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Haruan (Channastriatus) extract as halal innovation productsfor healing of gastric ulcer: preliminary investigation

Channastriatus (Haruan), a freshwater and snakehead fish, is traditionally used by the Malay to heal wound and lessens post-operative pain and discomfort. The objective of the present study is to elucidate the gastroprotective activity of chloroform:metanol extract of C. striatus fillet. The fillets...

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Main Authors: Azemi, Ahmad Khusairi, Md Tohid, Siti Farah, Somchit, Muhammad Nazrul, Mat Jais, Abdul Manan, Zakaria, Zainul Amiruddin
Format: Conference or Workshop Item
Language:English
Published: Halal Products Research Institute, Universiti Putra Malaysia 2014
Online Access:http://psasir.upm.edu.my/id/eprint/60574/1/M19.pdf
http://psasir.upm.edu.my/id/eprint/60574/
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spelling my.upm.eprints.605742018-06-07T08:42:11Z http://psasir.upm.edu.my/id/eprint/60574/ Haruan (Channastriatus) extract as halal innovation productsfor healing of gastric ulcer: preliminary investigation Azemi, Ahmad Khusairi Md Tohid, Siti Farah Somchit, Muhammad Nazrul Mat Jais, Abdul Manan Zakaria, Zainul Amiruddin Channastriatus (Haruan), a freshwater and snakehead fish, is traditionally used by the Malay to heal wound and lessens post-operative pain and discomfort. The objective of the present study is to elucidate the gastroprotective activity of chloroform:metanol extract of C. striatus fillet. The fillets were extracted using the methanol: chloroform (2:1; v/v) solvent system. The extract (labeled as MCECS), prepared in the doses of 50, 250, and 500 mg/kg, was orally administered into rats for 7 continuous days and then the animals were subjected to the ethanol- and indomethacin-induced gastric ulcer models. Following the euthanization of treated rats, the stomach was callected for macroscopic and microscopic analysis. The results showed that oral administration of MCECS exhibited significant (p<0.05) and dose-dependent antiulcer activity when assessed using both models of gastric ulcer. In addition, the macroscopic findings were supported by the microscopic observations. In conclusion, C. striatus extract exerted remarkable antiulcer activity that warranted in-depth studies in an attempt to develop its extract as a halal-based product. Halal Products Research Institute, Universiti Putra Malaysia 2014 Conference or Workshop Item PeerReviewed text en http://psasir.upm.edu.my/id/eprint/60574/1/M19.pdf Azemi, Ahmad Khusairi and Md Tohid, Siti Farah and Somchit, Muhammad Nazrul and Mat Jais, Abdul Manan and Zakaria, Zainul Amiruddin (2014) Haruan (Channastriatus) extract as halal innovation productsfor healing of gastric ulcer: preliminary investigation. In: Malaysia International Halal Research & Education Conference 2014 (MIHREC 2014), 2-4 Dec. 2014, Marriott Putrajaya Hotel, Malaysia. (pp. 217-222).
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description Channastriatus (Haruan), a freshwater and snakehead fish, is traditionally used by the Malay to heal wound and lessens post-operative pain and discomfort. The objective of the present study is to elucidate the gastroprotective activity of chloroform:metanol extract of C. striatus fillet. The fillets were extracted using the methanol: chloroform (2:1; v/v) solvent system. The extract (labeled as MCECS), prepared in the doses of 50, 250, and 500 mg/kg, was orally administered into rats for 7 continuous days and then the animals were subjected to the ethanol- and indomethacin-induced gastric ulcer models. Following the euthanization of treated rats, the stomach was callected for macroscopic and microscopic analysis. The results showed that oral administration of MCECS exhibited significant (p<0.05) and dose-dependent antiulcer activity when assessed using both models of gastric ulcer. In addition, the macroscopic findings were supported by the microscopic observations. In conclusion, C. striatus extract exerted remarkable antiulcer activity that warranted in-depth studies in an attempt to develop its extract as a halal-based product.
format Conference or Workshop Item
author Azemi, Ahmad Khusairi
Md Tohid, Siti Farah
Somchit, Muhammad Nazrul
Mat Jais, Abdul Manan
Zakaria, Zainul Amiruddin
spellingShingle Azemi, Ahmad Khusairi
Md Tohid, Siti Farah
Somchit, Muhammad Nazrul
Mat Jais, Abdul Manan
Zakaria, Zainul Amiruddin
Haruan (Channastriatus) extract as halal innovation productsfor healing of gastric ulcer: preliminary investigation
author_facet Azemi, Ahmad Khusairi
Md Tohid, Siti Farah
Somchit, Muhammad Nazrul
Mat Jais, Abdul Manan
Zakaria, Zainul Amiruddin
author_sort Azemi, Ahmad Khusairi
title Haruan (Channastriatus) extract as halal innovation productsfor healing of gastric ulcer: preliminary investigation
title_short Haruan (Channastriatus) extract as halal innovation productsfor healing of gastric ulcer: preliminary investigation
title_full Haruan (Channastriatus) extract as halal innovation productsfor healing of gastric ulcer: preliminary investigation
title_fullStr Haruan (Channastriatus) extract as halal innovation productsfor healing of gastric ulcer: preliminary investigation
title_full_unstemmed Haruan (Channastriatus) extract as halal innovation productsfor healing of gastric ulcer: preliminary investigation
title_sort haruan (channastriatus) extract as halal innovation productsfor healing of gastric ulcer: preliminary investigation
publisher Halal Products Research Institute, Universiti Putra Malaysia
publishDate 2014
url http://psasir.upm.edu.my/id/eprint/60574/1/M19.pdf
http://psasir.upm.edu.my/id/eprint/60574/
_version_ 1643837398758457344
score 13.211869

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