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Theobroma cacao: review of the extraction, isolation, and bioassay of its potential anti-cancer compounds

Plants have been a good source of therapeutic agents for thousands of years; an impressive number of modern drugs used for treating human diseases are derived from natural sources. The Theobroma cacao tree, or cocoa, has recently garnered increasing attention and become the subject of research due t...

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Main Authors: Baharum, Zainal, Md. Akim, Abdah, Yap, Taufiq Yun Hin, Abd Hamid @ Abdul Razak, Roslida, Kasran, Rosmin
Format: Article
Language:English
Published: Penerbit Universiti Sains Malaysia 2016
Online Access:http://psasir.upm.edu.my/id/eprint/29166/1/Theobroma%20cacao%20review%20of%20the%20extraction%2C%20isolation%2C%20and%20bioassay%20of%20its%20potential%20anti-cancer%20compounds.pdf
http://psasir.upm.edu.my/id/eprint/29166/
http://www.tlsr.usm.my/current.html
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spelling my.upm.eprints.291662016-06-20T06:49:47Z http://psasir.upm.edu.my/id/eprint/29166/ Theobroma cacao: review of the extraction, isolation, and bioassay of its potential anti-cancer compounds Baharum, Zainal Md. Akim, Abdah Yap, Taufiq Yun Hin Abd Hamid @ Abdul Razak, Roslida Kasran, Rosmin Plants have been a good source of therapeutic agents for thousands of years; an impressive number of modern drugs used for treating human diseases are derived from natural sources. The Theobroma cacao tree, or cocoa, has recently garnered increasing attention and become the subject of research due to its antioxidant properties, which are related to potential anti-cancer effects. In the past few years, identifying and developing active compounds or extracts from the cocoa bean that might exert anti-cancer effects have become an important area of health- and biomedicine-related research. This review provides an updated overview of T. cacao in terms of its potential anti-cancer compounds and their extraction, in vitro bioassay, purification, and identification. This article also discusses the advantages and disadvantages of the techniques described and reviews the processes for future perspectives of analytical methods from the viewpoint of anti-cancer compound discovery. Penerbit Universiti Sains Malaysia 2016 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/29166/1/Theobroma%20cacao%20review%20of%20the%20extraction%2C%20isolation%2C%20and%20bioassay%20of%20its%20potential%20anti-cancer%20compounds.pdf Baharum, Zainal and Md. Akim, Abdah and Yap, Taufiq Yun Hin and Abd Hamid @ Abdul Razak, Roslida and Kasran, Rosmin (2016) Theobroma cacao: review of the extraction, isolation, and bioassay of its potential anti-cancer compounds. Tropical Life Sciences Research, 27 (1). pp. 21-42. ISSN 1985-3718; ESSN: 2180-4249 http://www.tlsr.usm.my/current.html
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description Plants have been a good source of therapeutic agents for thousands of years; an impressive number of modern drugs used for treating human diseases are derived from natural sources. The Theobroma cacao tree, or cocoa, has recently garnered increasing attention and become the subject of research due to its antioxidant properties, which are related to potential anti-cancer effects. In the past few years, identifying and developing active compounds or extracts from the cocoa bean that might exert anti-cancer effects have become an important area of health- and biomedicine-related research. This review provides an updated overview of T. cacao in terms of its potential anti-cancer compounds and their extraction, in vitro bioassay, purification, and identification. This article also discusses the advantages and disadvantages of the techniques described and reviews the processes for future perspectives of analytical methods from the viewpoint of anti-cancer compound discovery.
format Article
author Baharum, Zainal
Md. Akim, Abdah
Yap, Taufiq Yun Hin
Abd Hamid @ Abdul Razak, Roslida
Kasran, Rosmin
spellingShingle Baharum, Zainal
Md. Akim, Abdah
Yap, Taufiq Yun Hin
Abd Hamid @ Abdul Razak, Roslida
Kasran, Rosmin
Theobroma cacao: review of the extraction, isolation, and bioassay of its potential anti-cancer compounds
author_facet Baharum, Zainal
Md. Akim, Abdah
Yap, Taufiq Yun Hin
Abd Hamid @ Abdul Razak, Roslida
Kasran, Rosmin
author_sort Baharum, Zainal
title Theobroma cacao: review of the extraction, isolation, and bioassay of its potential anti-cancer compounds
title_short Theobroma cacao: review of the extraction, isolation, and bioassay of its potential anti-cancer compounds
title_full Theobroma cacao: review of the extraction, isolation, and bioassay of its potential anti-cancer compounds
title_fullStr Theobroma cacao: review of the extraction, isolation, and bioassay of its potential anti-cancer compounds
title_full_unstemmed Theobroma cacao: review of the extraction, isolation, and bioassay of its potential anti-cancer compounds
title_sort theobroma cacao: review of the extraction, isolation, and bioassay of its potential anti-cancer compounds
publisher Penerbit Universiti Sains Malaysia
publishDate 2016
url http://psasir.upm.edu.my/id/eprint/29166/1/Theobroma%20cacao%20review%20of%20the%20extraction%2C%20isolation%2C%20and%20bioassay%20of%20its%20potential%20anti-cancer%20compounds.pdf
http://psasir.upm.edu.my/id/eprint/29166/
http://www.tlsr.usm.my/current.html
_version_ 1643829679667281920
score 13.211869

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