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Experimental and numerical study of stenotic flows

Atherosclerosis has been leading cause of deaths in several countries. Recent technical advances have allowed the investigation of stenotic flows and in understanding the implications with increased severity. Such studies shall provide detailed understanding of flow across stenosis and its progressi...

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Main Authors:	Abdul Khader, Shah Mohammed, Adathala, Rajeev, Ayachit, Anurag, Pai, Raghuvir, Vayalappil, Muraleedharan C., Zuber, Mohammad, Rao, V. R. K.
Format:	Article
Language:	English
Published:	American Scientific Publishers 2016
Online Access:	http://psasir.upm.edu.my/id/eprint/54231/1/Experimental%20and%20numerical%20study%20of%20stenotic%20flows%20.pdf http://psasir.upm.edu.my/id/eprint/54231/ http://www.ingentaconnect.com/content/asp/jmihi/2016/00000006/00000006/art00025
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spelling	my.upm.eprints.542312018-03-08T02:35:50Z http://psasir.upm.edu.my/id/eprint/54231/ Experimental and numerical study of stenotic flows Abdul Khader, Shah Mohammed Adathala, Rajeev Ayachit, Anurag Pai, Raghuvir Vayalappil, Muraleedharan C. Zuber, Mohammad Rao, V. R. K. Atherosclerosis has been leading cause of deaths in several countries. Recent technical advances have allowed the investigation of stenotic flows and in understanding the implications with increased severity. Such studies shall provide detailed understanding of flow across stenosis and its progression. In the present study, a large artery representing segment of aorta is considered as test specimen. Experimental study is carried out by generating the pulsatile flow through pulsatile duplicator. Flow across normal and various severities of stenosis such as 25%, 50% and 75% are studied. Numerical simulation using CFD is also carried out in similar normal and stenosed models. A novel concept of using pulse duplicator to generate pulsatile waves and investigate the different stenosed models has been adopted. Results obtained experimentally and numerically are compared and agree well with that of clinical observations. This study demonstrates significant variation of haemodynamic in post-stenotic region with increased stenosis. Increased pulse pressure, phase lag is observed with increased severity. It is also observed that stenosis greater than 75% is significant as flow complexity is induced with considerable disturbance even in early and latter part of pulse cycle. Such study shall be useful in understanding the flow changes in stenosis and enhance clinical observation. American Scientific Publishers 2016-10 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/54231/1/Experimental%20and%20numerical%20study%20of%20stenotic%20flows%20.pdf Abdul Khader, Shah Mohammed and Adathala, Rajeev and Ayachit, Anurag and Pai, Raghuvir and Vayalappil, Muraleedharan C. and Zuber, Mohammad and Rao, V. R. K. (2016) Experimental and numerical study of stenotic flows. Journal of Medical Imaging and Health Informatics, 6 (6). pp. 1500-1506. ISSN 2156-7018; ESSN: 2156-7026 http://www.ingentaconnect.com/content/asp/jmihi/2016/00000006/00000006/art00025 10.1166/jmihi.2016.1838
institution	Universiti Putra Malaysia
building	UPM Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Putra Malaysia
content_source	UPM Institutional Repository
url_provider	http://psasir.upm.edu.my/
language	English
description	Atherosclerosis has been leading cause of deaths in several countries. Recent technical advances have allowed the investigation of stenotic flows and in understanding the implications with increased severity. Such studies shall provide detailed understanding of flow across stenosis and its progression. In the present study, a large artery representing segment of aorta is considered as test specimen. Experimental study is carried out by generating the pulsatile flow through pulsatile duplicator. Flow across normal and various severities of stenosis such as 25%, 50% and 75% are studied. Numerical simulation using CFD is also carried out in similar normal and stenosed models. A novel concept of using pulse duplicator to generate pulsatile waves and investigate the different stenosed models has been adopted. Results obtained experimentally and numerically are compared and agree well with that of clinical observations. This study demonstrates significant variation of haemodynamic in post-stenotic region with increased stenosis. Increased pulse pressure, phase lag is observed with increased severity. It is also observed that stenosis greater than 75% is significant as flow complexity is induced with considerable disturbance even in early and latter part of pulse cycle. Such study shall be useful in understanding the flow changes in stenosis and enhance clinical observation.
format	Article
author	Abdul Khader, Shah Mohammed Adathala, Rajeev Ayachit, Anurag Pai, Raghuvir Vayalappil, Muraleedharan C. Zuber, Mohammad Rao, V. R. K.
spellingShingle	Abdul Khader, Shah Mohammed Adathala, Rajeev Ayachit, Anurag Pai, Raghuvir Vayalappil, Muraleedharan C. Zuber, Mohammad Rao, V. R. K. Experimental and numerical study of stenotic flows
author_facet	Abdul Khader, Shah Mohammed Adathala, Rajeev Ayachit, Anurag Pai, Raghuvir Vayalappil, Muraleedharan C. Zuber, Mohammad Rao, V. R. K.
author_sort	Abdul Khader, Shah Mohammed
title	Experimental and numerical study of stenotic flows
title_short	Experimental and numerical study of stenotic flows
title_full	Experimental and numerical study of stenotic flows
title_fullStr	Experimental and numerical study of stenotic flows
title_full_unstemmed	Experimental and numerical study of stenotic flows
title_sort	experimental and numerical study of stenotic flows
publisher	American Scientific Publishers
publishDate	2016
url	http://psasir.upm.edu.my/id/eprint/54231/1/Experimental%20and%20numerical%20study%20of%20stenotic%20flows%20.pdf http://psasir.upm.edu.my/id/eprint/54231/ http://www.ingentaconnect.com/content/asp/jmihi/2016/00000006/00000006/art00025
_version_	1643835593943154688
score	13.211869

Experimental and numerical study of stenotic flows

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