Cover Image

Cytotoxic and antioxidant properties of Borneo Garcinia species (Clusiaceae)

There are several local Malaysian Garcinia species which have ethnobotanical uses but so far very few studies have been carried out to link these folkloric uses with the phytochemistry of these plant species. It would be interesting therefore, to develop phytochemical data of two such Sarawakian spe...

Full description

Saved in:
Bibliographic Details
Main Authors: Khong, Heng Yen, Jong, Vivien Yi Mian, Ee, Gwendoline Cheng Lian
Format: Conference or Workshop Item
Language:English
Published: IEEE 2011
Online Access:http://psasir.upm.edu.my/id/eprint/45286/1/Cytotoxic%20and%20antioxidant%20properties%20of%20Borneo%20Garcinia%20species%20%28Clusiaceae%29.pdf
http://psasir.upm.edu.my/id/eprint/45286/
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.upm.eprints.45286
record_format eprints
spelling my.upm.eprints.452862020-08-05T06:48:13Z http://psasir.upm.edu.my/id/eprint/45286/ Cytotoxic and antioxidant properties of Borneo Garcinia species (Clusiaceae) Khong, Heng Yen Jong, Vivien Yi Mian Ee, Gwendoline Cheng Lian There are several local Malaysian Garcinia species which have ethnobotanical uses but so far very few studies have been carried out to link these folkloric uses with the phytochemistry of these plant species. It would be interesting therefore, to develop phytochemical data of two such Sarawakian species which are Garcinia eugenifolia and Garcinia nitida which have not been reported before. The methanol extract from the G. eugenifolia leaves exhibited moderate antioxidant activity with EC50 values of 66 and 51 respectively, when compared to ascorbic acid with EC50 values of 15.32 μg/mL. This crude also showed weak cytotoxic activity to HeLa with IC50 values of 71 and 40 μg/mL respectively. However, the leaves extracts of G. nitida showed good cytotoxic activity with IC50 values of 4 and 7 μg/mL respectively towards both cell lines. IEEE 2011 Conference or Workshop Item PeerReviewed text en http://psasir.upm.edu.my/id/eprint/45286/1/Cytotoxic%20and%20antioxidant%20properties%20of%20Borneo%20Garcinia%20species%20%28Clusiaceae%29.pdf Khong, Heng Yen and Jong, Vivien Yi Mian and Ee, Gwendoline Cheng Lian (2011) Cytotoxic and antioxidant properties of Borneo Garcinia species (Clusiaceae). In: 2011 IEEE Colloquium on Humanities, Science and Engineering (CHUSER 2011), 5-6 Dec. 2011, Penang, Malaysia. (pp. 831-833). 10.1109/CHUSER.2011.6163853
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description There are several local Malaysian Garcinia species which have ethnobotanical uses but so far very few studies have been carried out to link these folkloric uses with the phytochemistry of these plant species. It would be interesting therefore, to develop phytochemical data of two such Sarawakian species which are Garcinia eugenifolia and Garcinia nitida which have not been reported before. The methanol extract from the G. eugenifolia leaves exhibited moderate antioxidant activity with EC50 values of 66 and 51 respectively, when compared to ascorbic acid with EC50 values of 15.32 μg/mL. This crude also showed weak cytotoxic activity to HeLa with IC50 values of 71 and 40 μg/mL respectively. However, the leaves extracts of G. nitida showed good cytotoxic activity with IC50 values of 4 and 7 μg/mL respectively towards both cell lines.
format Conference or Workshop Item
author Khong, Heng Yen
Jong, Vivien Yi Mian
Ee, Gwendoline Cheng Lian
spellingShingle Khong, Heng Yen
Jong, Vivien Yi Mian
Ee, Gwendoline Cheng Lian
Cytotoxic and antioxidant properties of Borneo Garcinia species (Clusiaceae)
author_facet Khong, Heng Yen
Jong, Vivien Yi Mian
Ee, Gwendoline Cheng Lian
author_sort Khong, Heng Yen
title Cytotoxic and antioxidant properties of Borneo Garcinia species (Clusiaceae)
title_short Cytotoxic and antioxidant properties of Borneo Garcinia species (Clusiaceae)
title_full Cytotoxic and antioxidant properties of Borneo Garcinia species (Clusiaceae)
title_fullStr Cytotoxic and antioxidant properties of Borneo Garcinia species (Clusiaceae)
title_full_unstemmed Cytotoxic and antioxidant properties of Borneo Garcinia species (Clusiaceae)
title_sort cytotoxic and antioxidant properties of borneo garcinia species (clusiaceae)
publisher IEEE
publishDate 2011
url http://psasir.upm.edu.my/id/eprint/45286/1/Cytotoxic%20and%20antioxidant%20properties%20of%20Borneo%20Garcinia%20species%20%28Clusiaceae%29.pdf
http://psasir.upm.edu.my/id/eprint/45286/
_version_ 1675328729543344128
score 13.211869

Similar Items