Synthesis of new cytotoxic aminoanthraquinone derivatives via nucleophilic substitution reactions
Aminoanthraquinones were successfully synthesized via two reaction steps. 1,4-Dihydroxyanthraquinone (1) was first subjected to methylation, reduction and acylation to give an excellent yield of anthracene-1,4-dione (3), 1,4-dimethoxyanthracene-9,10-dione (5) and 9,10-dioxo-9,10-dihydroanthracene-1,...
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Main Authors: | Mohd Nor, Siti Mariam, Md. Sukari, Mohd. Aspollah, Syed Abd. Azziz, Saripah Salbiah, Wong, Chee Fah, Alimon, Hasimah, Juhan, Siti Fadilah |
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Format: | Article |
Language: | English English |
Published: |
Multidisciplinary Digital Publishing Institute
2013
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Online Access: | http://psasir.upm.edu.my/id/eprint/30099/1/Synthesis%20of%20new%20cytotoxic%20aminoanthraquinone%20derivatives%20via%20nucleophilic%20substitution%20reactions.pdf http://psasir.upm.edu.my/id/eprint/30099/ http://www.mdpi.com/1420-3049/18/7 |
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