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Phytochemical analysis of Andrographis paniculata and Orthosiphon stamineus leaf extracts for their antibacterial and antioxidant potential.

Leaves of Andrographis paniculata and Orthosiphon stamineus were extracted with water, ethanol, methanol and chloroform to assess their potential as antibacterial and antioxidant agents. High performance liquid chromatography analysis showed that the methanolic extracts of A. paniculata and O. stami...

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Main Authors: Malahubban, M., Alimon, Abdul Razak, Sazili, Awis Qurni, Fakurazi, Sharida, Ab Aziz, Zakry Fitri
Format: Article
Language:English
English
Published: Malaysian Society of Parasitology and Tropical Medicine 2013
Online Access:http://psasir.upm.edu.my/id/eprint/29422/1/Phytochemical%20analysis%20of%20Andrographis%20paniculata%20and%20Orthosiphon%20stamineus%20leaf%20extracts%20for%20their%20antibacterial%20and%20antioxidant%20potential.pdf
http://psasir.upm.edu.my/id/eprint/29422/
http://www.msptm.org/journal27.html
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spelling my.upm.eprints.294222015-10-08T06:50:39Z http://psasir.upm.edu.my/id/eprint/29422/ Phytochemical analysis of Andrographis paniculata and Orthosiphon stamineus leaf extracts for their antibacterial and antioxidant potential. Malahubban, M. Alimon, Abdul Razak Sazili, Awis Qurni Fakurazi, Sharida Ab Aziz, Zakry Fitri Leaves of Andrographis paniculata and Orthosiphon stamineus were extracted with water, ethanol, methanol and chloroform to assess their potential as antibacterial and antioxidant agents. High performance liquid chromatography analysis showed that the methanolic extracts of A. paniculata and O. stamineus leaves gave the highest amounts of andrographolide and rosmarinic acid, respectively. These leaf extracts exhibited antimicrobial and antioxidant activities and, at the highest concentration tested (200 mg/mL), showed greater inhibitory effects against the Gram positive bacteria Bacillus cereus and Staphylococcus aureus than 10% acetic acid. Andrographis paniculata and O. stamineus methanolic and ethanolic leaf extracts also showed the strongest antioxidant activity as compared with the other extracts tested. The bioactive compounds present in these leaf extracts have the potential to be developed into natural antibacterial and antioxidant agents that may have applications in animal and human health. Malaysian Society of Parasitology and Tropical Medicine 2013 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/29422/1/Phytochemical%20analysis%20of%20Andrographis%20paniculata%20and%20Orthosiphon%20stamineus%20leaf%20extracts%20for%20their%20antibacterial%20and%20antioxidant%20potential.pdf Malahubban, M. and Alimon, Abdul Razak and Sazili, Awis Qurni and Fakurazi, Sharida and Ab Aziz, Zakry Fitri (2013) Phytochemical analysis of Andrographis paniculata and Orthosiphon stamineus leaf extracts for their antibacterial and antioxidant potential. Tropical Biomedicine, 30 (3). pp. 467-480. ISSN 0127-5720 http://www.msptm.org/journal27.html English
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
English
description Leaves of Andrographis paniculata and Orthosiphon stamineus were extracted with water, ethanol, methanol and chloroform to assess their potential as antibacterial and antioxidant agents. High performance liquid chromatography analysis showed that the methanolic extracts of A. paniculata and O. stamineus leaves gave the highest amounts of andrographolide and rosmarinic acid, respectively. These leaf extracts exhibited antimicrobial and antioxidant activities and, at the highest concentration tested (200 mg/mL), showed greater inhibitory effects against the Gram positive bacteria Bacillus cereus and Staphylococcus aureus than 10% acetic acid. Andrographis paniculata and O. stamineus methanolic and ethanolic leaf extracts also showed the strongest antioxidant activity as compared with the other extracts tested. The bioactive compounds present in these leaf extracts have the potential to be developed into natural antibacterial and antioxidant agents that may have applications in animal and human health.
format Article
author Malahubban, M.
Alimon, Abdul Razak
Sazili, Awis Qurni
Fakurazi, Sharida
Ab Aziz, Zakry Fitri
spellingShingle Malahubban, M.
Alimon, Abdul Razak
Sazili, Awis Qurni
Fakurazi, Sharida
Ab Aziz, Zakry Fitri
Phytochemical analysis of Andrographis paniculata and Orthosiphon stamineus leaf extracts for their antibacterial and antioxidant potential.
author_facet Malahubban, M.
Alimon, Abdul Razak
Sazili, Awis Qurni
Fakurazi, Sharida
Ab Aziz, Zakry Fitri
author_sort Malahubban, M.
title Phytochemical analysis of Andrographis paniculata and Orthosiphon stamineus leaf extracts for their antibacterial and antioxidant potential.
title_short Phytochemical analysis of Andrographis paniculata and Orthosiphon stamineus leaf extracts for their antibacterial and antioxidant potential.
title_full Phytochemical analysis of Andrographis paniculata and Orthosiphon stamineus leaf extracts for their antibacterial and antioxidant potential.
title_fullStr Phytochemical analysis of Andrographis paniculata and Orthosiphon stamineus leaf extracts for their antibacterial and antioxidant potential.
title_full_unstemmed Phytochemical analysis of Andrographis paniculata and Orthosiphon stamineus leaf extracts for their antibacterial and antioxidant potential.
title_sort phytochemical analysis of andrographis paniculata and orthosiphon stamineus leaf extracts for their antibacterial and antioxidant potential.
publisher Malaysian Society of Parasitology and Tropical Medicine
publishDate 2013
url http://psasir.upm.edu.my/id/eprint/29422/1/Phytochemical%20analysis%20of%20Andrographis%20paniculata%20and%20Orthosiphon%20stamineus%20leaf%20extracts%20for%20their%20antibacterial%20and%20antioxidant%20potential.pdf
http://psasir.upm.edu.my/id/eprint/29422/
http://www.msptm.org/journal27.html
_version_ 1643829756518465536
score 13.211869

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