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Silver@graphene oxide nanocomposite-based optical sensor platform for biomolecules

In this report, a silver@graphene oxide (Ag@GO) nanocomposite-based optical sensor was developed for the detection of biomolecules such as dopamine (DA), ascorbic acid (AA), and uric acid (UA). An aqueous solution of Ag@GO was prepared using a simple chemical reduction method, and it showed a charac...

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Main Authors: Kamali, Khosro Zangeneh, Pandikumar, Alagarsamy, Sivaraman, Gandhi, Lim, Hong Ngee, Wren, Stephen Paul, Tong, Sund, Huang, Nay Ming
Format: Article
Language:English
Published: Royal Society of Chemistry 2015
Online Access:http://psasir.upm.edu.my/id/eprint/46281/1/Silver%40graphene%20oxide%20nanocomposite-based%20optical%20sensor%20platform%20for%20biomolecules.pdf
http://psasir.upm.edu.my/id/eprint/46281/
https://pubs.rsc.org/en/content/articlelanding/2015/ra/c4ra11356j
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spelling my.upm.eprints.462812022-06-17T02:02:51Z http://psasir.upm.edu.my/id/eprint/46281/ Silver@graphene oxide nanocomposite-based optical sensor platform for biomolecules Kamali, Khosro Zangeneh Pandikumar, Alagarsamy Sivaraman, Gandhi Lim, Hong Ngee Wren, Stephen Paul Tong, Sund Huang, Nay Ming In this report, a silver@graphene oxide (Ag@GO) nanocomposite-based optical sensor was developed for the detection of biomolecules such as dopamine (DA), ascorbic acid (AA), and uric acid (UA). An aqueous solution of Ag@GO was prepared using a simple chemical reduction method, and it showed a characteristic surface plasmon resonance (SPR) band at 402 nm. The SPR features of the Ag@GO nanocomposite were used for the detection of DA, AA, and UA. The SPR intensity-based limits of detection (LODs) of DA, AA, and UA were 49 nM, 634 nM, and 927 nM, respectively. The SPR band position-based LODs of DA, AA, and UA were 30 nM, 1.64 μM, and 2.15 μM, respectively. The present optical sensor was more sensitive to DA than to UA and AA. The interactions of the biomolecules with Ag@GO were studied based on density functional theory (DFT), and it was found that DA had more interaction than AA and UA. This novel Ag@GO nanocomposite is simple to prepare and showed excellent stability and sensitivity toward the detection of biomolecules. Royal Society of Chemistry 2015 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/46281/1/Silver%40graphene%20oxide%20nanocomposite-based%20optical%20sensor%20platform%20for%20biomolecules.pdf Kamali, Khosro Zangeneh and Pandikumar, Alagarsamy and Sivaraman, Gandhi and Lim, Hong Ngee and Wren, Stephen Paul and Tong, Sund and Huang, Nay Ming (2015) Silver@graphene oxide nanocomposite-based optical sensor platform for biomolecules. RSC Advances, 5 (23). pp. 17809-17816. ISSN 2046-2069 https://pubs.rsc.org/en/content/articlelanding/2015/ra/c4ra11356j 10.1039/c4ra11356j
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description In this report, a silver@graphene oxide (Ag@GO) nanocomposite-based optical sensor was developed for the detection of biomolecules such as dopamine (DA), ascorbic acid (AA), and uric acid (UA). An aqueous solution of Ag@GO was prepared using a simple chemical reduction method, and it showed a characteristic surface plasmon resonance (SPR) band at 402 nm. The SPR features of the Ag@GO nanocomposite were used for the detection of DA, AA, and UA. The SPR intensity-based limits of detection (LODs) of DA, AA, and UA were 49 nM, 634 nM, and 927 nM, respectively. The SPR band position-based LODs of DA, AA, and UA were 30 nM, 1.64 μM, and 2.15 μM, respectively. The present optical sensor was more sensitive to DA than to UA and AA. The interactions of the biomolecules with Ag@GO were studied based on density functional theory (DFT), and it was found that DA had more interaction than AA and UA. This novel Ag@GO nanocomposite is simple to prepare and showed excellent stability and sensitivity toward the detection of biomolecules.
format Article
author Kamali, Khosro Zangeneh
Pandikumar, Alagarsamy
Sivaraman, Gandhi
Lim, Hong Ngee
Wren, Stephen Paul
Tong, Sund
Huang, Nay Ming
spellingShingle Kamali, Khosro Zangeneh
Pandikumar, Alagarsamy
Sivaraman, Gandhi
Lim, Hong Ngee
Wren, Stephen Paul
Tong, Sund
Huang, Nay Ming
Silver@graphene oxide nanocomposite-based optical sensor platform for biomolecules
author_facet Kamali, Khosro Zangeneh
Pandikumar, Alagarsamy
Sivaraman, Gandhi
Lim, Hong Ngee
Wren, Stephen Paul
Tong, Sund
Huang, Nay Ming
author_sort Kamali, Khosro Zangeneh
title Silver@graphene oxide nanocomposite-based optical sensor platform for biomolecules
title_short Silver@graphene oxide nanocomposite-based optical sensor platform for biomolecules
title_full Silver@graphene oxide nanocomposite-based optical sensor platform for biomolecules
title_fullStr Silver@graphene oxide nanocomposite-based optical sensor platform for biomolecules
title_full_unstemmed Silver@graphene oxide nanocomposite-based optical sensor platform for biomolecules
title_sort silver@graphene oxide nanocomposite-based optical sensor platform for biomolecules
publisher Royal Society of Chemistry
publishDate 2015
url http://psasir.upm.edu.my/id/eprint/46281/1/Silver%40graphene%20oxide%20nanocomposite-based%20optical%20sensor%20platform%20for%20biomolecules.pdf
http://psasir.upm.edu.my/id/eprint/46281/
https://pubs.rsc.org/en/content/articlelanding/2015/ra/c4ra11356j
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score 13.211869

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