Cover Image

Nanocrystalline cellulose, an environmental friendly nanoparticle for pharmaceutical application – a quick study

Nanocrystalline cellulose (NCC) is probably the most abundant nano material can be found in nature. It offers not only substantial environmental advantage due to its intrinsic biocompatibility and biodegradability, but also outstanding aspect ratio, tension modulus, bioavailability and permeability....

Full description

Saved in:
Bibliographic Details
Main Authors: Song, Yee Kai, Chew, Irene Mei Leng, Choong, Thomas Shean Yaw, Tan, Khang Wei
Format: Conference or Workshop Item
Language:English
Published: EDP Sciences 2016
Online Access:http://psasir.upm.edu.my/id/eprint/57649/1/57649.pdf
http://psasir.upm.edu.my/id/eprint/57649/
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.upm.eprints.57649
record_format eprints
spelling my.upm.eprints.576492017-10-24T09:08:43Z http://psasir.upm.edu.my/id/eprint/57649/ Nanocrystalline cellulose, an environmental friendly nanoparticle for pharmaceutical application – a quick study Song, Yee Kai Chew, Irene Mei Leng Choong, Thomas Shean Yaw Tan, Khang Wei Nanocrystalline cellulose (NCC) is probably the most abundant nano material can be found in nature. It offers not only substantial environmental advantage due to its intrinsic biocompatibility and biodegradability, but also outstanding aspect ratio, tension modulus, bioavailability and permeability. NCC can be isolated from low value biomass through a well-developed acid hydrolysis method, and the structure can be readily manipulated during extraction to obtain desirable size distribution, surface charge and degree of crystallinity. Erratic absorption of drug has been a major issue for years until the emergence of nanoparticle adopted as smart vehicle for drug delivery. However, due to inevitably severe toxicity and the side effect from ordinary nanoparticle, the exploration of green nanoparticles are catching escalating attention is now in urge. Microcrystalline cellulose (MCC) has long been an option, nevertheless, due to their relatively low surface charge compared to total volume, drug release in a control manner was hardly satisfied. It is suggested that the above limitation can be overcome by nanocrystalline cellulose. This article discusses and explores their potential in cosmetic, personal care and pharmaceutical application, and the recent development in term of preparation and characteristic. EDP Sciences 2016 Conference or Workshop Item PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/57649/1/57649.pdf Song, Yee Kai and Chew, Irene Mei Leng and Choong, Thomas Shean Yaw and Tan, Khang Wei (2016) Nanocrystalline cellulose, an environmental friendly nanoparticle for pharmaceutical application – a quick study. In: 2016 3rd International Conference on Chemical and Biological Sciences (ICCBS 2016), 23-25 Mar. 2016, Amsterdam, Netherlands. (pp. 1-5). 10.1051/matecconf/20166001006
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description Nanocrystalline cellulose (NCC) is probably the most abundant nano material can be found in nature. It offers not only substantial environmental advantage due to its intrinsic biocompatibility and biodegradability, but also outstanding aspect ratio, tension modulus, bioavailability and permeability. NCC can be isolated from low value biomass through a well-developed acid hydrolysis method, and the structure can be readily manipulated during extraction to obtain desirable size distribution, surface charge and degree of crystallinity. Erratic absorption of drug has been a major issue for years until the emergence of nanoparticle adopted as smart vehicle for drug delivery. However, due to inevitably severe toxicity and the side effect from ordinary nanoparticle, the exploration of green nanoparticles are catching escalating attention is now in urge. Microcrystalline cellulose (MCC) has long been an option, nevertheless, due to their relatively low surface charge compared to total volume, drug release in a control manner was hardly satisfied. It is suggested that the above limitation can be overcome by nanocrystalline cellulose. This article discusses and explores their potential in cosmetic, personal care and pharmaceutical application, and the recent development in term of preparation and characteristic.
format Conference or Workshop Item
author Song, Yee Kai
Chew, Irene Mei Leng
Choong, Thomas Shean Yaw
Tan, Khang Wei
spellingShingle Song, Yee Kai
Chew, Irene Mei Leng
Choong, Thomas Shean Yaw
Tan, Khang Wei
Nanocrystalline cellulose, an environmental friendly nanoparticle for pharmaceutical application – a quick study
author_facet Song, Yee Kai
Chew, Irene Mei Leng
Choong, Thomas Shean Yaw
Tan, Khang Wei
author_sort Song, Yee Kai
title Nanocrystalline cellulose, an environmental friendly nanoparticle for pharmaceutical application – a quick study
title_short Nanocrystalline cellulose, an environmental friendly nanoparticle for pharmaceutical application – a quick study
title_full Nanocrystalline cellulose, an environmental friendly nanoparticle for pharmaceutical application – a quick study
title_fullStr Nanocrystalline cellulose, an environmental friendly nanoparticle for pharmaceutical application – a quick study
title_full_unstemmed Nanocrystalline cellulose, an environmental friendly nanoparticle for pharmaceutical application – a quick study
title_sort nanocrystalline cellulose, an environmental friendly nanoparticle for pharmaceutical application – a quick study
publisher EDP Sciences
publishDate 2016
url http://psasir.upm.edu.my/id/eprint/57649/1/57649.pdf
http://psasir.upm.edu.my/id/eprint/57649/
_version_ 1643836550171066368
score 13.211869

Similar Items