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Rapid ferritin iron release using FMN reductase

Iron deficiency anaemia is very common in developing countries and affects approximately two billion people worldwide. To test for iron deficiency, the common practice is to detect the body’s ferritin level using an automated machine. However, ferritin level can be confounded by inflamma...

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Main Authors: Lai, Mei I., Lim, Wai Feng, Yap, Boon Kar, George, Elizabeth, Abdullah, Maha
Format: Article
Language:English
Published: International Academy Publishing 2015
Online Access:http://psasir.upm.edu.my/id/eprint/46079/1/Rapid%20ferritin%20iron%20release%20using%20FMN%20reductase.pdf
http://psasir.upm.edu.my/id/eprint/46079/
http://www.ijbbb.org/show-56-742-1.html
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spelling my.upm.eprints.460792022-03-23T06:24:23Z http://psasir.upm.edu.my/id/eprint/46079/ Rapid ferritin iron release using FMN reductase Lai, Mei I. Lim, Wai Feng Yap, Boon Kar George, Elizabeth Abdullah, Maha Iron deficiency anaemia is very common in developing countries and affects approximately two billion people worldwide. To test for iron deficiency, the common practice is to detect the body’s ferritin level using an automated machine. However, ferritin level can be confounded by inflammation which does not affect the iron level that is available in the ferritin cage. Therefore, we designed a novel assay to achieve rapid ferritin iron release for the detection of iron deficiency anaemia using various biochemical compounds including reducing agents, oxygen scavenger compounds and chaotropic agents. International Academy Publishing 2015 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/46079/1/Rapid%20ferritin%20iron%20release%20using%20FMN%20reductase.pdf Lai, Mei I. and Lim, Wai Feng and Yap, Boon Kar and George, Elizabeth and Abdullah, Maha (2015) Rapid ferritin iron release using FMN reductase. International Journal of Bioscience, Biochemistry and Bioinformatics, 5 (2). pp. 111-119. ISSN 2010-3638 http://www.ijbbb.org/show-56-742-1.html 10.17706/ijbbb.2015.5.2.111-119
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description Iron deficiency anaemia is very common in developing countries and affects approximately two billion people worldwide. To test for iron deficiency, the common practice is to detect the body’s ferritin level using an automated machine. However, ferritin level can be confounded by inflammation which does not affect the iron level that is available in the ferritin cage. Therefore, we designed a novel assay to achieve rapid ferritin iron release for the detection of iron deficiency anaemia using various biochemical compounds including reducing agents, oxygen scavenger compounds and chaotropic agents.
format Article
author Lai, Mei I.
Lim, Wai Feng
Yap, Boon Kar
George, Elizabeth
Abdullah, Maha
spellingShingle Lai, Mei I.
Lim, Wai Feng
Yap, Boon Kar
George, Elizabeth
Abdullah, Maha
Rapid ferritin iron release using FMN reductase
author_facet Lai, Mei I.
Lim, Wai Feng
Yap, Boon Kar
George, Elizabeth
Abdullah, Maha
author_sort Lai, Mei I.
title Rapid ferritin iron release using FMN reductase
title_short Rapid ferritin iron release using FMN reductase
title_full Rapid ferritin iron release using FMN reductase
title_fullStr Rapid ferritin iron release using FMN reductase
title_full_unstemmed Rapid ferritin iron release using FMN reductase
title_sort rapid ferritin iron release using fmn reductase
publisher International Academy Publishing
publishDate 2015
url http://psasir.upm.edu.my/id/eprint/46079/1/Rapid%20ferritin%20iron%20release%20using%20FMN%20reductase.pdf
http://psasir.upm.edu.my/id/eprint/46079/
http://www.ijbbb.org/show-56-742-1.html
_version_ 1729704982282764288
score 13.211869

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