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Morphological features analysis in pathogenic dengue infection as an alternative screening method

Dengue is one of the most widespread mosquito-borne infections in Malaysia. The diagnosis still remains a challenge in area of disease confirmation where it could not be easily differentiated with other febrile illnesses even though the diagnosis of classical dengue fever and dengue haemorrhagic fev...

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Main Authors: Mohd Yunus, Yusmi, Narowi, Mardhiyyati, Ahmad Mulyadi Lai, Henkie Isahwan
Format: Article
Language:English
Published: Human Resource Management Academic Research Society 2017
Online Access:http://psasir.upm.edu.my/id/eprint/56628/1/Morphological%20features%20analysis%20in%20pathogenic%20dengue%20infection%20as%20an%20alternative%20screening%20method.pdf
http://psasir.upm.edu.my/id/eprint/56628/
http://hrmars.com/index.php/journals/archive_detail/IJARBSS/170
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spelling my.upm.eprints.566282017-08-03T05:18:52Z http://psasir.upm.edu.my/id/eprint/56628/ Morphological features analysis in pathogenic dengue infection as an alternative screening method Mohd Yunus, Yusmi Narowi, Mardhiyyati Ahmad Mulyadi Lai, Henkie Isahwan Dengue is one of the most widespread mosquito-borne infections in Malaysia. The diagnosis still remains a challenge in area of disease confirmation where it could not be easily differentiated with other febrile illnesses even though the diagnosis of classical dengue fever and dengue haemorrhagic fever can be recognized clinically. The clinical diagnosis also can be difficult where the signs and symptoms presented are easily confused with malaria, leptospirosis and typhoid fever. Therefore, an early and effective evaluation of the peripheral blood can be very helpful in patient management. The objectives of this study are to determine the morphological features in peripheral blood film (PBF) of pathogenic dengue infection. 30 PBF of positive dengue infection in University Malaya Medical centre (UMMC) had been examined in this study where atypical lymphocytes [n=27, (90%)] and thrombocytopenia [n=22, (73.3%)] were consistently found. Presence of thrombocytopenia and presence of atypical lymphocytes in PBF are important diagnostic clues for early diagnosis of dengue infection which could be potentially useful parameter in screening dengue. Therefore, PBF can have a significant function in supporting the diagnosis of dengue which can act as complement to the full blood count and serological diagnosis of dengue especially in cases where the clinical manifestation are abnormal. Human Resource Management Academic Research Society 2017 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/56628/1/Morphological%20features%20analysis%20in%20pathogenic%20dengue%20infection%20as%20an%20alternative%20screening%20method.pdf Mohd Yunus, Yusmi and Narowi, Mardhiyyati and Ahmad Mulyadi Lai, Henkie Isahwan (2017) Morphological features analysis in pathogenic dengue infection as an alternative screening method. International Journal of Academic Research in Business and Social Sciences, 7 (2). pp. 801-811. ISSN 2222-6990 http://hrmars.com/index.php/journals/archive_detail/IJARBSS/170 10.6007/IJARBSS/v7-i2/2716
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description Dengue is one of the most widespread mosquito-borne infections in Malaysia. The diagnosis still remains a challenge in area of disease confirmation where it could not be easily differentiated with other febrile illnesses even though the diagnosis of classical dengue fever and dengue haemorrhagic fever can be recognized clinically. The clinical diagnosis also can be difficult where the signs and symptoms presented are easily confused with malaria, leptospirosis and typhoid fever. Therefore, an early and effective evaluation of the peripheral blood can be very helpful in patient management. The objectives of this study are to determine the morphological features in peripheral blood film (PBF) of pathogenic dengue infection. 30 PBF of positive dengue infection in University Malaya Medical centre (UMMC) had been examined in this study where atypical lymphocytes [n=27, (90%)] and thrombocytopenia [n=22, (73.3%)] were consistently found. Presence of thrombocytopenia and presence of atypical lymphocytes in PBF are important diagnostic clues for early diagnosis of dengue infection which could be potentially useful parameter in screening dengue. Therefore, PBF can have a significant function in supporting the diagnosis of dengue which can act as complement to the full blood count and serological diagnosis of dengue especially in cases where the clinical manifestation are abnormal.
format Article
author Mohd Yunus, Yusmi
Narowi, Mardhiyyati
Ahmad Mulyadi Lai, Henkie Isahwan
spellingShingle Mohd Yunus, Yusmi
Narowi, Mardhiyyati
Ahmad Mulyadi Lai, Henkie Isahwan
Morphological features analysis in pathogenic dengue infection as an alternative screening method
author_facet Mohd Yunus, Yusmi
Narowi, Mardhiyyati
Ahmad Mulyadi Lai, Henkie Isahwan
author_sort Mohd Yunus, Yusmi
title Morphological features analysis in pathogenic dengue infection as an alternative screening method
title_short Morphological features analysis in pathogenic dengue infection as an alternative screening method
title_full Morphological features analysis in pathogenic dengue infection as an alternative screening method
title_fullStr Morphological features analysis in pathogenic dengue infection as an alternative screening method
title_full_unstemmed Morphological features analysis in pathogenic dengue infection as an alternative screening method
title_sort morphological features analysis in pathogenic dengue infection as an alternative screening method
publisher Human Resource Management Academic Research Society
publishDate 2017
url http://psasir.upm.edu.my/id/eprint/56628/1/Morphological%20features%20analysis%20in%20pathogenic%20dengue%20infection%20as%20an%20alternative%20screening%20method.pdf
http://psasir.upm.edu.my/id/eprint/56628/
http://hrmars.com/index.php/journals/archive_detail/IJARBSS/170
_version_ 1643836247255285760
score 13.211869

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