Halophenol Rearrangement in Lewis Acid-Catalyzed Friedel–Crafts Conditions: Evidence of Competitive Initial Protonation and Acylation

Halogen rearrangement was observed during the Lewis acid-catalyzed Friedel–Crafts reaction of phthalic anhydride with bromophenols or bromoanisole. Further investigation revealed that 2-, 3-, and 4-bromophenols undergo rearrangement into other isomers under these reaction conditions. Product distrib...

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Bibliographic Details
Main Authors: Koushik, Saha, Lajis, Md Nordin, Abas, Faridah, Ali Naji, Nabil, Hamzah, A. Sazali, Shaari, Khozirah
Format: Article
Language:English
English
Published: CSIRO Publishing 2008
Online Access:http://psasir.upm.edu.my/id/eprint/6021/1/Halophenol%20Rearrangement%20in%20Lewis%20Acid.pdf
http://psasir.upm.edu.my/id/eprint/6021/
http://dx.doi.org/10.1071/CH08084
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