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Effect of pre-germination time of brown rice on serum cholesterol levels of hypercholesterolaemic rats.

Background: Brown rice is unpolished rice with immeasurable benefits for human health. Brown rice (BR) and pre-germinated brown rice (PGBR) are known to contain various functional compounds such as gamma-oryzanol, dietary fibre and gamma-aminobutyric acid (GABA). In the present study, the experiment...

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Main Authors: Roohinejad, Shahin, Omidizadeh, Alireza, Mirhosseini, Hamed, Saari, Nazamid, Mustafa, Shuhaimi, Mohd Yusof, Rokiah, Hussin, Anis Shobirin, Abdul Hamid, Azizah, Abd. Manap, Mohd. Yazid
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Language:English
English
Published: Wiley-Blackwell 2010
Online Access:http://psasir.upm.edu.my/id/eprint/24036/1/Effect%20of%20pre-germination%20time%20of%20brown%20rice%20on%20serum%20cholesterol%20levels%20of%20hypercholesterolaemic%20rats..pdf
http://psasir.upm.edu.my/id/eprint/24036/
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spelling my.upm.eprints.240362015-11-02T02:43:54Z http://psasir.upm.edu.my/id/eprint/24036/ Effect of pre-germination time of brown rice on serum cholesterol levels of hypercholesterolaemic rats. Roohinejad, Shahin Omidizadeh, Alireza Mirhosseini, Hamed Saari, Nazamid Mustafa, Shuhaimi Mohd Yusof, Rokiah Hussin, Anis Shobirin Abdul Hamid, Azizah Abd. Manap, Mohd. Yazid Background: Brown rice is unpolished rice with immeasurable benefits for human health. Brown rice (BR) and pre-germinated brown rice (PGBR) are known to contain various functional compounds such as gamma-oryzanol, dietary fibre and gamma-aminobutyric acid (GABA). In the present study, the experimental diets containing BR and PGBR (24, 48 h pre-germination) were used to investigate the influence of pre-germination time of brown rice on blood cholesterol in Sprague-Dawley male rats. Result: Hypercholesterolaemia and elevation of LDL-cholesterol were successfully ameliorated by the experimental diets containing BR and PGBR (24 and 48 h pre-germination). As compared to the control sample, the pre-germination time had a significant (P < 0.05) effect on blood cholesterol of Sprague-Dawley male rats. It was also found that the significantly (P < 0.05) better effect on lipid profile of hypercholesterolaemic rats was observed by prolonging the pre-germination time. As compared to non-germinated brown rice, the germinated brown rice showed the higher cardio-protective effect on hypercholesterolaemic Sprague-Dawley male rats. Conclusion: The present study suggests that the changes of blood cholesterol can be mainly modulated by using the PGBR rather than BR. The prolonging of pre-germination time led to an increase in the bioactive components, thereby providing a more efficient functional diet affecting the high blood cholesterol. This study suggests that PGBR can be used instead of BR and polished rice in the human diet. Wiley-Blackwell 2010-01-30 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/24036/1/Effect%20of%20pre-germination%20time%20of%20brown%20rice%20on%20serum%20cholesterol%20levels%20of%20hypercholesterolaemic%20rats..pdf Roohinejad, Shahin and Omidizadeh, Alireza and Mirhosseini, Hamed and Saari, Nazamid and Mustafa, Shuhaimi and Mohd Yusof, Rokiah and Hussin, Anis Shobirin and Abdul Hamid, Azizah and Abd. Manap, Mohd. Yazid (2010) Effect of pre-germination time of brown rice on serum cholesterol levels of hypercholesterolaemic rats. Journal of the Science of Food and Agriculture, 90 (2). pp. 245-251. ISSN 0022-5142, ESSN:1097-0010 http://www.wiley.com/ 10.1002/jsfa.3803 English
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
English
description Background: Brown rice is unpolished rice with immeasurable benefits for human health. Brown rice (BR) and pre-germinated brown rice (PGBR) are known to contain various functional compounds such as gamma-oryzanol, dietary fibre and gamma-aminobutyric acid (GABA). In the present study, the experimental diets containing BR and PGBR (24, 48 h pre-germination) were used to investigate the influence of pre-germination time of brown rice on blood cholesterol in Sprague-Dawley male rats. Result: Hypercholesterolaemia and elevation of LDL-cholesterol were successfully ameliorated by the experimental diets containing BR and PGBR (24 and 48 h pre-germination). As compared to the control sample, the pre-germination time had a significant (P < 0.05) effect on blood cholesterol of Sprague-Dawley male rats. It was also found that the significantly (P < 0.05) better effect on lipid profile of hypercholesterolaemic rats was observed by prolonging the pre-germination time. As compared to non-germinated brown rice, the germinated brown rice showed the higher cardio-protective effect on hypercholesterolaemic Sprague-Dawley male rats. Conclusion: The present study suggests that the changes of blood cholesterol can be mainly modulated by using the PGBR rather than BR. The prolonging of pre-germination time led to an increase in the bioactive components, thereby providing a more efficient functional diet affecting the high blood cholesterol. This study suggests that PGBR can be used instead of BR and polished rice in the human diet.
format Article
author Roohinejad, Shahin
Omidizadeh, Alireza
Mirhosseini, Hamed
Saari, Nazamid
Mustafa, Shuhaimi
Mohd Yusof, Rokiah
Hussin, Anis Shobirin
Abdul Hamid, Azizah
Abd. Manap, Mohd. Yazid
spellingShingle Roohinejad, Shahin
Omidizadeh, Alireza
Mirhosseini, Hamed
Saari, Nazamid
Mustafa, Shuhaimi
Mohd Yusof, Rokiah
Hussin, Anis Shobirin
Abdul Hamid, Azizah
Abd. Manap, Mohd. Yazid
Effect of pre-germination time of brown rice on serum cholesterol levels of hypercholesterolaemic rats.
author_facet Roohinejad, Shahin
Omidizadeh, Alireza
Mirhosseini, Hamed
Saari, Nazamid
Mustafa, Shuhaimi
Mohd Yusof, Rokiah
Hussin, Anis Shobirin
Abdul Hamid, Azizah
Abd. Manap, Mohd. Yazid
author_sort Roohinejad, Shahin
title Effect of pre-germination time of brown rice on serum cholesterol levels of hypercholesterolaemic rats.
title_short Effect of pre-germination time of brown rice on serum cholesterol levels of hypercholesterolaemic rats.
title_full Effect of pre-germination time of brown rice on serum cholesterol levels of hypercholesterolaemic rats.
title_fullStr Effect of pre-germination time of brown rice on serum cholesterol levels of hypercholesterolaemic rats.
title_full_unstemmed Effect of pre-germination time of brown rice on serum cholesterol levels of hypercholesterolaemic rats.
title_sort effect of pre-germination time of brown rice on serum cholesterol levels of hypercholesterolaemic rats.
publisher Wiley-Blackwell
publishDate 2010
url http://psasir.upm.edu.my/id/eprint/24036/1/Effect%20of%20pre-germination%20time%20of%20brown%20rice%20on%20serum%20cholesterol%20levels%20of%20hypercholesterolaemic%20rats..pdf
http://psasir.upm.edu.my/id/eprint/24036/
http://www.wiley.com/
_version_ 1643828240408641536
score 13.211869

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