Development of a PrGO-Modified electrode for uric acid determination in the presence of ascorbic acid by an electrochemical technique

An attractive electrochemical sensor of poly(3,4-ethylenedioxythiophene)/reduced graphene oxide electrode (PrGO) was developed for an electrochemical technique for uric acid (UA) detection in the presence of ascorbic acid (AA). PrGO composite film showed an improved electrocatalytic activity towards...

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Main Authors: Tukimin, Nurulkhalilah, Abdullah, Jaafar, Sulaiman, Yusran
Format: Article
Language:English
Published: Multidisciplinary Digital Publishing Institute 2017
Online Access:http://psasir.upm.edu.my/id/eprint/61448/1/Development%20of%20a%20PrGO.pdf
http://psasir.upm.edu.my/id/eprint/61448/
http://www.mdpi.com/1424-8220/17/7/1539
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spelling my.upm.eprints.614482018-10-09T07:52:00Z http://psasir.upm.edu.my/id/eprint/61448/ Development of a PrGO-Modified electrode for uric acid determination in the presence of ascorbic acid by an electrochemical technique Tukimin, Nurulkhalilah Abdullah, Jaafar Sulaiman, Yusran An attractive electrochemical sensor of poly(3,4-ethylenedioxythiophene)/reduced graphene oxide electrode (PrGO) was developed for an electrochemical technique for uric acid (UA) detection in the presence of ascorbic acid (AA). PrGO composite film showed an improved electrocatalytic activity towards UA oxidation in pH 6.0 (0.1 M PBS). The PrGO composite exhibited a high current signal and low charge transfer resistance (Rct) compared to a reduced graphene oxide (rGO) electrode or a bare glassy carbon electrode (GCE). The limit of detection and sensitivity of PrGO for the detection of UA are 0.19 μM (S/N = 3) and 0.01 μA/μM, respectively, in the range of 1–300 μM of UA. Multidisciplinary Digital Publishing Institute 2017-07 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/61448/1/Development%20of%20a%20PrGO.pdf Tukimin, Nurulkhalilah and Abdullah, Jaafar and Sulaiman, Yusran (2017) Development of a PrGO-Modified electrode for uric acid determination in the presence of ascorbic acid by an electrochemical technique. Sensors, 17 (7). pp. 1-12. ISSN 1424-8220 http://www.mdpi.com/1424-8220/17/7/1539 10.3390/s17071539
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description An attractive electrochemical sensor of poly(3,4-ethylenedioxythiophene)/reduced graphene oxide electrode (PrGO) was developed for an electrochemical technique for uric acid (UA) detection in the presence of ascorbic acid (AA). PrGO composite film showed an improved electrocatalytic activity towards UA oxidation in pH 6.0 (0.1 M PBS). The PrGO composite exhibited a high current signal and low charge transfer resistance (Rct) compared to a reduced graphene oxide (rGO) electrode or a bare glassy carbon electrode (GCE). The limit of detection and sensitivity of PrGO for the detection of UA are 0.19 μM (S/N = 3) and 0.01 μA/μM, respectively, in the range of 1–300 μM of UA.
format Article
author Tukimin, Nurulkhalilah
Abdullah, Jaafar
Sulaiman, Yusran
spellingShingle Tukimin, Nurulkhalilah
Abdullah, Jaafar
Sulaiman, Yusran
Development of a PrGO-Modified electrode for uric acid determination in the presence of ascorbic acid by an electrochemical technique
author_facet Tukimin, Nurulkhalilah
Abdullah, Jaafar
Sulaiman, Yusran
author_sort Tukimin, Nurulkhalilah
title Development of a PrGO-Modified electrode for uric acid determination in the presence of ascorbic acid by an electrochemical technique
title_short Development of a PrGO-Modified electrode for uric acid determination in the presence of ascorbic acid by an electrochemical technique
title_full Development of a PrGO-Modified electrode for uric acid determination in the presence of ascorbic acid by an electrochemical technique
title_fullStr Development of a PrGO-Modified electrode for uric acid determination in the presence of ascorbic acid by an electrochemical technique
title_full_unstemmed Development of a PrGO-Modified electrode for uric acid determination in the presence of ascorbic acid by an electrochemical technique
title_sort development of a prgo-modified electrode for uric acid determination in the presence of ascorbic acid by an electrochemical technique
publisher Multidisciplinary Digital Publishing Institute
publishDate 2017
url http://psasir.upm.edu.my/id/eprint/61448/1/Development%20of%20a%20PrGO.pdf
http://psasir.upm.edu.my/id/eprint/61448/
http://www.mdpi.com/1424-8220/17/7/1539
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score 13.211869