Reproductive characteristic of the female laboratory rat

The laboratory rat is widely used in research studies as a model of mammalian health and disease. This review provides the basic facts about female rat reproduction and highlights the reproductive characteristics which make the rat a preferred animal model for research on reproduction. Rats have sho...

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Main Authors: Hamid, Huda Yahia, Abu Bakar @ Zakaria, Md Zuki
Format: Article
Language:English
Published: Academic Journals 2013
Online Access:http://psasir.upm.edu.my/id/eprint/29857/1/29857.pdf
http://psasir.upm.edu.my/id/eprint/29857/
http://www.academicjournals.org/journal/AJB/article-abstract/073343722578
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spelling my.upm.eprints.298572017-11-10T02:39:30Z http://psasir.upm.edu.my/id/eprint/29857/ Reproductive characteristic of the female laboratory rat Hamid, Huda Yahia Abu Bakar @ Zakaria, Md Zuki The laboratory rat is widely used in research studies as a model of mammalian health and disease. This review provides the basic facts about female rat reproduction and highlights the reproductive characteristics which make the rat a preferred animal model for research on reproduction. Rats have short estrous cycle, lasting four to five days. The estrous cycle consists of four stages known as proestrus, estrus, metestrus and diestrus. Phases of the estrous cycle can be detected by observing behavioral changes or examining vaginal cytology. Detection of sperm in vaginal smear is an excellent predictor of pregnancy in rats. Implantation is initiated on day 5 and completed by day 7 of pregnancy. Gestation takes 21 to 23 days from copulation to parturition. Short estrous cycle and gestation period make the rat an ideal animal model for research on reproduction. Academic Journals 2013-05 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/29857/1/29857.pdf Hamid, Huda Yahia and Abu Bakar @ Zakaria, Md Zuki (2013) Reproductive characteristic of the female laboratory rat. African Journal of Biotechnology, 12 (19). art. no. 073343722578 . pp. 2510-2514. ISSN 1684–5315 http://www.academicjournals.org/journal/AJB/article-abstract/073343722578 10.5897/AJB12.2046
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description The laboratory rat is widely used in research studies as a model of mammalian health and disease. This review provides the basic facts about female rat reproduction and highlights the reproductive characteristics which make the rat a preferred animal model for research on reproduction. Rats have short estrous cycle, lasting four to five days. The estrous cycle consists of four stages known as proestrus, estrus, metestrus and diestrus. Phases of the estrous cycle can be detected by observing behavioral changes or examining vaginal cytology. Detection of sperm in vaginal smear is an excellent predictor of pregnancy in rats. Implantation is initiated on day 5 and completed by day 7 of pregnancy. Gestation takes 21 to 23 days from copulation to parturition. Short estrous cycle and gestation period make the rat an ideal animal model for research on reproduction.
format Article
author Hamid, Huda Yahia
Abu Bakar @ Zakaria, Md Zuki
spellingShingle Hamid, Huda Yahia
Abu Bakar @ Zakaria, Md Zuki
Reproductive characteristic of the female laboratory rat
author_facet Hamid, Huda Yahia
Abu Bakar @ Zakaria, Md Zuki
author_sort Hamid, Huda Yahia
title Reproductive characteristic of the female laboratory rat
title_short Reproductive characteristic of the female laboratory rat
title_full Reproductive characteristic of the female laboratory rat
title_fullStr Reproductive characteristic of the female laboratory rat
title_full_unstemmed Reproductive characteristic of the female laboratory rat
title_sort reproductive characteristic of the female laboratory rat
publisher Academic Journals
publishDate 2013
url http://psasir.upm.edu.my/id/eprint/29857/1/29857.pdf
http://psasir.upm.edu.my/id/eprint/29857/
http://www.academicjournals.org/journal/AJB/article-abstract/073343722578
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score 13.211869