Effect of modification of the physicochemical properties of ICAM-1-derived peptides on internalization and intracellular distribution in the human leukemic cell line HL-60
The objective of this work is to test the hypothesis that increasing the hydrophilicity of DOX−peptide conjugates may modify their entry mechanisms into HL-60 cells from passive diffusion to receptor-mediated uptake. To test this hypothesis, the entry mechanisms and the intracellular disposition of...
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| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
American Chemical Society
2009
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| Online Access: | http://psasir.upm.edu.my/id/eprint/14272/1/Effect%20of%20modification%20of%20the%20physicochemical%20properties%20of%20ICAM.pdf http://psasir.upm.edu.my/id/eprint/14272/ |
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