Staff View: Lipase-catalyzed amino sugar derivative in tri-solvent mixture

Lipase-catalyzed amino sugar derivative in tri-solvent mixture

In this work, a new type of amino sugar derivative tagged as amino sugar similar to N-acetyl-glucosamine, commonly used in medical field as medicine to treat osteoarthritis has been synthesized. This amino sugar derivative produced from glucose and propylamine with the aid of immobilized Candida ant...

Full description

Saved in:

Bibliographic Details
Main Authors:	Abdul Rahman, Mohd Basyaruddin, Krishnan, Devandran, Haron, Md. Jelas, Tejo, Bimo Ario, Abd. Malek, Emilia, Salleh, Abu Bakar, Basri, Mahiran
Format:	Article
Language:	English English
Published:	Chemic Publishing Company 2013
Online Access:	http://psasir.upm.edu.my/id/eprint/30025/1/Lipase.pdf http://psasir.upm.edu.my/id/eprint/30025/ http://www.asianjournalofchemistry.co.in/User/SearchArticle.aspx?Volume=25&Issue=6&Article=&Criteria=
Tags:	Add Tag No Tags, Be the first to tag this record!

id	my.upm.eprints.30025
record_format	eprints
spelling	my.upm.eprints.300252015-09-15T01:52:40Z http://psasir.upm.edu.my/id/eprint/30025/ Lipase-catalyzed amino sugar derivative in tri-solvent mixture Abdul Rahman, Mohd Basyaruddin Krishnan, Devandran Haron, Md. Jelas Tejo, Bimo Ario Abd. Malek, Emilia Salleh, Abu Bakar Basri, Mahiran In this work, a new type of amino sugar derivative tagged as amino sugar similar to N-acetyl-glucosamine, commonly used in medical field as medicine to treat osteoarthritis has been synthesized. This amino sugar derivative produced from glucose and propylamine with the aid of immobilized Candida antarctica (Novozyme 435) lipase, as catalyst. Mixtures of solvent influence the high solubility of sugar and thus increasing the yield. Optimization studies such as time, molar ratio, temperature and enzyme quantity conducted for optimization. Optimized condition yields 73.37 % amino sugar was obtained upon 2 h of reaction, 1:5 molar ratio of substrates, 40 ºC temperature and 17 % enzyme mass. Chemic Publishing Company 2013 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/30025/1/Lipase.pdf Abdul Rahman, Mohd Basyaruddin and Krishnan, Devandran and Haron, Md. Jelas and Tejo, Bimo Ario and Abd. Malek, Emilia and Salleh, Abu Bakar and Basri, Mahiran (2013) Lipase-catalyzed amino sugar derivative in tri-solvent mixture. Asian Journal of Chemistry, 25 (6). pp. 3014-3018. ISSN 0970-7077 http://www.asianjournalofchemistry.co.in/User/SearchArticle.aspx?Volume=25&Issue=6&Article=&Criteria= 10.14233/ajchem.2013.13492 English
institution	Universiti Putra Malaysia
building	UPM Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Putra Malaysia
content_source	UPM Institutional Repository
url_provider	http://psasir.upm.edu.my/
language	English English
description	In this work, a new type of amino sugar derivative tagged as amino sugar similar to N-acetyl-glucosamine, commonly used in medical field as medicine to treat osteoarthritis has been synthesized. This amino sugar derivative produced from glucose and propylamine with the aid of immobilized Candida antarctica (Novozyme 435) lipase, as catalyst. Mixtures of solvent influence the high solubility of sugar and thus increasing the yield. Optimization studies such as time, molar ratio, temperature and enzyme quantity conducted for optimization. Optimized condition yields 73.37 % amino sugar was obtained upon 2 h of reaction, 1:5 molar ratio of substrates, 40 ºC temperature and 17 % enzyme mass.
format	Article
author	Abdul Rahman, Mohd Basyaruddin Krishnan, Devandran Haron, Md. Jelas Tejo, Bimo Ario Abd. Malek, Emilia Salleh, Abu Bakar Basri, Mahiran
spellingShingle	Abdul Rahman, Mohd Basyaruddin Krishnan, Devandran Haron, Md. Jelas Tejo, Bimo Ario Abd. Malek, Emilia Salleh, Abu Bakar Basri, Mahiran Lipase-catalyzed amino sugar derivative in tri-solvent mixture
author_facet	Abdul Rahman, Mohd Basyaruddin Krishnan, Devandran Haron, Md. Jelas Tejo, Bimo Ario Abd. Malek, Emilia Salleh, Abu Bakar Basri, Mahiran
author_sort	Abdul Rahman, Mohd Basyaruddin
title	Lipase-catalyzed amino sugar derivative in tri-solvent mixture
title_short	Lipase-catalyzed amino sugar derivative in tri-solvent mixture
title_full	Lipase-catalyzed amino sugar derivative in tri-solvent mixture
title_fullStr	Lipase-catalyzed amino sugar derivative in tri-solvent mixture
title_full_unstemmed	Lipase-catalyzed amino sugar derivative in tri-solvent mixture
title_sort	lipase-catalyzed amino sugar derivative in tri-solvent mixture
publisher	Chemic Publishing Company
publishDate	2013
url	http://psasir.upm.edu.my/id/eprint/30025/1/Lipase.pdf http://psasir.upm.edu.my/id/eprint/30025/ http://www.asianjournalofchemistry.co.in/User/SearchArticle.aspx?Volume=25&Issue=6&Article=&Criteria=
_version_	1643829934454472704
score	13.211869

Lipase-catalyzed amino sugar derivative in tri-solvent mixture

Similar Items