Cover Image

Parametric estimation of the immunes proportion based on BCH model and exponential distribution using left censored data.

In population based cancer clinical trials, a proportion of patients will never experience the interested event and considered as "cured" or "immunes". The majority of recent cancer studies focus on the estimation of immune proportion. In this study we investigated the estimation...

Full description

Saved in:
Bibliographic Details
Main Authors: I. Aljawadi, Bader Ahmad, Abu Bakar, Mohd Rizam, Ibrahim, Noor Akma, Midi, Habshah
Format: Article
Language:English
English
Published: Asian Network for Scientific Information 2011
Online Access:http://psasir.upm.edu.my/id/eprint/25131/1/Parametric%20estimation%20of%20the%20immunes%20proportion%20based%20on%20BCH%20model%20and%20exponential%20distribution%20using%20left%20censored%20data.pdf
http://psasir.upm.edu.my/id/eprint/25131/
http://www.ansinet.com/
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.upm.eprints.25131
record_format eprints
spelling my.upm.eprints.251312015-09-23T03:22:31Z http://psasir.upm.edu.my/id/eprint/25131/ Parametric estimation of the immunes proportion based on BCH model and exponential distribution using left censored data. I. Aljawadi, Bader Ahmad Abu Bakar, Mohd Rizam Ibrahim, Noor Akma Midi, Habshah In population based cancer clinical trials, a proportion of patients will never experience the interested event and considered as "cured" or "immunes". The majority of recent cancer studies focus on the estimation of immune proportion. In this study we investigated the estimation of proportion of patients curd of cancer in case of left censored data based on the Bounded Cumulative Hazard (BCH) model proposed by Chen in 1999. The analysis provided the Maximum Likelihood Estimation (MLE) of the parameters within the framework of the Expectation Maximization (EM) algorithm where the numerical solutions of the estimation equations of the cure rate parameter could be employed. Asian Network for Scientific Information 2011 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/25131/1/Parametric%20estimation%20of%20the%20immunes%20proportion%20based%20on%20BCH%20model%20and%20exponential%20distribution%20using%20left%20censored%20data.pdf I. Aljawadi, Bader Ahmad and Abu Bakar, Mohd Rizam and Ibrahim, Noor Akma and Midi, Habshah (2011) Parametric estimation of the immunes proportion based on BCH model and exponential distribution using left censored data. Journal of Applied Sciences, 11 (15). pp. 2861-2865. ISSN 1812-5654 http://www.ansinet.com/ 10.3923/jas.2011.2861.2865 English
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
English
description In population based cancer clinical trials, a proportion of patients will never experience the interested event and considered as "cured" or "immunes". The majority of recent cancer studies focus on the estimation of immune proportion. In this study we investigated the estimation of proportion of patients curd of cancer in case of left censored data based on the Bounded Cumulative Hazard (BCH) model proposed by Chen in 1999. The analysis provided the Maximum Likelihood Estimation (MLE) of the parameters within the framework of the Expectation Maximization (EM) algorithm where the numerical solutions of the estimation equations of the cure rate parameter could be employed.
format Article
author I. Aljawadi, Bader Ahmad
Abu Bakar, Mohd Rizam
Ibrahim, Noor Akma
Midi, Habshah
spellingShingle I. Aljawadi, Bader Ahmad
Abu Bakar, Mohd Rizam
Ibrahim, Noor Akma
Midi, Habshah
Parametric estimation of the immunes proportion based on BCH model and exponential distribution using left censored data.
author_facet I. Aljawadi, Bader Ahmad
Abu Bakar, Mohd Rizam
Ibrahim, Noor Akma
Midi, Habshah
author_sort I. Aljawadi, Bader Ahmad
title Parametric estimation of the immunes proportion based on BCH model and exponential distribution using left censored data.
title_short Parametric estimation of the immunes proportion based on BCH model and exponential distribution using left censored data.
title_full Parametric estimation of the immunes proportion based on BCH model and exponential distribution using left censored data.
title_fullStr Parametric estimation of the immunes proportion based on BCH model and exponential distribution using left censored data.
title_full_unstemmed Parametric estimation of the immunes proportion based on BCH model and exponential distribution using left censored data.
title_sort parametric estimation of the immunes proportion based on bch model and exponential distribution using left censored data.
publisher Asian Network for Scientific Information
publishDate 2011
url http://psasir.upm.edu.my/id/eprint/25131/1/Parametric%20estimation%20of%20the%20immunes%20proportion%20based%20on%20BCH%20model%20and%20exponential%20distribution%20using%20left%20censored%20data.pdf
http://psasir.upm.edu.my/id/eprint/25131/
http://www.ansinet.com/
_version_ 1643828569333301248
score 13.211869

Similar Items