The role of antenatal vitamin e supplementation in the prevention of neonatal jaundice.
Objective: To determine the effect of maternal antenatal vitamin E supplementation on neonatal jaundice. Methods: A randomized double blind controlled trial assessing the role of vitamin E in the prevention of preeclampsia was conducted in a tertiary hospital over two years. From 12-16 weeks...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English English |
| Published: |
IOS Press
2010
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| Online Access: | http://psasir.upm.edu.my/id/eprint/17313/1/The%20role%20of%20antenatal%20vitamin%20e%20supplementation%20in%20the%20prevention%20of%20neonatal%20jaundice.pdf http://psasir.upm.edu.my/id/eprint/17313/ http://www.iospress.nl |
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| Summary: | Objective:
To determine the effect of maternal antenatal vitamin E supplementation on neonatal jaundice.
Methods:
A randomized double blind controlled trial assessing the role of vitamin E in the prevention of preeclampsia was conducted in a tertiary hospital over two years. From 12-16 weeks gestation until delivery, primigravida mothers with singleton pregnancies received either 100 mg daily vitamin E in the form of tocotrienol rich fraction, or placebo. The newborns were assessed for jaundice.
Results:
Among 262 infants, 136 were in the vitamin E group and 126 in the placebo group. The incidence of neonatal jaundice was similar: 38% (54/136) in the vitamin E group and 36% (45/126) in the placebo group (p= 0.10). Nevertheless, the vitamin E group had a tendency for lower peak serum bilirubin, although not significantly so.
Conclusion:
Maternal antenatal vitamin E supplementation had no effect on the incidence of neonatal jaundice. |
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