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A rare case of acute psychosis as an isolated manifestation of extrapontine myelinolysis

Aims and Background: Central pontine myelinolysis (CPM) and extrapontine myelinolysis (EPM) are recognized as osmotic demyelination syndrome (ODS). ODS is pathologically characterized by non-inflammatory demyelination of several brain structures with sparing of axons. This condition is usually assoc...

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Main Authors: Wan Sulaiman, Wan Aliaa, Hoo, Fan Kee, Basri, Hamidon, Hasan, Shariful, Mohd Sazlly Lim, Sazlyna, Foo, Yoke Loong, Ching, Siew Mooi, Vasudevan, Ramachandran, Mohamed, Mohd Hazmi, Hashim, Hasnur Zaman
Format: Article
Language:English
Published: Sciencedomain International 2014
Online Access:http://psasir.upm.edu.my/id/eprint/36246/1/A%20rare%20case%20of%20acute%20psychosis%20as%20an%20isolated%20manifestation%20of%20extrapontine%20myelinolysis.pdf
http://psasir.upm.edu.my/id/eprint/36246/
http://www.sciencedomain.org/abstract.php?iid=480&id=12&aid=4294
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spelling my.upm.eprints.362462015-10-09T00:43:16Z http://psasir.upm.edu.my/id/eprint/36246/ A rare case of acute psychosis as an isolated manifestation of extrapontine myelinolysis Wan Sulaiman, Wan Aliaa Hoo, Fan Kee Basri, Hamidon Hasan, Shariful Mohd Sazlly Lim, Sazlyna Foo, Yoke Loong Ching, Siew Mooi Vasudevan, Ramachandran Mohamed, Mohd Hazmi Hashim, Hasnur Zaman Aims and Background: Central pontine myelinolysis (CPM) and extrapontine myelinolysis (EPM) are recognized as osmotic demyelination syndrome (ODS). ODS is pathologically characterized by non-inflammatory demyelination of several brain structures with sparing of axons. This condition is usually associated with overzealous correction of hyponatraemia. Acute psychosis as the sole clinical manifestation is extremely rare. Presentation of Case: Hence, we report an interesting case of a middle-aged man who was diagnosed with EPM, following rapid correction of hyponatraemia and subsequently developed acute psychosis. He made a good recovery with supportive treatment alone. Discussion and Conclusion: The possibility of psychosis as a manifestation of ODS, particularly in patients with recent correction of hyponatraemia. The rate of correction of plasma sodium level is the key point for preventing ODS and its complications. Sciencedomain International 2014 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/36246/1/A%20rare%20case%20of%20acute%20psychosis%20as%20an%20isolated%20manifestation%20of%20extrapontine%20myelinolysis.pdf Wan Sulaiman, Wan Aliaa and Hoo, Fan Kee and Basri, Hamidon and Hasan, Shariful and Mohd Sazlly Lim, Sazlyna and Foo, Yoke Loong and Ching, Siew Mooi and Vasudevan, Ramachandran and Mohamed, Mohd Hazmi and Hashim, Hasnur Zaman (2014) A rare case of acute psychosis as an isolated manifestation of extrapontine myelinolysis. British Journal of Medicine and Medical Research, 4 (18). pp. 3554-3560. ISSN 2231-0614 http://www.sciencedomain.org/abstract.php?iid=480&id=12&aid=4294 10.9734/BJMMR/2014/9615
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description Aims and Background: Central pontine myelinolysis (CPM) and extrapontine myelinolysis (EPM) are recognized as osmotic demyelination syndrome (ODS). ODS is pathologically characterized by non-inflammatory demyelination of several brain structures with sparing of axons. This condition is usually associated with overzealous correction of hyponatraemia. Acute psychosis as the sole clinical manifestation is extremely rare. Presentation of Case: Hence, we report an interesting case of a middle-aged man who was diagnosed with EPM, following rapid correction of hyponatraemia and subsequently developed acute psychosis. He made a good recovery with supportive treatment alone. Discussion and Conclusion: The possibility of psychosis as a manifestation of ODS, particularly in patients with recent correction of hyponatraemia. The rate of correction of plasma sodium level is the key point for preventing ODS and its complications.
format Article
author Wan Sulaiman, Wan Aliaa
Hoo, Fan Kee
Basri, Hamidon
Hasan, Shariful
Mohd Sazlly Lim, Sazlyna
Foo, Yoke Loong
Ching, Siew Mooi
Vasudevan, Ramachandran
Mohamed, Mohd Hazmi
Hashim, Hasnur Zaman
spellingShingle Wan Sulaiman, Wan Aliaa
Hoo, Fan Kee
Basri, Hamidon
Hasan, Shariful
Mohd Sazlly Lim, Sazlyna
Foo, Yoke Loong
Ching, Siew Mooi
Vasudevan, Ramachandran
Mohamed, Mohd Hazmi
Hashim, Hasnur Zaman
A rare case of acute psychosis as an isolated manifestation of extrapontine myelinolysis
author_facet Wan Sulaiman, Wan Aliaa
Hoo, Fan Kee
Basri, Hamidon
Hasan, Shariful
Mohd Sazlly Lim, Sazlyna
Foo, Yoke Loong
Ching, Siew Mooi
Vasudevan, Ramachandran
Mohamed, Mohd Hazmi
Hashim, Hasnur Zaman
author_sort Wan Sulaiman, Wan Aliaa
title A rare case of acute psychosis as an isolated manifestation of extrapontine myelinolysis
title_short A rare case of acute psychosis as an isolated manifestation of extrapontine myelinolysis
title_full A rare case of acute psychosis as an isolated manifestation of extrapontine myelinolysis
title_fullStr A rare case of acute psychosis as an isolated manifestation of extrapontine myelinolysis
title_full_unstemmed A rare case of acute psychosis as an isolated manifestation of extrapontine myelinolysis
title_sort rare case of acute psychosis as an isolated manifestation of extrapontine myelinolysis
publisher Sciencedomain International
publishDate 2014
url http://psasir.upm.edu.my/id/eprint/36246/1/A%20rare%20case%20of%20acute%20psychosis%20as%20an%20isolated%20manifestation%20of%20extrapontine%20myelinolysis.pdf
http://psasir.upm.edu.my/id/eprint/36246/
http://www.sciencedomain.org/abstract.php?iid=480&id=12&aid=4294
_version_ 1643831691267014656
score 13.211869

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