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Antimicrobial therapy and bacterial resistance: a pilot survey

It was only about 40 years ago that tuberculosis, cholera, scarlet fever, syphilis and pneumonia, which were the leading infectious diseases causing death on a worldwide basis were effectively treated with antibiotics. Since that time the frequent and often indiscriminate use of antimicrobial agents...

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Main Authors: Abdullah, A. Salam, Baggot, J. Desmond, Too, H. L.
Format: Article
Language:English
Published: Malaysian Society of Applied Biology 1986
Online Access:http://psasir.upm.edu.my/id/eprint/39775/1/Aug%208%20-%20Antimicrobial%20therapy%20and%20bacterial%20resistance%20a%20pilot%20survey.pdf
http://psasir.upm.edu.my/id/eprint/39775/
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spelling my.upm.eprints.397752015-09-22T03:19:18Z http://psasir.upm.edu.my/id/eprint/39775/ Antimicrobial therapy and bacterial resistance: a pilot survey Abdullah, A. Salam Baggot, J. Desmond Too, H. L. It was only about 40 years ago that tuberculosis, cholera, scarlet fever, syphilis and pneumonia, which were the leading infectious diseases causing death on a worldwide basis were effectively treated with antibiotics. Since that time the frequent and often indiscriminate use of antimicrobial agents in medical practice, both human and veterinary, has resulted in the widespread development of bacterial resistance. Transferable drug resistance factors were first demonstrated in Shigella by Ochiai et al. (1959) and independently by Akiba et al. (1960). Over the years it has repeatedly been inferred, often without conclusive evidence, that resistance bacteria originating from food-producing animals were responsible for sudden outbreaks of "difficult to treat" infections in humans. AI. though the extent to which this is true cannot be determined, it is generally accepted that resistant bacterial strains of animal origin can reach humans in contaminated food products. It is strongly suspected that the use of antibiotics as growth promotants, given continuously in the feed, has facilitated the development of resistant bacterial strains in farm animals. Two independent studies carried out in preantibiotic communities have presented evidence that R factor evolved before the advent of the antibiotic era (Davis and Anandan, 1970; Gardner et al., 1969). This interesting finding does not diminish the contribution of frequent antibiotic usage to the development of bacterial resistance. Malaysian Society of Applied Biology 1986 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/39775/1/Aug%208%20-%20Antimicrobial%20therapy%20and%20bacterial%20resistance%20a%20pilot%20survey.pdf Abdullah, A. Salam and Baggot, J. Desmond and Too, H. L. (1986) Antimicrobial therapy and bacterial resistance: a pilot survey. Malaysian Applied Biology, 15 (2). pp. 183-185. ISSN 0126-8643
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description It was only about 40 years ago that tuberculosis, cholera, scarlet fever, syphilis and pneumonia, which were the leading infectious diseases causing death on a worldwide basis were effectively treated with antibiotics. Since that time the frequent and often indiscriminate use of antimicrobial agents in medical practice, both human and veterinary, has resulted in the widespread development of bacterial resistance. Transferable drug resistance factors were first demonstrated in Shigella by Ochiai et al. (1959) and independently by Akiba et al. (1960). Over the years it has repeatedly been inferred, often without conclusive evidence, that resistance bacteria originating from food-producing animals were responsible for sudden outbreaks of "difficult to treat" infections in humans. AI. though the extent to which this is true cannot be determined, it is generally accepted that resistant bacterial strains of animal origin can reach humans in contaminated food products. It is strongly suspected that the use of antibiotics as growth promotants, given continuously in the feed, has facilitated the development of resistant bacterial strains in farm animals. Two independent studies carried out in preantibiotic communities have presented evidence that R factor evolved before the advent of the antibiotic era (Davis and Anandan, 1970; Gardner et al., 1969). This interesting finding does not diminish the contribution of frequent antibiotic usage to the development of bacterial resistance.
format Article
author Abdullah, A. Salam
Baggot, J. Desmond
Too, H. L.
spellingShingle Abdullah, A. Salam
Baggot, J. Desmond
Too, H. L.
Antimicrobial therapy and bacterial resistance: a pilot survey
author_facet Abdullah, A. Salam
Baggot, J. Desmond
Too, H. L.
author_sort Abdullah, A. Salam
title Antimicrobial therapy and bacterial resistance: a pilot survey
title_short Antimicrobial therapy and bacterial resistance: a pilot survey
title_full Antimicrobial therapy and bacterial resistance: a pilot survey
title_fullStr Antimicrobial therapy and bacterial resistance: a pilot survey
title_full_unstemmed Antimicrobial therapy and bacterial resistance: a pilot survey
title_sort antimicrobial therapy and bacterial resistance: a pilot survey
publisher Malaysian Society of Applied Biology
publishDate 1986
url http://psasir.upm.edu.my/id/eprint/39775/1/Aug%208%20-%20Antimicrobial%20therapy%20and%20bacterial%20resistance%20a%20pilot%20survey.pdf
http://psasir.upm.edu.my/id/eprint/39775/
_version_ 1643832520573190144
score 13.211869

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