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A review on bioinformatics enrichment analysis tools towards functional analysis of high throughput gene set data

The emergence of high throughput data in genomic, proteomic and bioinformatics has increased the necessity to develop large amount of functional analysis tools to facilitate the inference of biologically meaningful data. A promising high throughput strategy, which is the gene-annotation enrichment a...

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Main Authors: Shi, Jing Lu, Muzaffar Shah, Farah Fathiah, Mohamad, Mohd Saberi, Moorthy, Kohbalan, Deris, Safaai, Zakaria, Zalmiyah, Napis, Suhaimi
Format: Article
Language:English
Published: Bentham Science Publishers 2015
Online Access:http://psasir.upm.edu.my/id/eprint/43575/1/A%20review%20on%20bioinformatics%20enrichment%20analysis%20tools%20towards%20functional%20analysis%20of%20high%20throughput%20gene%20set%20data.pdf
http://psasir.upm.edu.my/id/eprint/43575/
http://benthamscience.com/journals/current-proteomics/volume/12/issue/1/page/14/
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spelling my.upm.eprints.435752016-07-21T04:52:42Z http://psasir.upm.edu.my/id/eprint/43575/ A review on bioinformatics enrichment analysis tools towards functional analysis of high throughput gene set data Shi, Jing Lu Muzaffar Shah, Farah Fathiah Mohamad, Mohd Saberi Moorthy, Kohbalan Deris, Safaai Zakaria, Zalmiyah Napis, Suhaimi The emergence of high throughput data in genomic, proteomic and bioinformatics has increased the necessity to develop large amount of functional analysis tools to facilitate the inference of biologically meaningful data. A promising high throughput strategy, which is the gene-annotation enrichment analysis, can increase the elucidation ability of related biological processes. This paper reviews 35 bioinformatics enrichment tools and 5 gene set databases that are currently available in the field, which include the description of these tools and databases. This information can help tool developers and users to gain a broad view and better understanding on the bioinformatics enrichment tools and databases, enabling a better decision making in choosing tools in particular research interest. Bentham Science Publishers 2015 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/43575/1/A%20review%20on%20bioinformatics%20enrichment%20analysis%20tools%20towards%20functional%20analysis%20of%20high%20throughput%20gene%20set%20data.pdf Shi, Jing Lu and Muzaffar Shah, Farah Fathiah and Mohamad, Mohd Saberi and Moorthy, Kohbalan and Deris, Safaai and Zakaria, Zalmiyah and Napis, Suhaimi (2015) A review on bioinformatics enrichment analysis tools towards functional analysis of high throughput gene set data. Current Proteomics, 12 (1). pp. 14-27. ISSN 1570-1646; ESSN: 1875-6247 http://benthamscience.com/journals/current-proteomics/volume/12/issue/1/page/14/ 10.2174/157016461201150506200927
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description The emergence of high throughput data in genomic, proteomic and bioinformatics has increased the necessity to develop large amount of functional analysis tools to facilitate the inference of biologically meaningful data. A promising high throughput strategy, which is the gene-annotation enrichment analysis, can increase the elucidation ability of related biological processes. This paper reviews 35 bioinformatics enrichment tools and 5 gene set databases that are currently available in the field, which include the description of these tools and databases. This information can help tool developers and users to gain a broad view and better understanding on the bioinformatics enrichment tools and databases, enabling a better decision making in choosing tools in particular research interest.
format Article
author Shi, Jing Lu
Muzaffar Shah, Farah Fathiah
Mohamad, Mohd Saberi
Moorthy, Kohbalan
Deris, Safaai
Zakaria, Zalmiyah
Napis, Suhaimi
spellingShingle Shi, Jing Lu
Muzaffar Shah, Farah Fathiah
Mohamad, Mohd Saberi
Moorthy, Kohbalan
Deris, Safaai
Zakaria, Zalmiyah
Napis, Suhaimi
A review on bioinformatics enrichment analysis tools towards functional analysis of high throughput gene set data
author_facet Shi, Jing Lu
Muzaffar Shah, Farah Fathiah
Mohamad, Mohd Saberi
Moorthy, Kohbalan
Deris, Safaai
Zakaria, Zalmiyah
Napis, Suhaimi
author_sort Shi, Jing Lu
title A review on bioinformatics enrichment analysis tools towards functional analysis of high throughput gene set data
title_short A review on bioinformatics enrichment analysis tools towards functional analysis of high throughput gene set data
title_full A review on bioinformatics enrichment analysis tools towards functional analysis of high throughput gene set data
title_fullStr A review on bioinformatics enrichment analysis tools towards functional analysis of high throughput gene set data
title_full_unstemmed A review on bioinformatics enrichment analysis tools towards functional analysis of high throughput gene set data
title_sort review on bioinformatics enrichment analysis tools towards functional analysis of high throughput gene set data
publisher Bentham Science Publishers
publishDate 2015
url http://psasir.upm.edu.my/id/eprint/43575/1/A%20review%20on%20bioinformatics%20enrichment%20analysis%20tools%20towards%20functional%20analysis%20of%20high%20throughput%20gene%20set%20data.pdf
http://psasir.upm.edu.my/id/eprint/43575/
http://benthamscience.com/journals/current-proteomics/volume/12/issue/1/page/14/
_version_ 1643833606370492416
score 13.211869

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