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Potential of 3’-fluoro-3’ deoxythymidine as a cellular proliferation marker in PET oncology examination

Development of the positron emission tomography (PET) diagnostic radiopharmaceutical (18F) fluoro-2-deoxy-D-glucose (18F-FDG) subsequently facilitated the discovery and clinical evaluation of several new tracers as imaging markers for cancer. While 18F-FDG is a widely employed marker for enhanced in...

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Main Authors: Hassan, Hishar, Price, Roger, Ahmad Saad, Fathinul Fikri, Lau, Eddie Wing Fai, Carpinelli, Assunta, Nordin, Abdul Jalil
Format: Article
Language:English
Published: Universiti Putra Malaysia Press 2016
Online Access:http://psasir.upm.edu.my/id/eprint/29519/1/03%20JST-0544-2015%20Rev1-%20Hishar%20Hassanr-Review%20Paper.pdf
http://psasir.upm.edu.my/id/eprint/29519/
http://www.pertanika.upm.edu.my/Pertanika%20PAPERS/JST%20Vol.%2024%20(1)%20Jan.%202016/03%20JST-0544-2015%20Rev1-%20Hishar%20Hassanr-Review%20Paper.pdf
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spelling my.upm.eprints.295192017-11-15T08:12:47Z http://psasir.upm.edu.my/id/eprint/29519/ Potential of 3’-fluoro-3’ deoxythymidine as a cellular proliferation marker in PET oncology examination Hassan, Hishar Price, Roger Ahmad Saad, Fathinul Fikri Lau, Eddie Wing Fai Carpinelli, Assunta Nordin, Abdul Jalil Development of the positron emission tomography (PET) diagnostic radiopharmaceutical (18F) fluoro-2-deoxy-D-glucose (18F-FDG) subsequently facilitated the discovery and clinical evaluation of several new tracers as imaging markers for cancer. While 18F-FDG is a widely employed marker for enhanced intracellular glycolysis and metabolic function, one of the newer tracers, (18F)-3’-fluoro-3’ deoxythymidine (18F-FLT), has been developed as a biomarker for cell proliferation. In this review, the potential of 18F-FLT as a biomarker for cancer imaging is discussed. Universiti Putra Malaysia Press 2016 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/29519/1/03%20JST-0544-2015%20Rev1-%20Hishar%20Hassanr-Review%20Paper.pdf Hassan, Hishar and Price, Roger and Ahmad Saad, Fathinul Fikri and Lau, Eddie Wing Fai and Carpinelli, Assunta and Nordin, Abdul Jalil (2016) Potential of 3’-fluoro-3’ deoxythymidine as a cellular proliferation marker in PET oncology examination. Pertanika Journal of Science & Technology, 24 (1). pp. 41-52. ISSN 0128-7680; ESSN: 2231-8526 http://www.pertanika.upm.edu.my/Pertanika%20PAPERS/JST%20Vol.%2024%20(1)%20Jan.%202016/03%20JST-0544-2015%20Rev1-%20Hishar%20Hassanr-Review%20Paper.pdf
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description Development of the positron emission tomography (PET) diagnostic radiopharmaceutical (18F) fluoro-2-deoxy-D-glucose (18F-FDG) subsequently facilitated the discovery and clinical evaluation of several new tracers as imaging markers for cancer. While 18F-FDG is a widely employed marker for enhanced intracellular glycolysis and metabolic function, one of the newer tracers, (18F)-3’-fluoro-3’ deoxythymidine (18F-FLT), has been developed as a biomarker for cell proliferation. In this review, the potential of 18F-FLT as a biomarker for cancer imaging is discussed.
format Article
author Hassan, Hishar
Price, Roger
Ahmad Saad, Fathinul Fikri
Lau, Eddie Wing Fai
Carpinelli, Assunta
Nordin, Abdul Jalil
spellingShingle Hassan, Hishar
Price, Roger
Ahmad Saad, Fathinul Fikri
Lau, Eddie Wing Fai
Carpinelli, Assunta
Nordin, Abdul Jalil
Potential of 3’-fluoro-3’ deoxythymidine as a cellular proliferation marker in PET oncology examination
author_facet Hassan, Hishar
Price, Roger
Ahmad Saad, Fathinul Fikri
Lau, Eddie Wing Fai
Carpinelli, Assunta
Nordin, Abdul Jalil
author_sort Hassan, Hishar
title Potential of 3’-fluoro-3’ deoxythymidine as a cellular proliferation marker in PET oncology examination
title_short Potential of 3’-fluoro-3’ deoxythymidine as a cellular proliferation marker in PET oncology examination
title_full Potential of 3’-fluoro-3’ deoxythymidine as a cellular proliferation marker in PET oncology examination
title_fullStr Potential of 3’-fluoro-3’ deoxythymidine as a cellular proliferation marker in PET oncology examination
title_full_unstemmed Potential of 3’-fluoro-3’ deoxythymidine as a cellular proliferation marker in PET oncology examination
title_sort potential of 3’-fluoro-3’ deoxythymidine as a cellular proliferation marker in pet oncology examination
publisher Universiti Putra Malaysia Press
publishDate 2016
url http://psasir.upm.edu.my/id/eprint/29519/1/03%20JST-0544-2015%20Rev1-%20Hishar%20Hassanr-Review%20Paper.pdf
http://psasir.upm.edu.my/id/eprint/29519/
http://www.pertanika.upm.edu.my/Pertanika%20PAPERS/JST%20Vol.%2024%20(1)%20Jan.%202016/03%20JST-0544-2015%20Rev1-%20Hishar%20Hassanr-Review%20Paper.pdf
_version_ 1643829784388567040
score 13.223943

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