Cofactor strap regulates oxidative phosphorylation and mitochondrial p53 activity through ATP synthase
Metabolic reprogramming is a hallmark of cancer cells. Strap (stress-responsive activator of p300) is a novel TPR motif OB-fold protein that contributes to p53 transcriptional activation. We show here that, in addition to its established transcriptional role, Strap is localised at mitochondria where...
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| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2015
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| Online Access: | http://psasir.upm.edu.my/id/eprint/44087/1/Cofactor%20strap%20regulates%20oxidative%20phosphorylation%20and%20mitochondrial%20p53%20activity%20through%20ATP%20synthase.pdf http://psasir.upm.edu.my/id/eprint/44087/ https://www.nature.com/articles/cdd2014135 |
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