Cover Image

In vitro inhibitory potential of selected Malaysian plants against key enzymes involved in hyperglycemia and hypertension.

Introduction: This study was conducted to determine the inhibitory potential of selected Malaysian plants against key enzymes related to type 2 diabetes and hypertension. Methods: The samples investigated were pucuk ubi (Manihot esculenta), pucuk betik (Carica papaya), ulam raja (Cosmos caudatus)...

Full description

Saved in:
Bibliographic Details
Main Authors: Loh, Su Peng, O., Hadira
Format: Article
Language:English
English
Published: Nutrition Society of Malaysia 2011
Online Access:http://psasir.upm.edu.my/id/eprint/24476/1/In%20vitro%20inhibitory%20potential%20of%20selected%20Malaysian%20plants%20against%20key%20enzymes%20involved%20in%20hyperglycemia%20and%20hypertension.pdf
http://psasir.upm.edu.my/id/eprint/24476/
http://www.nutriweb.org.my/publications/mjn0019_2/default.php
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.upm.eprints.24476
record_format eprints
spelling my.upm.eprints.244762015-10-05T01:46:37Z http://psasir.upm.edu.my/id/eprint/24476/ In vitro inhibitory potential of selected Malaysian plants against key enzymes involved in hyperglycemia and hypertension. Loh, Su Peng O., Hadira Introduction: This study was conducted to determine the inhibitory potential of selected Malaysian plants against key enzymes related to type 2 diabetes and hypertension. Methods: The samples investigated were pucuk ubi (Manihot esculenta), pucuk betik (Carica papaya), ulam raja (Cosmos caudatus), pegaga (Centella asiatica) and kacang botol (Psophocarpus tetragonolobus). The inhibitory potential of hexane and dichloromethane extracts against the enzymes were determined by using α-amylase, α-glucosidase and angiotensin I-converting enzyme (ACE) inhibition assay. Results: In α-amylase inhibition assay, the inhibitory potential was highest in pucuk ubi for both hexane (59.22%) and dichloromethane extract (54.15%). Hexane extract of pucuk ubi (95.01%) and dichloromethane extract of kacang botol (38.94%) showed the highest inhibitory potential against α- glucosidase,while in ACE inhibition assay, the inhibitory potential was highest in hexane extract of pegaga (48.45%) and dichloromethane extract of pucuk betik (59.77%). Conclusion: This study suggests a nutraceutical potential of some of these plants for hyperglycemia and hypertension prevention associated with type 2 diabetes. Nutrition Society of Malaysia 2011 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/24476/1/In%20vitro%20inhibitory%20potential%20of%20selected%20Malaysian%20plants%20against%20key%20enzymes%20involved%20in%20hyperglycemia%20and%20hypertension.pdf Loh, Su Peng and O., Hadira (2011) In vitro inhibitory potential of selected Malaysian plants against key enzymes involved in hyperglycemia and hypertension. Malaysian Journal of Nutrition, 17 (1). pp. 77-86. ISSN 1394-035X http://www.nutriweb.org.my/publications/mjn0019_2/default.php English
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
English
description Introduction: This study was conducted to determine the inhibitory potential of selected Malaysian plants against key enzymes related to type 2 diabetes and hypertension. Methods: The samples investigated were pucuk ubi (Manihot esculenta), pucuk betik (Carica papaya), ulam raja (Cosmos caudatus), pegaga (Centella asiatica) and kacang botol (Psophocarpus tetragonolobus). The inhibitory potential of hexane and dichloromethane extracts against the enzymes were determined by using α-amylase, α-glucosidase and angiotensin I-converting enzyme (ACE) inhibition assay. Results: In α-amylase inhibition assay, the inhibitory potential was highest in pucuk ubi for both hexane (59.22%) and dichloromethane extract (54.15%). Hexane extract of pucuk ubi (95.01%) and dichloromethane extract of kacang botol (38.94%) showed the highest inhibitory potential against α- glucosidase,while in ACE inhibition assay, the inhibitory potential was highest in hexane extract of pegaga (48.45%) and dichloromethane extract of pucuk betik (59.77%). Conclusion: This study suggests a nutraceutical potential of some of these plants for hyperglycemia and hypertension prevention associated with type 2 diabetes.
format Article
author Loh, Su Peng
O., Hadira
spellingShingle Loh, Su Peng
O., Hadira
In vitro inhibitory potential of selected Malaysian plants against key enzymes involved in hyperglycemia and hypertension.
author_facet Loh, Su Peng
O., Hadira
author_sort Loh, Su Peng
title In vitro inhibitory potential of selected Malaysian plants against key enzymes involved in hyperglycemia and hypertension.
title_short In vitro inhibitory potential of selected Malaysian plants against key enzymes involved in hyperglycemia and hypertension.
title_full In vitro inhibitory potential of selected Malaysian plants against key enzymes involved in hyperglycemia and hypertension.
title_fullStr In vitro inhibitory potential of selected Malaysian plants against key enzymes involved in hyperglycemia and hypertension.
title_full_unstemmed In vitro inhibitory potential of selected Malaysian plants against key enzymes involved in hyperglycemia and hypertension.
title_sort in vitro inhibitory potential of selected malaysian plants against key enzymes involved in hyperglycemia and hypertension.
publisher Nutrition Society of Malaysia
publishDate 2011
url http://psasir.upm.edu.my/id/eprint/24476/1/In%20vitro%20inhibitory%20potential%20of%20selected%20Malaysian%20plants%20against%20key%20enzymes%20involved%20in%20hyperglycemia%20and%20hypertension.pdf
http://psasir.upm.edu.my/id/eprint/24476/
http://www.nutriweb.org.my/publications/mjn0019_2/default.php
_version_ 1643828371606470656
score 13.211869

Similar Items