Metabolic control in type 2 diabetes correlates weakly with patient adherence to oral hypoglycaemic treatment.

Introduction: Patient adherence to treatment is viewed as essential to good metabolic control in diabetes. Our primary objective was to determine if self-reported patient adherence correlated strongly with metabolic control. Our secondary objective was to determine the natural grouping of factors...

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Bibliographic Details
Main Authors: Loke, Seng Cheong, Jong, Michelle
Format: Article
Language:English
English
Published: Academy of Medicine, Singapore 2008
Online Access:http://psasir.upm.edu.my/id/eprint/15617/1/Metabolic%20control%20in%20type%202%20diabetes%20correlates%20weakly%20with%20patient%20adherence%20to%20oral%20hypoglycaemic%20treatment.pdf
http://psasir.upm.edu.my/id/eprint/15617/
http://www.annals.edu.sg
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Summary:Introduction: Patient adherence to treatment is viewed as essential to good metabolic control in diabetes. Our primary objective was to determine if self-reported patient adherence correlated strongly with metabolic control. Our secondary objective was to determine the natural grouping of factors which influence adherence. Materials and Methods: Data were collected using a questionnaire set with 5-point Likert scales. Primary analysis was done using Spearman's correlation coefficient between self-reported composite adherence scores and HbA1c. Secondary analysis was done using exploratory factor analysis. Results: The primary analysis suggests that patient adherence to the treatment regime is weakly correlated to metabolic control. Calculated Spearman's rho was 0.197, with a two-tailed P value of 0.027. The secondary analysis demonstrates the natural clustering of factors that influence patient adherence to treatment. A 6-factor solution was found to account for most of the variance in the data. We also found that feelings of frustration, anxiety, and depression were associated with a lack of knowledge about diabetes treatment. In addition, belief in traditional medicine correlated strongly with ethnicity. Conclusion: A good treatment regime for type 2 diabetes mellitus influences metabolic outcome far more than patient adherence.