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Quantifying canine tissue stiffness change patterns using shear-wave elastography: implications for time of death estimation

This study investigates the applicability and reproducibility of shear-wave elastography (SWE) in detecting changes in tissue stiffness of canine carcasses. SWE was performed on six canines by two operators. The target organs were liver, spleen, kidney, and thigh muscles. SWE was performed ante-mort...

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Main Authors: Ong, Wee Kee, Leong, Sook Sam, Azman, Raja Rizal, Md Shah, Mohammad Nazri, Vijayananthan, Anushya, Lau, Seng Fong
Format: Article
Published: Taylor and Francis 2024
Online Access:http://psasir.upm.edu.my/id/eprint/114898/
https://www.tandfonline.com/doi/full/10.1080/00450618.2024.2394414
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spelling my.upm.eprints.1148982025-02-07T04:00:57Z http://psasir.upm.edu.my/id/eprint/114898/ Quantifying canine tissue stiffness change patterns using shear-wave elastography: implications for time of death estimation Ong, Wee Kee Leong, Sook Sam Azman, Raja Rizal Md Shah, Mohammad Nazri Vijayananthan, Anushya Lau, Seng Fong This study investigates the applicability and reproducibility of shear-wave elastography (SWE) in detecting changes in tissue stiffness of canine carcasses. SWE was performed on six canines by two operators. The target organs were liver, spleen, kidney, and thigh muscles. SWE was performed ante-mortem and up to 48-hours post-mortem at specific intervals. The Mann-Whitney U-test and Spearman correlation coefficient showed insignificant correlation between gender and weight with shear-wave velocity (SWV) in ante-mortem scans. The Kruskal-Wallis H-test showed significant differences in SWV for all organs. Intraclass correlation coefficient (ICC) showed excellent correlation for all target organs except for kidneys. Pairwise comparison showed a similar SWV trend for abdominal organs. Accuracy metrics were calculated for determining the post-mortem interval using SWV values. The liver had the highest accuracy (0.69–0.83) across different post-mortem interval thresholds within the cut-off values of ≥2.0 m/s, 1.8–2.0 m/s, <1.8 m/s indicating ≤6 hours post-mortem, 12–18 hours post-mortem and >18 hours post-mortem. The spleen, kidney and thigh muscle demonstrated moderate-to-poor accuracy within the same cut-off parameters. Post-mortem SWV changes in canine solid organs, and soft tissues, particularly the liver, demonstrate a reproducible pattern, which may have value in determining the post-mortem interval. Taylor and Francis 2024-09-01 Article PeerReviewed Ong, Wee Kee and Leong, Sook Sam and Azman, Raja Rizal and Md Shah, Mohammad Nazri and Vijayananthan, Anushya and Lau, Seng Fong (2024) Quantifying canine tissue stiffness change patterns using shear-wave elastography: implications for time of death estimation. Australian Journal of Forensic Sciences. pp. 1-14. ISSN 0045-0618; eISSN: 1834-562X https://www.tandfonline.com/doi/full/10.1080/00450618.2024.2394414 10.1080/00450618.2024.2394414
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
description This study investigates the applicability and reproducibility of shear-wave elastography (SWE) in detecting changes in tissue stiffness of canine carcasses. SWE was performed on six canines by two operators. The target organs were liver, spleen, kidney, and thigh muscles. SWE was performed ante-mortem and up to 48-hours post-mortem at specific intervals. The Mann-Whitney U-test and Spearman correlation coefficient showed insignificant correlation between gender and weight with shear-wave velocity (SWV) in ante-mortem scans. The Kruskal-Wallis H-test showed significant differences in SWV for all organs. Intraclass correlation coefficient (ICC) showed excellent correlation for all target organs except for kidneys. Pairwise comparison showed a similar SWV trend for abdominal organs. Accuracy metrics were calculated for determining the post-mortem interval using SWV values. The liver had the highest accuracy (0.69–0.83) across different post-mortem interval thresholds within the cut-off values of ≥2.0 m/s, 1.8–2.0 m/s, <1.8 m/s indicating ≤6 hours post-mortem, 12–18 hours post-mortem and >18 hours post-mortem. The spleen, kidney and thigh muscle demonstrated moderate-to-poor accuracy within the same cut-off parameters. Post-mortem SWV changes in canine solid organs, and soft tissues, particularly the liver, demonstrate a reproducible pattern, which may have value in determining the post-mortem interval.
format Article
author Ong, Wee Kee
Leong, Sook Sam
Azman, Raja Rizal
Md Shah, Mohammad Nazri
Vijayananthan, Anushya
Lau, Seng Fong
spellingShingle Ong, Wee Kee
Leong, Sook Sam
Azman, Raja Rizal
Md Shah, Mohammad Nazri
Vijayananthan, Anushya
Lau, Seng Fong
Quantifying canine tissue stiffness change patterns using shear-wave elastography: implications for time of death estimation
author_facet Ong, Wee Kee
Leong, Sook Sam
Azman, Raja Rizal
Md Shah, Mohammad Nazri
Vijayananthan, Anushya
Lau, Seng Fong
author_sort Ong, Wee Kee
title Quantifying canine tissue stiffness change patterns using shear-wave elastography: implications for time of death estimation
title_short Quantifying canine tissue stiffness change patterns using shear-wave elastography: implications for time of death estimation
title_full Quantifying canine tissue stiffness change patterns using shear-wave elastography: implications for time of death estimation
title_fullStr Quantifying canine tissue stiffness change patterns using shear-wave elastography: implications for time of death estimation
title_full_unstemmed Quantifying canine tissue stiffness change patterns using shear-wave elastography: implications for time of death estimation
title_sort quantifying canine tissue stiffness change patterns using shear-wave elastography: implications for time of death estimation
publisher Taylor and Francis
publishDate 2024
url http://psasir.upm.edu.my/id/eprint/114898/
https://www.tandfonline.com/doi/full/10.1080/00450618.2024.2394414
_version_ 1823534622595612672
score 13.244413

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