Effects of S-adenosyl-L-homocysteine and trichostatin A on developmental competence, epigenetic modification, and gene expression in cloned cattle embryos

With regards to low efficiency of the somatic cell nuclear transfer (SCNT)procedure the hypothesis that epigenetic marks of somatic donor cells are responsible for this inefficiency is proposed. Epigenetic marks such as DNA methylation and histone acetylation are two major participants in nuclear...

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Bibliographic Details
Main Author: Jafari, Shahram
Format: Thesis
Language:English
Published: 2012
Subjects:
Online Access:http://psasir.upm.edu.my/id/eprint/31916/7/FP%202012%209%20pdf.pdf
http://psasir.upm.edu.my/id/eprint/31916/
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