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Antitumour Promoting Activity And Mode Of Action Of Methanolic Extracts Of Selected Malaysian Seaweeds And Oil Palm Fronds

Dietary and non dietary biophenols may potentially be chemoprotective against various cancers. This research aims to investigate the cancer preventive and tumoricidal properties of selected Malaysian seaweeds and oil palm leaves as a source of phenolic compounds. Initially, the anti-proliferatio...

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Main Author: Namvar, Farideh
Format: Thesis
Language:English
English
Published: 2009
Online Access:http://psasir.upm.edu.my/id/eprint/12061/1/IB_2009_18_A.pdf
http://psasir.upm.edu.my/id/eprint/12061/
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spelling my.upm.eprints.120612013-05-27T07:50:57Z http://psasir.upm.edu.my/id/eprint/12061/ Antitumour Promoting Activity And Mode Of Action Of Methanolic Extracts Of Selected Malaysian Seaweeds And Oil Palm Fronds Namvar, Farideh Dietary and non dietary biophenols may potentially be chemoprotective against various cancers. This research aims to investigate the cancer preventive and tumoricidal properties of selected Malaysian seaweeds and oil palm leaves as a source of phenolic compounds. Initially, the anti-proliferation activities of, red (Eucheuma cottonii), green (Caulerpa lentillifera) and brown (Sargassum polycystum) seaweeds methanolic extract, against five important human cancer cell lines MCF-7, (human breast carcinoma cell line, estrogen positive) MDA-MB-231, (human breast carcinoma cell line, estrogen negative) HeLa, (human cervical adenocarcinoma cell line) HepG2, (human hepatocellular carcinoma cell line) HT-29, (human colon carcinoma) and normal Vero (African green monkey kidney cell line) were assessed. The MTT assays indicated that the 3 seaweeds extracts were cytotoxic against all these cancer cell lines in a dose-dependent manner,with Eucheuma cottonii having the greatest inhibition activity. 2009-10 Thesis NonPeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/12061/1/IB_2009_18_A.pdf Namvar, Farideh (2009) Antitumour Promoting Activity And Mode Of Action Of Methanolic Extracts Of Selected Malaysian Seaweeds And Oil Palm Fronds. PhD thesis, Universiti Putra Malaysia. English
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
English
description Dietary and non dietary biophenols may potentially be chemoprotective against various cancers. This research aims to investigate the cancer preventive and tumoricidal properties of selected Malaysian seaweeds and oil palm leaves as a source of phenolic compounds. Initially, the anti-proliferation activities of, red (Eucheuma cottonii), green (Caulerpa lentillifera) and brown (Sargassum polycystum) seaweeds methanolic extract, against five important human cancer cell lines MCF-7, (human breast carcinoma cell line, estrogen positive) MDA-MB-231, (human breast carcinoma cell line, estrogen negative) HeLa, (human cervical adenocarcinoma cell line) HepG2, (human hepatocellular carcinoma cell line) HT-29, (human colon carcinoma) and normal Vero (African green monkey kidney cell line) were assessed. The MTT assays indicated that the 3 seaweeds extracts were cytotoxic against all these cancer cell lines in a dose-dependent manner,with Eucheuma cottonii having the greatest inhibition activity.
format Thesis
author Namvar, Farideh
spellingShingle Namvar, Farideh
Antitumour Promoting Activity And Mode Of Action Of Methanolic Extracts Of Selected Malaysian Seaweeds And Oil Palm Fronds
author_facet Namvar, Farideh
author_sort Namvar, Farideh
title Antitumour Promoting Activity And Mode Of Action Of Methanolic Extracts Of Selected Malaysian Seaweeds And Oil Palm Fronds
title_short Antitumour Promoting Activity And Mode Of Action Of Methanolic Extracts Of Selected Malaysian Seaweeds And Oil Palm Fronds
title_full Antitumour Promoting Activity And Mode Of Action Of Methanolic Extracts Of Selected Malaysian Seaweeds And Oil Palm Fronds
title_fullStr Antitumour Promoting Activity And Mode Of Action Of Methanolic Extracts Of Selected Malaysian Seaweeds And Oil Palm Fronds
title_full_unstemmed Antitumour Promoting Activity And Mode Of Action Of Methanolic Extracts Of Selected Malaysian Seaweeds And Oil Palm Fronds
title_sort antitumour promoting activity and mode of action of methanolic extracts of selected malaysian seaweeds and oil palm fronds
publishDate 2009
url http://psasir.upm.edu.my/id/eprint/12061/1/IB_2009_18_A.pdf
http://psasir.upm.edu.my/id/eprint/12061/
_version_ 1643824931571499008
score 13.211869

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