp. 82-83). http://www.samn2018.upm.edu.my/doc/45.pdf
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description In the present work, magnetic nanoparticles coated with polyethylene glycol and anticancer liver drug in different pH 4 and 8 were synthesized by co-precipitation method. In order to synthesize magnetic nanoparticles, from polyethylene glycol as a stabilizing agent and 5-fluorouracil for anticancer liver agent were used. We have tried to investigate the effect of PH in two acidic and alkaline environments (PH 4 and PH 8) on the properties of coated nanoparticles in drug delivery. Magnetite nanoparticles were first synthesized. In the following, magnetite nanoparticles have been synthesized in anti-cancer drug was intercalated into the interlayer of the layered double hydroxide (LDH). Eventually, changed PH in two acidic and alkaline environments. Structural and magnetic properties of magnetic nanoparticles were investigated by XRD and VSM. The X-ray diffraction results showed that, the sample is composed of iron oxides which construct the core. VSM analysis of synthesized samples in pH 4 and pH 8 showed superparamagnetic property with magnetic saturation values of 27 and 40 emu/g, respectively.
format Conference or Workshop Item
author Ebadi, Mona
Saifullah, Bullo
Hussein, Mohd Zobir
spellingShingle Ebadi, Mona
Saifullah, Bullo
Hussein, Mohd Zobir
Investigation of the effect of pH environment on the properties of magnetite nanoparticles used in nano drug delivery production prepared by co-precipitation method
author_facet Ebadi, Mona
Saifullah, Bullo
Hussein, Mohd Zobir
author_sort Ebadi, Mona
title Investigation of the effect of pH environment on the properties of magnetite nanoparticles used in nano drug delivery production prepared by co-precipitation method
title_short Investigation of the effect of pH environment on the properties of magnetite nanoparticles used in nano drug delivery production prepared by co-precipitation method
title_full Investigation of the effect of pH environment on the properties of magnetite nanoparticles used in nano drug delivery production prepared by co-precipitation method
title_fullStr Investigation of the effect of pH environment on the properties of magnetite nanoparticles used in nano drug delivery production prepared by co-precipitation method
title_full_unstemmed Investigation of the effect of pH environment on the properties of magnetite nanoparticles used in nano drug delivery production prepared by co-precipitation method
title_sort investigation of the effect of ph environment on the properties of magnetite nanoparticles used in nano drug delivery production prepared by co-precipitation method
publishDate 2018
url http://psasir.upm.edu.my/id/eprint/65462/1/45.pdf
http://psasir.upm.edu.my/id/eprint/65462/
http://www.samn2018.upm.edu.my/doc/45.pdf
_version_ 1643838321787404288
score 13.211869

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