Small interfering RNA silencing of interleukin-6 in mesenchymal stromal cells inhibits multiple myeloma cell growth
Studies demonstrated that mesenchymal stromal cells (MSC) from bone marrow stroma produced high concentration of interleukin-6 (IL-6) that promoted multiple myeloma cell growth. In view of the failure of IL-6 monoclonal antibody therapy to demonstrate substantial clinical responses in early clinical...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2016
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| Online Access: | http://psasir.upm.edu.my/id/eprint/53832/1/Small%20interfering%20RNA%20silencing%20of%20interleukin-6%20in%20mesenchymal%20stromal%20cells%20inhibits%20multiple%20myeloma%20cell%20growth.pdf http://psasir.upm.edu.my/id/eprint/53832/ http://www.lrjournal.com/article/S0145-2126(15)30396-9/fulltext |
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