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Immunohistological localisation of Coxiella burnetii in various organs of naturally Q-fever infected goats

The rather uncommonly reported Q-fever disease in Malaysia is currently demonstrating an increasing trend of outbreaks. A total of 197 goat carcasses during the period of July 2007 to December 2009 were submitted to Regional Diagnostic Laboratory (MVK), Bukit Tengah, Penang, for post-mortem examinat...

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Main Authors: Lukman, Norina, Yusoff, Md. Sabri, Goh, Yong Meng, Saad, Mohd Zamri, Awang Besar, Sarenasulastri, Mohd Hanan, Latifah, Jaadil, Jamilah, Mohamed Mustapha, Noordin
Format: Article
Language:English
Published: Universiti Putra Malaysia Press 2011
Online Access:http://psasir.upm.edu.my/id/eprint/25429/1/21%20Pg%20167-174.pdf
http://psasir.upm.edu.my/id/eprint/25429/
http://www.pertanika.upm.edu.my/Pertanika%20PAPERS/JTAS%20Vol.%2034%20(1)%20Feb.%202011/21%20Pg%20167-174.pdf
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spelling my.upm.eprints.254292016-11-22T02:12:57Z http://psasir.upm.edu.my/id/eprint/25429/ Immunohistological localisation of Coxiella burnetii in various organs of naturally Q-fever infected goats Lukman, Norina Yusoff, Md. Sabri Goh, Yong Meng Saad, Mohd Zamri Awang Besar, Sarenasulastri Mohd Hanan, Latifah Jaadil, Jamilah Mohamed Mustapha, Noordin The rather uncommonly reported Q-fever disease in Malaysia is currently demonstrating an increasing trend of outbreaks. A total of 197 goat carcasses during the period of July 2007 to December 2009 were submitted to Regional Diagnostic Laboratory (MVK), Bukit Tengah, Penang, for post-mortem examination. Morphological diagnosis of necrotic placentitis, interstitial pneumonia, hepatitis and nephritis were observed in majority of the cases. Likewise, Giemsa stained sections of selected tissues revealed C.burnetii trophoblast. Acute cases yielded lesions conforming to doughnut granuloma, while those of the chronic form exhibited chronic inflammation. In an attempt to further confirm the presence of the organism, these selected tissues were subjected to immunohistochemical confirmation. Out of the total suspected cases, 152 (77.2%) were confirmed as positive of Q-fever based on their IHC. Thus, this study demonstrated pertinent lesions of acute and chronic forms of Q-fever which might be beneficial to laboratories without IHC facilities. Universiti Putra Malaysia Press 2011-02 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/25429/1/21%20Pg%20167-174.pdf Lukman, Norina and Yusoff, Md. Sabri and Goh, Yong Meng and Saad, Mohd Zamri and Awang Besar, Sarenasulastri and Mohd Hanan, Latifah and Jaadil, Jamilah and Mohamed Mustapha, Noordin (2011) Immunohistological localisation of Coxiella burnetii in various organs of naturally Q-fever infected goats. Pertanika Journal of Tropical Agricultural Science, 34 (1). pp. 167-173. ISSN 1511-3701; ESSN: 2231-8542 http://www.pertanika.upm.edu.my/Pertanika%20PAPERS/JTAS%20Vol.%2034%20(1)%20Feb.%202011/21%20Pg%20167-174.pdf
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description The rather uncommonly reported Q-fever disease in Malaysia is currently demonstrating an increasing trend of outbreaks. A total of 197 goat carcasses during the period of July 2007 to December 2009 were submitted to Regional Diagnostic Laboratory (MVK), Bukit Tengah, Penang, for post-mortem examination. Morphological diagnosis of necrotic placentitis, interstitial pneumonia, hepatitis and nephritis were observed in majority of the cases. Likewise, Giemsa stained sections of selected tissues revealed C.burnetii trophoblast. Acute cases yielded lesions conforming to doughnut granuloma, while those of the chronic form exhibited chronic inflammation. In an attempt to further confirm the presence of the organism, these selected tissues were subjected to immunohistochemical confirmation. Out of the total suspected cases, 152 (77.2%) were confirmed as positive of Q-fever based on their IHC. Thus, this study demonstrated pertinent lesions of acute and chronic forms of Q-fever which might be beneficial to laboratories without IHC facilities.
format Article
author Lukman, Norina
Yusoff, Md. Sabri
Goh, Yong Meng
Saad, Mohd Zamri
Awang Besar, Sarenasulastri
Mohd Hanan, Latifah
Jaadil, Jamilah
Mohamed Mustapha, Noordin
spellingShingle Lukman, Norina
Yusoff, Md. Sabri
Goh, Yong Meng
Saad, Mohd Zamri
Awang Besar, Sarenasulastri
Mohd Hanan, Latifah
Jaadil, Jamilah
Mohamed Mustapha, Noordin
Immunohistological localisation of Coxiella burnetii in various organs of naturally Q-fever infected goats
author_facet Lukman, Norina
Yusoff, Md. Sabri
Goh, Yong Meng
Saad, Mohd Zamri
Awang Besar, Sarenasulastri
Mohd Hanan, Latifah
Jaadil, Jamilah
Mohamed Mustapha, Noordin
author_sort Lukman, Norina
title Immunohistological localisation of Coxiella burnetii in various organs of naturally Q-fever infected goats
title_short Immunohistological localisation of Coxiella burnetii in various organs of naturally Q-fever infected goats
title_full Immunohistological localisation of Coxiella burnetii in various organs of naturally Q-fever infected goats
title_fullStr Immunohistological localisation of Coxiella burnetii in various organs of naturally Q-fever infected goats
title_full_unstemmed Immunohistological localisation of Coxiella burnetii in various organs of naturally Q-fever infected goats
title_sort immunohistological localisation of coxiella burnetii in various organs of naturally q-fever infected goats
publisher Universiti Putra Malaysia Press
publishDate 2011
url http://psasir.upm.edu.my/id/eprint/25429/1/21%20Pg%20167-174.pdf
http://psasir.upm.edu.my/id/eprint/25429/
http://www.pertanika.upm.edu.my/Pertanika%20PAPERS/JTAS%20Vol.%2034%20(1)%20Feb.%202011/21%20Pg%20167-174.pdf
_version_ 1643828657715675136
score 13.211869

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