Spontaneous autologous erythrocyte-rosette formation of lymphocytes from cerebrospinal fluid of a dog with canine distemper.

An adult female crossbed dog, with pyrexia, ocular, neurologic and respiratory problems suggestive of distemper, was observed for 28 days. Marked lymphopenia was present on days, 8, 12, and 245, and myoclonus of the fore- and hind-limbs was seen on day 22. At day 24, a cytopahogenic agent with param...

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Main Authors: N. A. B. Y., Cheng, K. M., Tham
Format: Article
Language:English
English
Published: 1991
Online Access:http://psasir.upm.edu.my/id/eprint/5315/1/Spontaneous%20autologous%20erythrocyte.pdf
http://psasir.upm.edu.my/id/eprint/5315/
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spelling my.upm.eprints.53152015-12-22T08:11:50Z http://psasir.upm.edu.my/id/eprint/5315/ Spontaneous autologous erythrocyte-rosette formation of lymphocytes from cerebrospinal fluid of a dog with canine distemper. N. A. B. Y., Cheng K. M., Tham An adult female crossbed dog, with pyrexia, ocular, neurologic and respiratory problems suggestive of distemper, was observed for 28 days. Marked lymphopenia was present on days, 8, 12, and 245, and myoclonus of the fore- and hind-limbs was seen on day 22. At day 24, a cytopahogenic agent with paramyxovirus morphology was isolated from peripheral blood mononuclear cells by co-cultivation with Vero cells. On day 28, cerebrospinal fluid was found to contain 82.7% of lymphocytes and 10% monocytes. About 19% of these lymphocytes formed spontaneous autologous erythrocyte-rosettes. The demonstration of such rosettes (at 4-5 times the level normal for dogs) is unusual. It is possible that is rosette test may be specific for distemper infection. This technique must be further investigated to determine if it can be used as a specific diagnostic test for distemper in dogs. 1991 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/5315/1/Spontaneous%20autologous%20erythrocyte.pdf N. A. B. Y., Cheng and K. M., Tham (1991) Spontaneous autologous erythrocyte-rosette formation of lymphocytes from cerebrospinal fluid of a dog with canine distemper. Jurnal Veterinar Malaysia, 3 (1). pp. 1-6. English
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
English
description An adult female crossbed dog, with pyrexia, ocular, neurologic and respiratory problems suggestive of distemper, was observed for 28 days. Marked lymphopenia was present on days, 8, 12, and 245, and myoclonus of the fore- and hind-limbs was seen on day 22. At day 24, a cytopahogenic agent with paramyxovirus morphology was isolated from peripheral blood mononuclear cells by co-cultivation with Vero cells. On day 28, cerebrospinal fluid was found to contain 82.7% of lymphocytes and 10% monocytes. About 19% of these lymphocytes formed spontaneous autologous erythrocyte-rosettes. The demonstration of such rosettes (at 4-5 times the level normal for dogs) is unusual. It is possible that is rosette test may be specific for distemper infection. This technique must be further investigated to determine if it can be used as a specific diagnostic test for distemper in dogs.
format Article
author N. A. B. Y., Cheng
K. M., Tham
spellingShingle N. A. B. Y., Cheng
K. M., Tham
Spontaneous autologous erythrocyte-rosette formation of lymphocytes from cerebrospinal fluid of a dog with canine distemper.
author_facet N. A. B. Y., Cheng
K. M., Tham
author_sort N. A. B. Y., Cheng
title Spontaneous autologous erythrocyte-rosette formation of lymphocytes from cerebrospinal fluid of a dog with canine distemper.
title_short Spontaneous autologous erythrocyte-rosette formation of lymphocytes from cerebrospinal fluid of a dog with canine distemper.
title_full Spontaneous autologous erythrocyte-rosette formation of lymphocytes from cerebrospinal fluid of a dog with canine distemper.
title_fullStr Spontaneous autologous erythrocyte-rosette formation of lymphocytes from cerebrospinal fluid of a dog with canine distemper.
title_full_unstemmed Spontaneous autologous erythrocyte-rosette formation of lymphocytes from cerebrospinal fluid of a dog with canine distemper.
title_sort spontaneous autologous erythrocyte-rosette formation of lymphocytes from cerebrospinal fluid of a dog with canine distemper.
publishDate 1991
url http://psasir.upm.edu.my/id/eprint/5315/1/Spontaneous%20autologous%20erythrocyte.pdf
http://psasir.upm.edu.my/id/eprint/5315/
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