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Antitrypanosomal activities of selected medicinal plants

The aqueous and ethanolic extracts from four medicinal plants namely Acanthus ilicifolius, Aquilaria malaccensis, Goniothalamus tapis, and Maesa ramentacea, were tested in vitro against Trypanosoma evansi, a hemoprotozoan parasite causing surra in a vast variety of domesticated and wild animals. Th...

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Main Authors: Dyary, Hiewa O., Abdul Kadir, Arifah, Kumar Sharma, Reuben Sunil, Abdullah, Rasedee, Md. Sukari, Mohd Aspollah, Zakaria, Zainul Amiruddin, Ahmad, Zuraini, Somchit, Muhammad Nazrul
Format: Conference or Workshop Item
Language:English
Published: 2012
Online Access:http://psasir.upm.edu.my/id/eprint/50244/1/2-15.pdf
http://psasir.upm.edu.my/id/eprint/50244/
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spelling my.upm.eprints.502442017-03-01T09:38:48Z http://psasir.upm.edu.my/id/eprint/50244/ Antitrypanosomal activities of selected medicinal plants Dyary, Hiewa O. Abdul Kadir, Arifah Kumar Sharma, Reuben Sunil Abdullah, Rasedee Md. Sukari, Mohd Aspollah Zakaria, Zainul Amiruddin Ahmad, Zuraini Somchit, Muhammad Nazrul The aqueous and ethanolic extracts from four medicinal plants namely Acanthus ilicifolius, Aquilaria malaccensis, Goniothalamus tapis, and Maesa ramentacea, were tested in vitro against Trypanosoma evansi, a hemoprotozoan parasite causing surra in a vast variety of domesticated and wild animals. The antitrypanosomal activity was evaluated by calculating median inhibitory concentration (IC50), the concentration that gives half maximal growth of the trypanosomes, of the plant extracts. Goniothalamus tapis ethanolic extract showed the most potent antitrypanosomal activity with an IC50 value of 7.6 ± 1.6 μg ml-1. The other extracts scored IC50 values ranging from 36.2 ± 1.3 μg ml-1 to 314.1 ± 37.1 μg ml-1. 2012 Conference or Workshop Item PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/50244/1/2-15.pdf Dyary, Hiewa O. and Abdul Kadir, Arifah and Kumar Sharma, Reuben Sunil and Abdullah, Rasedee and Md. Sukari, Mohd Aspollah and Zakaria, Zainul Amiruddin and Ahmad, Zuraini and Somchit, Muhammad Nazrul (2012) Antitrypanosomal activities of selected medicinal plants. In: International Conference on One Health and 24th VAM Congress 2012, 21-23 Sept. 2012, Marriott Putrajaya. (pp. 386-388).
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description The aqueous and ethanolic extracts from four medicinal plants namely Acanthus ilicifolius, Aquilaria malaccensis, Goniothalamus tapis, and Maesa ramentacea, were tested in vitro against Trypanosoma evansi, a hemoprotozoan parasite causing surra in a vast variety of domesticated and wild animals. The antitrypanosomal activity was evaluated by calculating median inhibitory concentration (IC50), the concentration that gives half maximal growth of the trypanosomes, of the plant extracts. Goniothalamus tapis ethanolic extract showed the most potent antitrypanosomal activity with an IC50 value of 7.6 ± 1.6 μg ml-1. The other extracts scored IC50 values ranging from 36.2 ± 1.3 μg ml-1 to 314.1 ± 37.1 μg ml-1.
format Conference or Workshop Item
author Dyary, Hiewa O.
Abdul Kadir, Arifah
Kumar Sharma, Reuben Sunil
Abdullah, Rasedee
Md. Sukari, Mohd Aspollah
Zakaria, Zainul Amiruddin
Ahmad, Zuraini
Somchit, Muhammad Nazrul
spellingShingle Dyary, Hiewa O.
Abdul Kadir, Arifah
Kumar Sharma, Reuben Sunil
Abdullah, Rasedee
Md. Sukari, Mohd Aspollah
Zakaria, Zainul Amiruddin
Ahmad, Zuraini
Somchit, Muhammad Nazrul
Antitrypanosomal activities of selected medicinal plants
author_facet Dyary, Hiewa O.
Abdul Kadir, Arifah
Kumar Sharma, Reuben Sunil
Abdullah, Rasedee
Md. Sukari, Mohd Aspollah
Zakaria, Zainul Amiruddin
Ahmad, Zuraini
Somchit, Muhammad Nazrul
author_sort Dyary, Hiewa O.
title Antitrypanosomal activities of selected medicinal plants
title_short Antitrypanosomal activities of selected medicinal plants
title_full Antitrypanosomal activities of selected medicinal plants
title_fullStr Antitrypanosomal activities of selected medicinal plants
title_full_unstemmed Antitrypanosomal activities of selected medicinal plants
title_sort antitrypanosomal activities of selected medicinal plants
publishDate 2012
url http://psasir.upm.edu.my/id/eprint/50244/1/2-15.pdf
http://psasir.upm.edu.my/id/eprint/50244/
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score 13.211869

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