Cover Image

Screening of ionic liquids for PUFA extraction from microalgal biomass using COSMO-RS

Omega-3 Poly Unsaturated Fatty Acids (PUFA) particularly eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA) have many health benefits including reducing the risk of cancer, cardiovascular disease, autoimmune, inflammatory disorders, cystic fibrosis, disrupted neurological function, bowel di...

Full description

Saved in:
Bibliographic Details
Main Authors: Motlagh, Shiva Rezaei, Harun, Mohd Razif
Format: Conference or Workshop Item
Language:English
Published: 2017
Online Access:http://psasir.upm.edu.my/id/eprint/64369/1/ENG%20%26%20New%20Tech%20Oral%20111117%205.pdf
http://psasir.upm.edu.my/id/eprint/64369/
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.upm.eprints.64369
record_format eprints
spelling my.upm.eprints.643692018-07-04T02:38:02Z http://psasir.upm.edu.my/id/eprint/64369/ Screening of ionic liquids for PUFA extraction from microalgal biomass using COSMO-RS Motlagh, Shiva Rezaei Harun, Mohd Razif Omega-3 Poly Unsaturated Fatty Acids (PUFA) particularly eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA) have many health benefits including reducing the risk of cancer, cardiovascular disease, autoimmune, inflammatory disorders, cystic fibrosis, disrupted neurological function, bowel disease and mental illness. The EPA and DHA from microalgae are favorable due to algal is farmed in a controlled environment that avoids harmful contamination such as methyl mercury, copper from the sea. Moreover, microalgae oil do not have the problem to deficiency of vitamin E unlike fish oil. It has also the advantage of presenting neither an unpleasant odour nor a high amount of cholesterol, and contains squalene and phytosterols, which offer additional benefits to human health. However, the existing conventional methods of lipid extraction like soxhlet consume large amount of solvent and consider as high toxic and energy intensive methods. Ionic liquids (ILs) is one of the new classes of solvent that has potential in extracting the microalgae PUFA. It provides low vapor pressure, high thermal stability, non-toxicity and dissolve polar, non polar organic, inorganic and polymeric components. However, very limited research has been conducted on extracting microalgae PUFA using ILs. Therefore, this study aims to screen the potential ILs that can be used in the microalgae extraction process. The screening work was carried out using Continuum Solvation Models for Real Solvents (COSMO-RS). In this research use cosmo-rs to investigate the effect of hydrophilic and hydrophobic anions base ILs and also effect of the increase alkyl chain length from C2 to C8 on the EPA and DHA extraction. Cosmo-rs done this simulation by the calculation of activity coefficient (γ). It was found that the lowest activity coefficient has the best interaction between the solute and solvent. According to the results lowest activity coefficient for EPA and DHA extraction belong to [Cl] as anion for the imidazolium, pyridinium and pyrrolidinium with different alkyl chains. The effectiveness of those combinations will be further tested in the microalgae extraction. 2017 Conference or Workshop Item PeerReviewed text en http://psasir.upm.edu.my/id/eprint/64369/1/ENG%20%26%20New%20Tech%20Oral%20111117%205.pdf Motlagh, Shiva Rezaei and Harun, Mohd Razif (2017) Screening of ionic liquids for PUFA extraction from microalgal biomass using COSMO-RS. In: 5th International Symposium on Applied Engineering and Sciences (SAES2017), 14-15 Nov. 2017, Universiti Putra Malaysia. (p. 5).
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description Omega-3 Poly Unsaturated Fatty Acids (PUFA) particularly eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA) have many health benefits including reducing the risk of cancer, cardiovascular disease, autoimmune, inflammatory disorders, cystic fibrosis, disrupted neurological function, bowel disease and mental illness. The EPA and DHA from microalgae are favorable due to algal is farmed in a controlled environment that avoids harmful contamination such as methyl mercury, copper from the sea. Moreover, microalgae oil do not have the problem to deficiency of vitamin E unlike fish oil. It has also the advantage of presenting neither an unpleasant odour nor a high amount of cholesterol, and contains squalene and phytosterols, which offer additional benefits to human health. However, the existing conventional methods of lipid extraction like soxhlet consume large amount of solvent and consider as high toxic and energy intensive methods. Ionic liquids (ILs) is one of the new classes of solvent that has potential in extracting the microalgae PUFA. It provides low vapor pressure, high thermal stability, non-toxicity and dissolve polar, non polar organic, inorganic and polymeric components. However, very limited research has been conducted on extracting microalgae PUFA using ILs. Therefore, this study aims to screen the potential ILs that can be used in the microalgae extraction process. The screening work was carried out using Continuum Solvation Models for Real Solvents (COSMO-RS). In this research use cosmo-rs to investigate the effect of hydrophilic and hydrophobic anions base ILs and also effect of the increase alkyl chain length from C2 to C8 on the EPA and DHA extraction. Cosmo-rs done this simulation by the calculation of activity coefficient (γ). It was found that the lowest activity coefficient has the best interaction between the solute and solvent. According to the results lowest activity coefficient for EPA and DHA extraction belong to [Cl] as anion for the imidazolium, pyridinium and pyrrolidinium with different alkyl chains. The effectiveness of those combinations will be further tested in the microalgae extraction.
format Conference or Workshop Item
author Motlagh, Shiva Rezaei
Harun, Mohd Razif
spellingShingle Motlagh, Shiva Rezaei
Harun, Mohd Razif
Screening of ionic liquids for PUFA extraction from microalgal biomass using COSMO-RS
author_facet Motlagh, Shiva Rezaei
Harun, Mohd Razif
author_sort Motlagh, Shiva Rezaei
title Screening of ionic liquids for PUFA extraction from microalgal biomass using COSMO-RS
title_short Screening of ionic liquids for PUFA extraction from microalgal biomass using COSMO-RS
title_full Screening of ionic liquids for PUFA extraction from microalgal biomass using COSMO-RS
title_fullStr Screening of ionic liquids for PUFA extraction from microalgal biomass using COSMO-RS
title_full_unstemmed Screening of ionic liquids for PUFA extraction from microalgal biomass using COSMO-RS
title_sort screening of ionic liquids for pufa extraction from microalgal biomass using cosmo-rs
publishDate 2017
url http://psasir.upm.edu.my/id/eprint/64369/1/ENG%20%26%20New%20Tech%20Oral%20111117%205.pdf
http://psasir.upm.edu.my/id/eprint/64369/
_version_ 1643838002795905024
score 13.211869

Similar Items