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Microencapsulated tuna oil results in higher absorption of DHA in toddlers

Docosahexaenoic acid (DHA) is an essential component for brain and visual acuity development during foetal and early postnatal life. A newly released directive under the European Commission stipulates DHA as a mandatory ingredient in infant formula. This poses challenges to manufacturers in preservi...

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Main Authors: Fard, Samaneh Ghasemi, Loh, Su Peng, Turchini, Giovanni M., Bo, Wang, Elliott, Glenn, Sinclair, Andrew J.
Format: Article
Language:English
Published: MDPI 2020
Online Access:http://psasir.upm.edu.my/id/eprint/38179/1/38179.pdf
http://psasir.upm.edu.my/id/eprint/38179/
https://www.mdpi.com/2072-6643/12/1/248
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spelling my.upm.eprints.381792020-05-03T23:03:42Z http://psasir.upm.edu.my/id/eprint/38179/ Microencapsulated tuna oil results in higher absorption of DHA in toddlers Fard, Samaneh Ghasemi Loh, Su Peng Turchini, Giovanni M. Bo, Wang Elliott, Glenn Sinclair, Andrew J. Docosahexaenoic acid (DHA) is an essential component for brain and visual acuity development during foetal and early postnatal life. A newly released directive under the European Commission stipulates DHA as a mandatory ingredient in infant formula. This poses challenges to manufacturers in preserving the stability and bioavailability of DHA at levels akin to human breast milk. The aims of this study were (a) to investigate the bioavailability of microencapsulated omega-3 DHA formulations in healthy toddlers compared with high DHA fish oil for a one-month period and (b) to assess the effect of DHA supplementation on children’s sleep and cry patterns. Sixty toddlers were randomly allocated to four groups: 1. unfortified formula, 2. unfortified formula plus high DHA tuna oil, 3. fortified formula with dairy-based microencapsulated high DHA tuna oil powder, and 4. fortified formula with allergenic-free microencapsulated high DHA tuna oil powder. Bioavailability was assessed from both blood and faecal fatty acid levels. The results showed an enhanced bioavailability with significantly greater concentrations of blood DHA levels in formulas with microencapsulated powders. There were no significant effects of treatment on sleep and cry patterns. Application and delivery of microencapsulated DHA tuna oil powder in toddlers’ formula provided better bioavailability of the active DHA. MDPI 2020 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/38179/1/38179.pdf Fard, Samaneh Ghasemi and Loh, Su Peng and Turchini, Giovanni M. and Bo, Wang and Elliott, Glenn and Sinclair, Andrew J. (2020) Microencapsulated tuna oil results in higher absorption of DHA in toddlers. Nutrients, 12 (1). art. no. 248. pp. 1-15. ISSN 2072-6643 https://www.mdpi.com/2072-6643/12/1/248 10.3390/nu12010248
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description Docosahexaenoic acid (DHA) is an essential component for brain and visual acuity development during foetal and early postnatal life. A newly released directive under the European Commission stipulates DHA as a mandatory ingredient in infant formula. This poses challenges to manufacturers in preserving the stability and bioavailability of DHA at levels akin to human breast milk. The aims of this study were (a) to investigate the bioavailability of microencapsulated omega-3 DHA formulations in healthy toddlers compared with high DHA fish oil for a one-month period and (b) to assess the effect of DHA supplementation on children’s sleep and cry patterns. Sixty toddlers were randomly allocated to four groups: 1. unfortified formula, 2. unfortified formula plus high DHA tuna oil, 3. fortified formula with dairy-based microencapsulated high DHA tuna oil powder, and 4. fortified formula with allergenic-free microencapsulated high DHA tuna oil powder. Bioavailability was assessed from both blood and faecal fatty acid levels. The results showed an enhanced bioavailability with significantly greater concentrations of blood DHA levels in formulas with microencapsulated powders. There were no significant effects of treatment on sleep and cry patterns. Application and delivery of microencapsulated DHA tuna oil powder in toddlers’ formula provided better bioavailability of the active DHA.
format Article
author Fard, Samaneh Ghasemi
Loh, Su Peng
Turchini, Giovanni M.
Bo, Wang
Elliott, Glenn
Sinclair, Andrew J.
spellingShingle Fard, Samaneh Ghasemi
Loh, Su Peng
Turchini, Giovanni M.
Bo, Wang
Elliott, Glenn
Sinclair, Andrew J.
Microencapsulated tuna oil results in higher absorption of DHA in toddlers
author_facet Fard, Samaneh Ghasemi
Loh, Su Peng
Turchini, Giovanni M.
Bo, Wang
Elliott, Glenn
Sinclair, Andrew J.
author_sort Fard, Samaneh Ghasemi
title Microencapsulated tuna oil results in higher absorption of DHA in toddlers
title_short Microencapsulated tuna oil results in higher absorption of DHA in toddlers
title_full Microencapsulated tuna oil results in higher absorption of DHA in toddlers
title_fullStr Microencapsulated tuna oil results in higher absorption of DHA in toddlers
title_full_unstemmed Microencapsulated tuna oil results in higher absorption of DHA in toddlers
title_sort microencapsulated tuna oil results in higher absorption of dha in toddlers
publisher MDPI
publishDate 2020
url http://psasir.upm.edu.my/id/eprint/38179/1/38179.pdf
http://psasir.upm.edu.my/id/eprint/38179/
https://www.mdpi.com/2072-6643/12/1/248
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score 13.211869

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