Cover Image

Newcastle disease virus activated human peripheral blood mononuclear cells and their use in cancer therapy.

This invention provides a method for immune activation of human peripheral blood mononuclear cells (PBMC) by treatment with immunogens derived from New Castle Disease virus (NDV). The invention describes a method of activation of PBMC by NDV, the activated PBMCs produced by the inventive method as w...

Full description

Saved in:
Bibliographic Details
Main Authors: Mohammed Alitheen, Noorjahan Banu, Lam, Han Yuen, Yusoff, Khatijah, Abd Aziz, Suraini, Keong, Yeap Swee
Format: Patent
Published: 2010
Online Access:http://psasir.upm.edu.my/id/eprint/32058/
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.upm.eprints.32058
record_format eprints
spelling my.upm.eprints.320582014-09-03T06:30:29Z http://psasir.upm.edu.my/id/eprint/32058/ Newcastle disease virus activated human peripheral blood mononuclear cells and their use in cancer therapy. Mohammed Alitheen, Noorjahan Banu Lam, Han Yuen Yusoff, Khatijah Abd Aziz, Suraini Keong, Yeap Swee This invention provides a method for immune activation of human peripheral blood mononuclear cells (PBMC) by treatment with immunogens derived from New Castle Disease virus (NDV). The invention describes a method of activation of PBMC by NDV, the activated PBMCs produced by the inventive method as well as pharmaceutical compositions and vaccines comprising the same. Further embodiments of the invention relate to the use of NDV derived immunogens and the inventive activated PBMCs in immunetheraphy of proliferative diseases - such as cancer. The invention finally provides a method for killing target cells, preferably cancer cells, by co-culturing the target cells together with the inventive activated PBMCs. 2010-11-30 Patent NonPeerReviewed Noorjahan Banu Mohammed Alitheen. (2010) Newcastle disease virus activated human peripheral blood mononuclear cells and their use in cancer therapy. PI2010700088.
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
description This invention provides a method for immune activation of human peripheral blood mononuclear cells (PBMC) by treatment with immunogens derived from New Castle Disease virus (NDV). The invention describes a method of activation of PBMC by NDV, the activated PBMCs produced by the inventive method as well as pharmaceutical compositions and vaccines comprising the same. Further embodiments of the invention relate to the use of NDV derived immunogens and the inventive activated PBMCs in immunetheraphy of proliferative diseases - such as cancer. The invention finally provides a method for killing target cells, preferably cancer cells, by co-culturing the target cells together with the inventive activated PBMCs.
format Patent
author Mohammed Alitheen, Noorjahan Banu
Lam, Han Yuen
Yusoff, Khatijah
Abd Aziz, Suraini
Keong, Yeap Swee
spellingShingle Mohammed Alitheen, Noorjahan Banu
Lam, Han Yuen
Yusoff, Khatijah
Abd Aziz, Suraini
Keong, Yeap Swee
Newcastle disease virus activated human peripheral blood mononuclear cells and their use in cancer therapy.
author_facet Mohammed Alitheen, Noorjahan Banu
Lam, Han Yuen
Yusoff, Khatijah
Abd Aziz, Suraini
Keong, Yeap Swee
author_sort Mohammed Alitheen, Noorjahan Banu
title Newcastle disease virus activated human peripheral blood mononuclear cells and their use in cancer therapy.
title_short Newcastle disease virus activated human peripheral blood mononuclear cells and their use in cancer therapy.
title_full Newcastle disease virus activated human peripheral blood mononuclear cells and their use in cancer therapy.
title_fullStr Newcastle disease virus activated human peripheral blood mononuclear cells and their use in cancer therapy.
title_full_unstemmed Newcastle disease virus activated human peripheral blood mononuclear cells and their use in cancer therapy.
title_sort newcastle disease virus activated human peripheral blood mononuclear cells and their use in cancer therapy.
publishDate 2010
url http://psasir.upm.edu.my/id/eprint/32058/
_version_ 1643830497366769664
score 13.211869

Similar Items