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Modelling of chromatin morphologies in breast cancer cells undergoing apoptosis using generalized Cauchy field.

Chromatin morphologies in human breast cancer cells treated with an anti-cancer agent are analyzed at their early stage of programmed cell death or apoptosis. The gray-level images of nuclear chromatin are modelled as random fields. We used two-dimensional isotropic generalized Cauchy field to chara...

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Main Authors: Muniandy, Sithi V., Stanslas, Johnson
Format: Article
Language:English
English
Published: Elsevier 2008
Online Access:http://psasir.upm.edu.my/id/eprint/15672/1/Modelling%20of%20chromatin%20morphologies%20in%20breast%20cancer%20cells%20undergoing%20apoptosis%20using%20generalized%20Cauchy%20field.pdf
http://psasir.upm.edu.my/id/eprint/15672/
http://www.elsevier.com
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spelling my.upm.eprints.156722015-10-23T06:27:55Z http://psasir.upm.edu.my/id/eprint/15672/ Modelling of chromatin morphologies in breast cancer cells undergoing apoptosis using generalized Cauchy field. Muniandy, Sithi V. Stanslas, Johnson Chromatin morphologies in human breast cancer cells treated with an anti-cancer agent are analyzed at their early stage of programmed cell death or apoptosis. The gray-level images of nuclear chromatin are modelled as random fields. We used two-dimensional isotropic generalized Cauchy field to characterize local self-similarity and global long-range dependence behaviors in the image spatial data. Generalized Cauchy field allows the description of fractal behavior inferred from fractal dimension and the long-range dependence inferred from correlation exponent to be carried out independently. We demonstrated the usefulness of locally self-similar random fields with long-range dependence for modelling chromatin condensation. Elsevier 2008-10 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/15672/1/Modelling%20of%20chromatin%20morphologies%20in%20breast%20cancer%20cells%20undergoing%20apoptosis%20using%20generalized%20Cauchy%20field.pdf Muniandy, Sithi V. and Stanslas, Johnson (2008) Modelling of chromatin morphologies in breast cancer cells undergoing apoptosis using generalized Cauchy field. Computerized Medical Imaging and Graphics , 32 (7). pp. 631-637. ISSN 0895-6111; ESSN:1879-0771 http://www.elsevier.com 10.1016/j.compmedimag.2008.07.003 English
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
English
description Chromatin morphologies in human breast cancer cells treated with an anti-cancer agent are analyzed at their early stage of programmed cell death or apoptosis. The gray-level images of nuclear chromatin are modelled as random fields. We used two-dimensional isotropic generalized Cauchy field to characterize local self-similarity and global long-range dependence behaviors in the image spatial data. Generalized Cauchy field allows the description of fractal behavior inferred from fractal dimension and the long-range dependence inferred from correlation exponent to be carried out independently. We demonstrated the usefulness of locally self-similar random fields with long-range dependence for modelling chromatin condensation.
format Article
author Muniandy, Sithi V.
Stanslas, Johnson
spellingShingle Muniandy, Sithi V.
Stanslas, Johnson
Modelling of chromatin morphologies in breast cancer cells undergoing apoptosis using generalized Cauchy field.
author_facet Muniandy, Sithi V.
Stanslas, Johnson
author_sort Muniandy, Sithi V.
title Modelling of chromatin morphologies in breast cancer cells undergoing apoptosis using generalized Cauchy field.
title_short Modelling of chromatin morphologies in breast cancer cells undergoing apoptosis using generalized Cauchy field.
title_full Modelling of chromatin morphologies in breast cancer cells undergoing apoptosis using generalized Cauchy field.
title_fullStr Modelling of chromatin morphologies in breast cancer cells undergoing apoptosis using generalized Cauchy field.
title_full_unstemmed Modelling of chromatin morphologies in breast cancer cells undergoing apoptosis using generalized Cauchy field.
title_sort modelling of chromatin morphologies in breast cancer cells undergoing apoptosis using generalized cauchy field.
publisher Elsevier
publishDate 2008
url http://psasir.upm.edu.my/id/eprint/15672/1/Modelling%20of%20chromatin%20morphologies%20in%20breast%20cancer%20cells%20undergoing%20apoptosis%20using%20generalized%20Cauchy%20field.pdf
http://psasir.upm.edu.my/id/eprint/15672/
http://www.elsevier.com
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score 13.211869

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