Possible participation of nitric oxide/cyclic guanosine monophosphate/protein kinase C/ATP-sensitive K + channels pathway in the systemic antinociception of flavokawin B.
The possible mechanisms of action in the antinociceptive activity induced by systemic administration (intraperitoneal, i.p.) of flavokawin B (FKB) were analysed using chemical models of nociception in mice. It was demonstrated that i.p. administration of FKB to the mice at 0.3, 1.0, 3.0 and 10 mg/k...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English English |
| Published: |
Wiley
2011
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| Online Access: | http://psasir.upm.edu.my/id/eprint/24557/1/Possible%20participation%20of%20nitric%20oxide.pdf http://psasir.upm.edu.my/id/eprint/24557/ |
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