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Thrombosis at unusual sites in reproductive age group: a case series

Thrombosis is one of the causes of morbidity and mortality in women of reproductive age group. Thrombosis at unusual sites may pose diagnostic and management dilemma for health care personnel. Teamwork and good communication provide the best modalities for maximum benefits to patients. Here with, we...

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Main Authors: Mohd Tohit, Eusni Rahayu, Khalid, Bahariah, Seman, Zainina, Md Noor, Sabariah
Format: Article
Language:English
Published: Fakulti Perubatan dan Sains Kesihatan, Universiti Putra Malaysia 2016
Online Access:http://psasir.upm.edu.my/id/eprint/46733/1/FKUSK1_ARTICLE_8.pdf
http://psasir.upm.edu.my/id/eprint/46733/
https://medic.upm.edu.my/jurnal_kami/malaysian_journal_of_medicine_and_health_sciences_mjmhs/mjmhs_vol12_no1_jan_2016-31999
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spelling my.upm.eprints.467332022-07-07T02:42:39Z http://psasir.upm.edu.my/id/eprint/46733/ Thrombosis at unusual sites in reproductive age group: a case series Mohd Tohit, Eusni Rahayu Khalid, Bahariah Seman, Zainina Md Noor, Sabariah Thrombosis is one of the causes of morbidity and mortality in women of reproductive age group. Thrombosis at unusual sites may pose diagnostic and management dilemma for health care personnel. Teamwork and good communication provide the best modalities for maximum benefits to patients. Here with, we presented case a series of thrombosis at unusual sites seen and managed in our clinic. A 35 year-old Malay lady presented with left hemiparesis while she was on oestrogen based combined contraception pills (C-OCP). Imaging studies showed extensive venous thrombosis with bilateral acute cortical infarct. Thrombophilia screening of antiphospholipid syndrome were negative. She was put on anticoagulant and stopped 2 years after the incident. A 40 year-old Malay lady presented with abdominal discomfort, lethargy and massive splenomegaly. Bone marrow and trephine examination revealed primary myelofibrosis with positive JAK2617F. Imaging study showed chronic portal vein thrombosis with portal vein hypertension, complicated by gastro-oesophageal varices. She was put on hydroxyurea and later started on ruxolitinib with banding done over her gastro-oesophageal varices. A 26 year-old Malay lady presented with serositis, mouth ulcer and anaemia symptoms. Laboratory studies were positive for systemic lupus erythematosus and negative for antiphospholipid study. Imaging study showed long segment thrombosis of right internal jugular vein with surrounding subcutaneous oedema. She is currently stable on anticoagulants and steroid. Teamwork and holistic approach is practiced in the investigation and management to provide maximum benefits for patients. Fakulti Perubatan dan Sains Kesihatan, Universiti Putra Malaysia 2016-01 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/46733/1/FKUSK1_ARTICLE_8.pdf Mohd Tohit, Eusni Rahayu and Khalid, Bahariah and Seman, Zainina and Md Noor, Sabariah (2016) Thrombosis at unusual sites in reproductive age group: a case series. Malaysian Journal of Medicine and Health Sciences, 12 (1). pp. 63-66. ISSN 1675-8544 https://medic.upm.edu.my/jurnal_kami/malaysian_journal_of_medicine_and_health_sciences_mjmhs/mjmhs_vol12_no1_jan_2016-31999
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description Thrombosis is one of the causes of morbidity and mortality in women of reproductive age group. Thrombosis at unusual sites may pose diagnostic and management dilemma for health care personnel. Teamwork and good communication provide the best modalities for maximum benefits to patients. Here with, we presented case a series of thrombosis at unusual sites seen and managed in our clinic. A 35 year-old Malay lady presented with left hemiparesis while she was on oestrogen based combined contraception pills (C-OCP). Imaging studies showed extensive venous thrombosis with bilateral acute cortical infarct. Thrombophilia screening of antiphospholipid syndrome were negative. She was put on anticoagulant and stopped 2 years after the incident. A 40 year-old Malay lady presented with abdominal discomfort, lethargy and massive splenomegaly. Bone marrow and trephine examination revealed primary myelofibrosis with positive JAK2617F. Imaging study showed chronic portal vein thrombosis with portal vein hypertension, complicated by gastro-oesophageal varices. She was put on hydroxyurea and later started on ruxolitinib with banding done over her gastro-oesophageal varices. A 26 year-old Malay lady presented with serositis, mouth ulcer and anaemia symptoms. Laboratory studies were positive for systemic lupus erythematosus and negative for antiphospholipid study. Imaging study showed long segment thrombosis of right internal jugular vein with surrounding subcutaneous oedema. She is currently stable on anticoagulants and steroid. Teamwork and holistic approach is practiced in the investigation and management to provide maximum benefits for patients.
format Article
author Mohd Tohit, Eusni Rahayu
Khalid, Bahariah
Seman, Zainina
Md Noor, Sabariah
spellingShingle Mohd Tohit, Eusni Rahayu
Khalid, Bahariah
Seman, Zainina
Md Noor, Sabariah
Thrombosis at unusual sites in reproductive age group: a case series
author_facet Mohd Tohit, Eusni Rahayu
Khalid, Bahariah
Seman, Zainina
Md Noor, Sabariah
author_sort Mohd Tohit, Eusni Rahayu
title Thrombosis at unusual sites in reproductive age group: a case series
title_short Thrombosis at unusual sites in reproductive age group: a case series
title_full Thrombosis at unusual sites in reproductive age group: a case series
title_fullStr Thrombosis at unusual sites in reproductive age group: a case series
title_full_unstemmed Thrombosis at unusual sites in reproductive age group: a case series
title_sort thrombosis at unusual sites in reproductive age group: a case series
publisher Fakulti Perubatan dan Sains Kesihatan, Universiti Putra Malaysia
publishDate 2016
url http://psasir.upm.edu.my/id/eprint/46733/1/FKUSK1_ARTICLE_8.pdf
http://psasir.upm.edu.my/id/eprint/46733/
https://medic.upm.edu.my/jurnal_kami/malaysian_journal_of_medicine_and_health_sciences_mjmhs/mjmhs_vol12_no1_jan_2016-31999
_version_ 1738511945482371072
score 13.211869

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