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Effects of ß-Glucan on growth performance and immunomodulation in weaned piglets

Seventy-four weaned piglets were used in a 6-week experiment to determine the effects of ß-Glucan on growth performance and immunomodulation of weaned piglets. Piglets were randomly chosen and divided into control and treatment groups. Body weight gain and feed consumption were recorded at weeks 2,...

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Main Authors: Lee, Jin Wee, Ooi, Peck Toung
Format: Conference or Workshop Item
Language:English
Published: 2010
Online Access:http://psasir.upm.edu.my/id/eprint/30971/1/Proceedings-39.pdf
http://psasir.upm.edu.my/id/eprint/30971/
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spelling my.upm.eprints.309712015-01-21T06:52:03Z http://psasir.upm.edu.my/id/eprint/30971/ Effects of ß-Glucan on growth performance and immunomodulation in weaned piglets Lee, Jin Wee Ooi, Peck Toung Seventy-four weaned piglets were used in a 6-week experiment to determine the effects of ß-Glucan on growth performance and immunomodulation of weaned piglets. Piglets were randomly chosen and divided into control and treatment groups. Body weight gain and feed consumption were recorded at weeks 2, 3 and 6. The immunomodulatory effects of ß-Glucan were determined by gross examination of lung lesions during post mortem. Weaned piglets from the treatment group had overall greater growth performance compared to the control group. This was also evident from the overall higher body weight and percentage of body weight gain as well as a lower feed conversion ratio. The fecal coliform count also implied that fecal coliform count in the treatment group was lower than the control group. Piglets treated with ß-Glucan were observed to have positive immunomodulatory effects on piglets. This was shown by an overall lower lung lesion score in the treatment group. The post mortem revealed 2 piglets with fibrinous pneumonia (APP) and 1 pig with severe atrophic rhinitis (Grade 5). In conclusion, treatment with ß-Glucan may lessen inflammatory response towards Gram negative bacteria via the inhibition of inflammatory cytokines and promote the production of anti-inflammatory cytokines. Further studies are needed to determine the efficacy of ß-Glucan in reducing total coliform count and its effect on immunomodulation. 2010-01-05 Conference or Workshop Item PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/30971/1/Proceedings-39.pdf Lee, Jin Wee and Ooi, Peck Toung (2010) Effects of ß-Glucan on growth performance and immunomodulation in weaned piglets. In: 5th Seminar on Veterinary Sciences, 5-8 Jan. 2010, Serdang, Selangor. .
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description Seventy-four weaned piglets were used in a 6-week experiment to determine the effects of ß-Glucan on growth performance and immunomodulation of weaned piglets. Piglets were randomly chosen and divided into control and treatment groups. Body weight gain and feed consumption were recorded at weeks 2, 3 and 6. The immunomodulatory effects of ß-Glucan were determined by gross examination of lung lesions during post mortem. Weaned piglets from the treatment group had overall greater growth performance compared to the control group. This was also evident from the overall higher body weight and percentage of body weight gain as well as a lower feed conversion ratio. The fecal coliform count also implied that fecal coliform count in the treatment group was lower than the control group. Piglets treated with ß-Glucan were observed to have positive immunomodulatory effects on piglets. This was shown by an overall lower lung lesion score in the treatment group. The post mortem revealed 2 piglets with fibrinous pneumonia (APP) and 1 pig with severe atrophic rhinitis (Grade 5). In conclusion, treatment with ß-Glucan may lessen inflammatory response towards Gram negative bacteria via the inhibition of inflammatory cytokines and promote the production of anti-inflammatory cytokines. Further studies are needed to determine the efficacy of ß-Glucan in reducing total coliform count and its effect on immunomodulation.
format Conference or Workshop Item
author Lee, Jin Wee
Ooi, Peck Toung
spellingShingle Lee, Jin Wee
Ooi, Peck Toung
Effects of ß-Glucan on growth performance and immunomodulation in weaned piglets
author_facet Lee, Jin Wee
Ooi, Peck Toung
author_sort Lee, Jin Wee
title Effects of ß-Glucan on growth performance and immunomodulation in weaned piglets
title_short Effects of ß-Glucan on growth performance and immunomodulation in weaned piglets
title_full Effects of ß-Glucan on growth performance and immunomodulation in weaned piglets
title_fullStr Effects of ß-Glucan on growth performance and immunomodulation in weaned piglets
title_full_unstemmed Effects of ß-Glucan on growth performance and immunomodulation in weaned piglets
title_sort effects of ß-glucan on growth performance and immunomodulation in weaned piglets
publishDate 2010
url http://psasir.upm.edu.my/id/eprint/30971/1/Proceedings-39.pdf
http://psasir.upm.edu.my/id/eprint/30971/
_version_ 1643830219015979008
score 13.211869

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