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A potential tocopherol acetate loaded palm oil esters-in-water nanoemulsions for nanocosmeceuticals

Background:Cosmeceuticals are cosmetic-pharmaceutical hybrids intended to enhance health and beauty of the skin. Nanocosmeceuticals use nano-sized system for the delivery of active ingredients to the targeted cells for better penetration. In this work, nanoemulsion from palm oil esters was develop...

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Main Authors: Teo, Brian Sheng Xian, Basri, Mahiran, Zakaria, Mohd Rezuwan Shah, Salleh, Abu Bakar, Raja Abdul Rahman, Raja Noor Zaliha, Abdul Rahman, Mohd Basyaruddin
Format: Article
Language:English
Published: BioMed Central 2010
Online Access:http://psasir.upm.edu.my/id/eprint/22294/1/22294.pdf
http://psasir.upm.edu.my/id/eprint/22294/
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spelling my.upm.eprints.222942016-09-26T07:53:45Z http://psasir.upm.edu.my/id/eprint/22294/ A potential tocopherol acetate loaded palm oil esters-in-water nanoemulsions for nanocosmeceuticals Teo, Brian Sheng Xian Basri, Mahiran Zakaria, Mohd Rezuwan Shah Salleh, Abu Bakar Raja Abdul Rahman, Raja Noor Zaliha Abdul Rahman, Mohd Basyaruddin Background:Cosmeceuticals are cosmetic-pharmaceutical hybrids intended to enhance health and beauty of the skin. Nanocosmeceuticals use nano-sized system for the delivery of active ingredients to the targeted cells for better penetration. In this work, nanoemulsion from palm oil esters was developed as a delivery system to produce nanocosmeceuticals. The stability of the resulting formulation was tested using various methods. In addition, the effect of components i.e. Vitamin E and Pluronic F-68 on the formulation was also studied. Results: Both vitamin E and Pluronic F-68 were found to co-emulsify and co-stabilized the formulations. The best formulation was found to be the one having the composition of 10% Palm Oil Esters (POEs), 10% vitamin E, 24% Tween 80, 2.4% Pluronic F-68 and 53.6% deionised water. Those compositions are considered to be the best as a nanocosmeceutical product due to the small particle size (94.21 nm), low occurrence of Ostwald ripening and stable at different storing temperatures (5, 25 and 45°C) for four weeks. Conclusions:Palm oil esters-in-water nanoemulsions loaded with vitamin E was successfully formulated and has the potential for the use as nanocosmeceuticals. BioMed Central 2010 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/22294/1/22294.pdf Teo, Brian Sheng Xian and Basri, Mahiran and Zakaria, Mohd Rezuwan Shah and Salleh, Abu Bakar and Raja Abdul Rahman, Raja Noor Zaliha and Abdul Rahman, Mohd Basyaruddin (2010) A potential tocopherol acetate loaded palm oil esters-in-water nanoemulsions for nanocosmeceuticals. Journal of Nanobiotechnology, 8. art. no. 4. pp. 1-11. ISSN 1477-3155 10.1186/1477-3155-8-4
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description Background:Cosmeceuticals are cosmetic-pharmaceutical hybrids intended to enhance health and beauty of the skin. Nanocosmeceuticals use nano-sized system for the delivery of active ingredients to the targeted cells for better penetration. In this work, nanoemulsion from palm oil esters was developed as a delivery system to produce nanocosmeceuticals. The stability of the resulting formulation was tested using various methods. In addition, the effect of components i.e. Vitamin E and Pluronic F-68 on the formulation was also studied. Results: Both vitamin E and Pluronic F-68 were found to co-emulsify and co-stabilized the formulations. The best formulation was found to be the one having the composition of 10% Palm Oil Esters (POEs), 10% vitamin E, 24% Tween 80, 2.4% Pluronic F-68 and 53.6% deionised water. Those compositions are considered to be the best as a nanocosmeceutical product due to the small particle size (94.21 nm), low occurrence of Ostwald ripening and stable at different storing temperatures (5, 25 and 45°C) for four weeks. Conclusions:Palm oil esters-in-water nanoemulsions loaded with vitamin E was successfully formulated and has the potential for the use as nanocosmeceuticals.
format Article
author Teo, Brian Sheng Xian
Basri, Mahiran
Zakaria, Mohd Rezuwan Shah
Salleh, Abu Bakar
Raja Abdul Rahman, Raja Noor Zaliha
Abdul Rahman, Mohd Basyaruddin
spellingShingle Teo, Brian Sheng Xian
Basri, Mahiran
Zakaria, Mohd Rezuwan Shah
Salleh, Abu Bakar
Raja Abdul Rahman, Raja Noor Zaliha
Abdul Rahman, Mohd Basyaruddin
A potential tocopherol acetate loaded palm oil esters-in-water nanoemulsions for nanocosmeceuticals
author_facet Teo, Brian Sheng Xian
Basri, Mahiran
Zakaria, Mohd Rezuwan Shah
Salleh, Abu Bakar
Raja Abdul Rahman, Raja Noor Zaliha
Abdul Rahman, Mohd Basyaruddin
author_sort Teo, Brian Sheng Xian
title A potential tocopherol acetate loaded palm oil esters-in-water nanoemulsions for nanocosmeceuticals
title_short A potential tocopherol acetate loaded palm oil esters-in-water nanoemulsions for nanocosmeceuticals
title_full A potential tocopherol acetate loaded palm oil esters-in-water nanoemulsions for nanocosmeceuticals
title_fullStr A potential tocopherol acetate loaded palm oil esters-in-water nanoemulsions for nanocosmeceuticals
title_full_unstemmed A potential tocopherol acetate loaded palm oil esters-in-water nanoemulsions for nanocosmeceuticals
title_sort potential tocopherol acetate loaded palm oil esters-in-water nanoemulsions for nanocosmeceuticals
publisher BioMed Central
publishDate 2010
url http://psasir.upm.edu.my/id/eprint/22294/1/22294.pdf
http://psasir.upm.edu.my/id/eprint/22294/
_version_ 1643827786161324032
score 13.211869

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