Cover Image

Intestinal microsporidiosis: a new entity in Malaysia?

Objective: Intestinal microsporidia is an emerging human disease caused by microsporidia. A study was conducted to determine the prevalence of microsporidia in patients with gastro-intestinal symptoms and to examine the clinical manifestations associated with intestinal microsporidiosis. Methods:...

Full description

Saved in:
Bibliographic Details
Main Authors: Awang Hamat, Rukman, Osman, Malina, M. I., Noorhayati, Mohammad, Marlyn, Abdullah, Wan Omar, Abd. Majid, Roslaini, Unyah, Ngah Zasmy, Moktar, Norhayati
Format: Article
Language:English
Published: Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2008
Online Access:http://psasir.upm.edu.my/id/eprint/15281/1/Intestinal%20microsporidiosis.pdf
http://psasir.upm.edu.my/id/eprint/15281/
http://www.medic.upm.edu.my/dokumen/FKUSK1_MJMHS_2008V04N2_OP01.pdf
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.upm.eprints.15281
record_format eprints
spelling my.upm.eprints.152812015-10-07T07:35:34Z http://psasir.upm.edu.my/id/eprint/15281/ Intestinal microsporidiosis: a new entity in Malaysia? Awang Hamat, Rukman Osman, Malina M. I., Noorhayati Mohammad, Marlyn Abdullah, Wan Omar Abd. Majid, Roslaini Unyah, Ngah Zasmy Moktar, Norhayati Objective: Intestinal microsporidia is an emerging human disease caused by microsporidia. A study was conducted to determine the prevalence of microsporidia in patients with gastro-intestinal symptoms and to examine the clinical manifestations associated with intestinal microsporidiosis. Methods: A descriptive cross-sectional study using a well-structured questionnaire; a review of medical records was also undertaken. Positive stool samples were defined as presence of one or more pinkish-violet ovoid structures with a belt-like stripe under high power field (100x) using modified gram-chromotrope stain (MGC). Results: A total of 353 faecal specimens of patients was examined and 100 patients were found to have positive stool samples for microsporidia. The overall prevalence of microsporidia was 28.3%. Acute and chronic diarrhoea were seen in 49.0% and 36.0% patients, respectively. The commonest clinical presentations were diarrhoea (85.0%) with 83.0 % of patients having loose or watery stools, vomiting (75.0%), foul-smelling stools (60.0%), nausea (59.0%) and cramping abdominal pain (39.0%). The least common symptoms were fever (15.0%), mucous in stool (5.0%) and blood in stool (4.0%). Conclusion: This study concludes that the prevalence of microsporidia is still high (28.3%) and the majority of patients (93.0%) are symptomatic; the most common gastro-intestinal symptom is diarrhoea with loose or watery stools. Hence, it is recommended that a stool screening for microsporidia be done in selected patients presented with gastrointestinal symptoms. Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2008-06 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/15281/1/Intestinal%20microsporidiosis.pdf Awang Hamat, Rukman and Osman, Malina and M. I., Noorhayati and Mohammad, Marlyn and Abdullah, Wan Omar and Abd. Majid, Roslaini and Unyah, Ngah Zasmy and Moktar, Norhayati (2008) Intestinal microsporidiosis: a new entity in Malaysia? Malaysian Journal of Medicine and Health Sciences, 4 (2). pp. 11-24. ISSN 1675-8544 http://www.medic.upm.edu.my/dokumen/FKUSK1_MJMHS_2008V04N2_OP01.pdf
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description Objective: Intestinal microsporidia is an emerging human disease caused by microsporidia. A study was conducted to determine the prevalence of microsporidia in patients with gastro-intestinal symptoms and to examine the clinical manifestations associated with intestinal microsporidiosis. Methods: A descriptive cross-sectional study using a well-structured questionnaire; a review of medical records was also undertaken. Positive stool samples were defined as presence of one or more pinkish-violet ovoid structures with a belt-like stripe under high power field (100x) using modified gram-chromotrope stain (MGC). Results: A total of 353 faecal specimens of patients was examined and 100 patients were found to have positive stool samples for microsporidia. The overall prevalence of microsporidia was 28.3%. Acute and chronic diarrhoea were seen in 49.0% and 36.0% patients, respectively. The commonest clinical presentations were diarrhoea (85.0%) with 83.0 % of patients having loose or watery stools, vomiting (75.0%), foul-smelling stools (60.0%), nausea (59.0%) and cramping abdominal pain (39.0%). The least common symptoms were fever (15.0%), mucous in stool (5.0%) and blood in stool (4.0%). Conclusion: This study concludes that the prevalence of microsporidia is still high (28.3%) and the majority of patients (93.0%) are symptomatic; the most common gastro-intestinal symptom is diarrhoea with loose or watery stools. Hence, it is recommended that a stool screening for microsporidia be done in selected patients presented with gastrointestinal symptoms.
format Article
author Awang Hamat, Rukman
Osman, Malina
M. I., Noorhayati
Mohammad, Marlyn
Abdullah, Wan Omar
Abd. Majid, Roslaini
Unyah, Ngah Zasmy
Moktar, Norhayati
spellingShingle Awang Hamat, Rukman
Osman, Malina
M. I., Noorhayati
Mohammad, Marlyn
Abdullah, Wan Omar
Abd. Majid, Roslaini
Unyah, Ngah Zasmy
Moktar, Norhayati
Intestinal microsporidiosis: a new entity in Malaysia?
author_facet Awang Hamat, Rukman
Osman, Malina
M. I., Noorhayati
Mohammad, Marlyn
Abdullah, Wan Omar
Abd. Majid, Roslaini
Unyah, Ngah Zasmy
Moktar, Norhayati
author_sort Awang Hamat, Rukman
title Intestinal microsporidiosis: a new entity in Malaysia?
title_short Intestinal microsporidiosis: a new entity in Malaysia?
title_full Intestinal microsporidiosis: a new entity in Malaysia?
title_fullStr Intestinal microsporidiosis: a new entity in Malaysia?
title_full_unstemmed Intestinal microsporidiosis: a new entity in Malaysia?
title_sort intestinal microsporidiosis: a new entity in malaysia?
publisher Faculty of Medicine and Health Sciences, Universiti Putra Malaysia
publishDate 2008
url http://psasir.upm.edu.my/id/eprint/15281/1/Intestinal%20microsporidiosis.pdf
http://psasir.upm.edu.my/id/eprint/15281/
http://www.medic.upm.edu.my/dokumen/FKUSK1_MJMHS_2008V04N2_OP01.pdf
_version_ 1643825887623249920
score 13.211869

Similar Items