Cover Image

Adaptational properties and applications of cold-active lipase from psychrophilic bacteria

Psychrophilic microorganisms are cold-adapted with distinct properties from other thermal classes thriving in cold conditions in large areas of the earth's cold environment. Maintenance of functional membranes, evolving cold-adapted enzymes and synthesizing a range of structural features are ba...

Full description

Saved in:
Bibliographic Details
Main Authors: Maiangwa, Jonathan, Mohamad Ali, Mohd Shukuri, Salleh, Abu Bakar, Raja Abdul Rahman, Raja Noor Zaliha, Mohd Shariff, Fairolniza, Leow, Thean Chor
Format: Article
Language:English
Published: Springer 2015
Online Access:http://psasir.upm.edu.my/id/eprint/43657/1/Adaptational%20properties%20and.pdf
http://psasir.upm.edu.my/id/eprint/43657/
http://link.springer.com/article/10.1007/s00792-014-0710-5
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.upm.eprints.43657
record_format eprints
spelling my.upm.eprints.436572016-08-08T03:21:27Z http://psasir.upm.edu.my/id/eprint/43657/ Adaptational properties and applications of cold-active lipase from psychrophilic bacteria Maiangwa, Jonathan Mohamad Ali, Mohd Shukuri Salleh, Abu Bakar Raja Abdul Rahman, Raja Noor Zaliha Mohd Shariff, Fairolniza Leow, Thean Chor Psychrophilic microorganisms are cold-adapted with distinct properties from other thermal classes thriving in cold conditions in large areas of the earth's cold environment. Maintenance of functional membranes, evolving cold-adapted enzymes and synthesizing a range of structural features are basic adaptive strategies of psychrophiles. Among the cold-evolved enzymes are the cold-active lipases, a group of microbial lipases with inherent stability-activity-flexibility property that have engaged the interest of researchers over the years. Current knowledge regarding these cold-evolved enzymes in psychrophilic bacteria proves a display of high catalytic efficiency with low thermal stability, which is a differentiating feature with that of their mesophilic and thermophilic counterparts. Improvement strategies of their adaptive structural features have significantly benefited the enzyme industry. Based on their homogeneity and purity, molecular characterizations of these enzymes have been successful and their properties make them unique biocatalysts for various industrial and biotechnological applications. Although, strong association of lipopolysaccharides from Antarctic microorganisms with lipid hydrolases pose a challenge in their purification, heterologous expression of the cold-adapted lipases with affinity tags simplifies purification with higher yield. The review discusses these cold-evolved lipases from bacteria and their peculiar properties, in addition to their potential biotechnological and industrial applications. Springer 2015 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/43657/1/Adaptational%20properties%20and.pdf Maiangwa, Jonathan and Mohamad Ali, Mohd Shukuri and Salleh, Abu Bakar and Raja Abdul Rahman, Raja Noor Zaliha and Mohd Shariff, Fairolniza and Leow, Thean Chor (2015) Adaptational properties and applications of cold-active lipase from psychrophilic bacteria. Extremophiles, 19 (2). pp. 235-247. ISSN 1431-0651; ESSN: 1433-4909 http://link.springer.com/article/10.1007/s00792-014-0710-5 10.1007/s00792-014-0710-5
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description Psychrophilic microorganisms are cold-adapted with distinct properties from other thermal classes thriving in cold conditions in large areas of the earth's cold environment. Maintenance of functional membranes, evolving cold-adapted enzymes and synthesizing a range of structural features are basic adaptive strategies of psychrophiles. Among the cold-evolved enzymes are the cold-active lipases, a group of microbial lipases with inherent stability-activity-flexibility property that have engaged the interest of researchers over the years. Current knowledge regarding these cold-evolved enzymes in psychrophilic bacteria proves a display of high catalytic efficiency with low thermal stability, which is a differentiating feature with that of their mesophilic and thermophilic counterparts. Improvement strategies of their adaptive structural features have significantly benefited the enzyme industry. Based on their homogeneity and purity, molecular characterizations of these enzymes have been successful and their properties make them unique biocatalysts for various industrial and biotechnological applications. Although, strong association of lipopolysaccharides from Antarctic microorganisms with lipid hydrolases pose a challenge in their purification, heterologous expression of the cold-adapted lipases with affinity tags simplifies purification with higher yield. The review discusses these cold-evolved lipases from bacteria and their peculiar properties, in addition to their potential biotechnological and industrial applications.
format Article
author Maiangwa, Jonathan
Mohamad Ali, Mohd Shukuri
Salleh, Abu Bakar
Raja Abdul Rahman, Raja Noor Zaliha
Mohd Shariff, Fairolniza
Leow, Thean Chor
spellingShingle Maiangwa, Jonathan
Mohamad Ali, Mohd Shukuri
Salleh, Abu Bakar
Raja Abdul Rahman, Raja Noor Zaliha
Mohd Shariff, Fairolniza
Leow, Thean Chor
Adaptational properties and applications of cold-active lipase from psychrophilic bacteria
author_facet Maiangwa, Jonathan
Mohamad Ali, Mohd Shukuri
Salleh, Abu Bakar
Raja Abdul Rahman, Raja Noor Zaliha
Mohd Shariff, Fairolniza
Leow, Thean Chor
author_sort Maiangwa, Jonathan
title Adaptational properties and applications of cold-active lipase from psychrophilic bacteria
title_short Adaptational properties and applications of cold-active lipase from psychrophilic bacteria
title_full Adaptational properties and applications of cold-active lipase from psychrophilic bacteria
title_fullStr Adaptational properties and applications of cold-active lipase from psychrophilic bacteria
title_full_unstemmed Adaptational properties and applications of cold-active lipase from psychrophilic bacteria
title_sort adaptational properties and applications of cold-active lipase from psychrophilic bacteria
publisher Springer
publishDate 2015
url http://psasir.upm.edu.my/id/eprint/43657/1/Adaptational%20properties%20and.pdf
http://psasir.upm.edu.my/id/eprint/43657/
http://link.springer.com/article/10.1007/s00792-014-0710-5
_version_ 1643833630442651648
score 13.211869

Similar Items