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Antioxidant and antiacetylcholinesterase activities of Pluchea indica Less

This study was undertaken to evaluate the antioxidant and acetylcholinesterase inhibition properties of stems and leaf of hexane and methanolic extracts of Pluchea indica. Methanolic extract of leaves showed the highest antioxidant activity (IC50= 24.45 ± 0.34 μg/ml) and total phenolic contents (573...

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Main Authors: Ab. Rahim, Noridayu, Hii, Yueh Feng, Abas, Faridah, Shaari, Khozirah, Lajis, Nordin
Format: Article
Language:English
Published: Faculty of Food Science and Technology, Universiti Putra Malaysia 2011
Online Access:http://psasir.upm.edu.my/id/eprint/40678/1/Antioxidant%20and%20antiacetylcholinesterase%20activities%20of%20Pluchea%20indica%20Less..pdf
http://psasir.upm.edu.my/id/eprint/40678/
http://www.ifrj.upm.edu.my/18%20%2803%29%202011/%2810%29IFRJ-2010-294.pdf
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spelling my.upm.eprints.406782015-11-27T02:52:22Z http://psasir.upm.edu.my/id/eprint/40678/ Antioxidant and antiacetylcholinesterase activities of Pluchea indica Less Ab. Rahim, Noridayu Hii, Yueh Feng Abas, Faridah Shaari, Khozirah Lajis, Nordin This study was undertaken to evaluate the antioxidant and acetylcholinesterase inhibition properties of stems and leaf of hexane and methanolic extracts of Pluchea indica. Methanolic extract of leaves showed the highest antioxidant activity (IC50= 24.45 ± 0.34 μg/ml) and total phenolic contents (573.52 ± 6.2 mg GAE/100 g crude extract), in DPPH radical scavenging and Folin-Ciocalteu assays respectively, however, it failed to inhibit acetylcholinesterase in TLC bioautographic detection. The rest of plant extracts, included methanolic extract of stems, hexane extract of both leaves and stems, were detected to have acetylcholinesterase inhibitory properties. Hexane extract of both leaves and stems exhibited lower or negligible level of antioxidant activity and phenolic contents. Pluchea indica may provide a potential natural source of bioactive compounds, and maybe beneficial to the human health. Faculty of Food Science and Technology, Universiti Putra Malaysia 2011 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/40678/1/Antioxidant%20and%20antiacetylcholinesterase%20activities%20of%20Pluchea%20indica%20Less..pdf Ab. Rahim, Noridayu and Hii, Yueh Feng and Abas, Faridah and Shaari, Khozirah and Lajis, Nordin (2011) Antioxidant and antiacetylcholinesterase activities of Pluchea indica Less. International Food Research Journal, 18 (3). pp. 925-929. ISSN 1985-4668; ESSN: 2231-7546 http://www.ifrj.upm.edu.my/18%20%2803%29%202011/%2810%29IFRJ-2010-294.pdf
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description This study was undertaken to evaluate the antioxidant and acetylcholinesterase inhibition properties of stems and leaf of hexane and methanolic extracts of Pluchea indica. Methanolic extract of leaves showed the highest antioxidant activity (IC50= 24.45 ± 0.34 μg/ml) and total phenolic contents (573.52 ± 6.2 mg GAE/100 g crude extract), in DPPH radical scavenging and Folin-Ciocalteu assays respectively, however, it failed to inhibit acetylcholinesterase in TLC bioautographic detection. The rest of plant extracts, included methanolic extract of stems, hexane extract of both leaves and stems, were detected to have acetylcholinesterase inhibitory properties. Hexane extract of both leaves and stems exhibited lower or negligible level of antioxidant activity and phenolic contents. Pluchea indica may provide a potential natural source of bioactive compounds, and maybe beneficial to the human health.
format Article
author Ab. Rahim, Noridayu
Hii, Yueh Feng
Abas, Faridah
Shaari, Khozirah
Lajis, Nordin
spellingShingle Ab. Rahim, Noridayu
Hii, Yueh Feng
Abas, Faridah
Shaari, Khozirah
Lajis, Nordin
Antioxidant and antiacetylcholinesterase activities of Pluchea indica Less
author_facet Ab. Rahim, Noridayu
Hii, Yueh Feng
Abas, Faridah
Shaari, Khozirah
Lajis, Nordin
author_sort Ab. Rahim, Noridayu
title Antioxidant and antiacetylcholinesterase activities of Pluchea indica Less
title_short Antioxidant and antiacetylcholinesterase activities of Pluchea indica Less
title_full Antioxidant and antiacetylcholinesterase activities of Pluchea indica Less
title_fullStr Antioxidant and antiacetylcholinesterase activities of Pluchea indica Less
title_full_unstemmed Antioxidant and antiacetylcholinesterase activities of Pluchea indica Less
title_sort antioxidant and antiacetylcholinesterase activities of pluchea indica less
publisher Faculty of Food Science and Technology, Universiti Putra Malaysia
publishDate 2011
url http://psasir.upm.edu.my/id/eprint/40678/1/Antioxidant%20and%20antiacetylcholinesterase%20activities%20of%20Pluchea%20indica%20Less..pdf
http://psasir.upm.edu.my/id/eprint/40678/
http://www.ifrj.upm.edu.my/18%20%2803%29%202011/%2810%29IFRJ-2010-294.pdf
_version_ 1643832785470750720
score 13.211869

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