Vitiligo: symptoms, pathogenesis and treatment
Vitiligo is an acquired cutaneous disorder of pigmentation, with an incidence of 0.5% to 2% worldwide. There are three major hypotheses for the pathogenesis of vitiligo that are not exclusive of each other: biochemical/cytotoxic, neural and autoimmune. Recent data provide stron...
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2014
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my.upm.eprints.359932016-02-12T07:22:14Z http://psasir.upm.edu.my/id/eprint/35993/ Vitiligo: symptoms, pathogenesis and treatment Ghafourian, E. Ghafourian, Sobhan Sadeghifard, Nourkhoda Mohebi, Reza Shokoohini, Y. Nezamoleslami, S. Hamat, Rukman Awang Vitiligo is an acquired cutaneous disorder of pigmentation, with an incidence of 0.5% to 2% worldwide. There are three major hypotheses for the pathogenesis of vitiligo that are not exclusive of each other: biochemical/cytotoxic, neural and autoimmune. Recent data provide strong evidence supporting an autoimmune pathogenesis of vitiligo. As vitiligo can have a major effect on quality of life, treatment can be considered and should preferably begin early when then disease is active. Current treatment modalities are directed towards stopping progression of the disease and achieving repigmentation. Therapies include corticosteroids, topical immunomodulators, photo(chemo)therapy, surgery, combination therapies and depigmentation of normally pigmented skin. It seems that traditional Chinese medicine could be more effective than the current treatment for vitligo. Sage Publications 2014-10 Article PeerReviewed Ghafourian, E. and Ghafourian, Sobhan and Sadeghifard, Nourkhoda and Mohebi, Reza and Shokoohini, Y. and Nezamoleslami, S. and Hamat, Rukman Awang (2014) Vitiligo: symptoms, pathogenesis and treatment. International Journal of Immunopathology and Pharmacology, 27 (4). pp. 485-489. ISSN 0394-6320 http://iji.sagepub.com/content/27/4/485.abstract 10.1177/039463201402700403 |
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Vitiligo is an acquired cutaneous disorder of pigmentation, with an incidence of 0.5% to 2% worldwide. There are three major hypotheses for the pathogenesis of vitiligo that are not exclusive of each other: biochemical/cytotoxic, neural and autoimmune. Recent data provide strong evidence supporting an autoimmune pathogenesis of vitiligo. As vitiligo can have a major effect on quality of life, treatment can be considered and should preferably begin early when then disease is active. Current treatment modalities are directed towards stopping progression of the disease and achieving repigmentation. Therapies include corticosteroids, topical immunomodulators, photo(chemo)therapy, surgery, combination therapies and depigmentation of normally pigmented skin. It seems that traditional Chinese medicine could be more effective than the current treatment for vitligo. |
| format |
Article |
| author |
Ghafourian, E. Ghafourian, Sobhan Sadeghifard, Nourkhoda Mohebi, Reza Shokoohini, Y. Nezamoleslami, S. Hamat, Rukman Awang |
| spellingShingle |
Ghafourian, E. Ghafourian, Sobhan Sadeghifard, Nourkhoda Mohebi, Reza Shokoohini, Y. Nezamoleslami, S. Hamat, Rukman Awang Vitiligo: symptoms, pathogenesis and treatment |
| author_facet |
Ghafourian, E. Ghafourian, Sobhan Sadeghifard, Nourkhoda Mohebi, Reza Shokoohini, Y. Nezamoleslami, S. Hamat, Rukman Awang |
| author_sort |
Ghafourian, E. |
| title |
Vitiligo: symptoms, pathogenesis and treatment |
| title_short |
Vitiligo: symptoms, pathogenesis and treatment |
| title_full |
Vitiligo: symptoms, pathogenesis and treatment |
| title_fullStr |
Vitiligo: symptoms, pathogenesis and treatment |
| title_full_unstemmed |
Vitiligo: symptoms, pathogenesis and treatment |
| title_sort |
vitiligo: symptoms, pathogenesis and treatment |
| publisher |
Sage Publications |
| publishDate |
2014 |
| url |
http://psasir.upm.edu.my/id/eprint/35993/ http://iji.sagepub.com/content/27/4/485.abstract |
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1643831617320386560 |
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13.211869 |