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The effects of meloxicam on the growth and viability of mouse mammary tumour cell lines EMT6 and 4T1

The in vitro growth of mouse mammary tumour cell lines EMT6 (benign type) and 4T1 (malignant type) were evaluated following treatment with three different doses of meloxicam. The viability and growth of these cells following treatment were determined via cell proliferation and live-dead assays. Cell...

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Main Authors: Cornelius, Cecilia Evelyn, Mohd Noor, Mohd Hezmee
Format: Conference or Workshop Item
Language:English
Published: 2012
Online Access:http://psasir.upm.edu.my/id/eprint/26797/1/PROCEEDING%2022.pdf
http://psasir.upm.edu.my/id/eprint/26797/
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spelling my.upm.eprints.267972016-08-10T08:09:42Z http://psasir.upm.edu.my/id/eprint/26797/ The effects of meloxicam on the growth and viability of mouse mammary tumour cell lines EMT6 and 4T1 Cornelius, Cecilia Evelyn Mohd Noor, Mohd Hezmee The in vitro growth of mouse mammary tumour cell lines EMT6 (benign type) and 4T1 (malignant type) were evaluated following treatment with three different doses of meloxicam. The viability and growth of these cells following treatment were determined via cell proliferation and live-dead assays. Cell proliferation assay for these cells showed the absorbance of treated cells was significantly (p<0.05) higher than the control. The live-dead assay showed that the viability of the treated cells was significantly (p<0.05) lower than the control for EMT6 cells while there was no significant difference for the 4T1 cells, however the viability of the treated cells was lower than the control. This study provides preliminary evidence that meloxicam may inhibit growth and viability of mouse mammary tumour cell lines EMT6 and 4T1. 2012 Conference or Workshop Item PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/26797/1/PROCEEDING%2022.pdf Cornelius, Cecilia Evelyn and Mohd Noor, Mohd Hezmee (2012) The effects of meloxicam on the growth and viability of mouse mammary tumour cell lines EMT6 and 4T1. In: 7th Seminar in Veterinary Sciences, 27 Feb.-2 Mar. 2012, Faculty of Veterinary Medicine, Universiti Putra Malaysia. (p. 80).
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description The in vitro growth of mouse mammary tumour cell lines EMT6 (benign type) and 4T1 (malignant type) were evaluated following treatment with three different doses of meloxicam. The viability and growth of these cells following treatment were determined via cell proliferation and live-dead assays. Cell proliferation assay for these cells showed the absorbance of treated cells was significantly (p<0.05) higher than the control. The live-dead assay showed that the viability of the treated cells was significantly (p<0.05) lower than the control for EMT6 cells while there was no significant difference for the 4T1 cells, however the viability of the treated cells was lower than the control. This study provides preliminary evidence that meloxicam may inhibit growth and viability of mouse mammary tumour cell lines EMT6 and 4T1.
format Conference or Workshop Item
author Cornelius, Cecilia Evelyn
Mohd Noor, Mohd Hezmee
spellingShingle Cornelius, Cecilia Evelyn
Mohd Noor, Mohd Hezmee
The effects of meloxicam on the growth and viability of mouse mammary tumour cell lines EMT6 and 4T1
author_facet Cornelius, Cecilia Evelyn
Mohd Noor, Mohd Hezmee
author_sort Cornelius, Cecilia Evelyn
title The effects of meloxicam on the growth and viability of mouse mammary tumour cell lines EMT6 and 4T1
title_short The effects of meloxicam on the growth and viability of mouse mammary tumour cell lines EMT6 and 4T1
title_full The effects of meloxicam on the growth and viability of mouse mammary tumour cell lines EMT6 and 4T1
title_fullStr The effects of meloxicam on the growth and viability of mouse mammary tumour cell lines EMT6 and 4T1
title_full_unstemmed The effects of meloxicam on the growth and viability of mouse mammary tumour cell lines EMT6 and 4T1
title_sort effects of meloxicam on the growth and viability of mouse mammary tumour cell lines emt6 and 4t1
publishDate 2012
url http://psasir.upm.edu.my/id/eprint/26797/1/PROCEEDING%2022.pdf
http://psasir.upm.edu.my/id/eprint/26797/
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score 13.211869

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