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Edible bird’s nest soup (EBNS) serves as anti-obesity and antilipemic after 6-weeks of supplementation in high-fat diet (HFD)-fed rats

Traditionally, edible bird’s nest (EBN) has been trusted to have several medicinal effects in the Chinese community. One of the beneficial effects of the EBN is that it is a metabolic stimulator. This study was conducted to investigate the effect of EBN soup (EBNS) and EBN extract (EBNE) on obesity,...

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Main Authors: Mohd Noor, Akmal, Abdul Razak, Intan-Shameha, Ajat, Mokrish, Abu Bakar, Md. Zuki, Mansor, Rozaihan, Ideris, Aini
Format: Article
Language:English
English
Published: Penerbit Universiti Kebangsaan Malaysia 2024
Subjects:
Edible Birds' Nests: Research
Cholesterol
Anti-Obesity
Online Access:http://psasir.upm.edu.my/id/eprint/114399/1/114399.pdf
http://psasir.upm.edu.my/id/eprint/114399/
https://www.ukm.my/jsm/pdf_files/SM-PDF-53-11-2024/1.pdf
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spelling my.upm.eprints.1143992025-01-20T01:24:55Z http://psasir.upm.edu.my/id/eprint/114399/ Edible bird’s nest soup (EBNS) serves as anti-obesity and antilipemic after 6-weeks of supplementation in high-fat diet (HFD)-fed rats Mohd Noor, Akmal Abdul Razak, Intan-Shameha Ajat, Mokrish Abu Bakar, Md. Zuki Mansor, Rozaihan Ideris, Aini Traditionally, edible bird’s nest (EBN) has been trusted to have several medicinal effects in the Chinese community. One of the beneficial effects of the EBN is that it is a metabolic stimulator. This study was conducted to investigate the effect of EBN soup (EBNS) and EBN extract (EBNE) on obesity, body fat distribution, blood lipid profile, and cardiogenic indices in high-fat diet-fed rats. Obesity and dyslipidemia in rats were induced with a high-fat diet (HFD) and Triton X-100 (TX100) and supplemented with or without Simvastatin, EBNS, or EBNE for 6-weeks. Final body weight changes and body fat distribution (subcutaneous and visceral fat) were measured. Triglycerides (TAG), total cholesterol (TC), high-density lipoprotein (HDL), low-density lipoprotein (LDL), and very low-density lipoprotein (VLDL) were measured by taking blood from the lateral coccygeal vein. Subsequently, cardiogenic indices were calculated (LDL/HDL ratio (LHR) and atherogenic index (AI)). In general, the EBNS demonstrated an anti-obesity and antilipemic effect after 6 weeks of supplementation. A significant reduction in body fat deposition was also recorded in the EBNS group, including subcutaneous and visceral fat. Bad cholesterol (LDL) was significantly maintained in the normal range, and cardioprotectant cholesterol (HDL) was significantly elevated as good as Simvastatin. EBNS supplementation was also significantly predicted to reduce the risk of cardiovascular diseases and atherosclerosis development in the rat model. Nonetheless, the EBNE group was not exhibiting equivalent effects as documented in the EBNS group after 6 weeks of supplementation. Penerbit Universiti Kebangsaan Malaysia 2024-09-19 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/114399/1/114399.pdf Mohd Noor, Akmal and Abdul Razak, Intan-Shameha and Ajat, Mokrish and Abu Bakar, Md. Zuki and Mansor, Rozaihan and Ideris, Aini (2024) Edible bird’s nest soup (EBNS) serves as anti-obesity and antilipemic after 6-weeks of supplementation in high-fat diet (HFD)-fed rats. Sains Malaysiana, 53 (11). pp. 3545-3553. ISSN 0126-6039 https://www.ukm.my/jsm/pdf_files/SM-PDF-53-11-2024/1.pdf Edible Birds' Nests: Research Cholesterol Anti-Obesity 10.17576/jsm-2024-5311-01 English
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
English
topic Edible Birds' Nests: Research
Cholesterol
Anti-Obesity
spellingShingle Edible Birds' Nests: Research
Cholesterol
Anti-Obesity
Mohd Noor, Akmal
Abdul Razak, Intan-Shameha
Ajat, Mokrish
Abu Bakar, Md. Zuki
Mansor, Rozaihan
Ideris, Aini
Edible bird’s nest soup (EBNS) serves as anti-obesity and antilipemic after 6-weeks of supplementation in high-fat diet (HFD)-fed rats
description Traditionally, edible bird’s nest (EBN) has been trusted to have several medicinal effects in the Chinese community. One of the beneficial effects of the EBN is that it is a metabolic stimulator. This study was conducted to investigate the effect of EBN soup (EBNS) and EBN extract (EBNE) on obesity, body fat distribution, blood lipid profile, and cardiogenic indices in high-fat diet-fed rats. Obesity and dyslipidemia in rats were induced with a high-fat diet (HFD) and Triton X-100 (TX100) and supplemented with or without Simvastatin, EBNS, or EBNE for 6-weeks. Final body weight changes and body fat distribution (subcutaneous and visceral fat) were measured. Triglycerides (TAG), total cholesterol (TC), high-density lipoprotein (HDL), low-density lipoprotein (LDL), and very low-density lipoprotein (VLDL) were measured by taking blood from the lateral coccygeal vein. Subsequently, cardiogenic indices were calculated (LDL/HDL ratio (LHR) and atherogenic index (AI)). In general, the EBNS demonstrated an anti-obesity and antilipemic effect after 6 weeks of supplementation. A significant reduction in body fat deposition was also recorded in the EBNS group, including subcutaneous and visceral fat. Bad cholesterol (LDL) was significantly maintained in the normal range, and cardioprotectant cholesterol (HDL) was significantly elevated as good as Simvastatin. EBNS supplementation was also significantly predicted to reduce the risk of cardiovascular diseases and atherosclerosis development in the rat model. Nonetheless, the EBNE group was not exhibiting equivalent effects as documented in the EBNS group after 6 weeks of supplementation.
format Article
author Mohd Noor, Akmal
Abdul Razak, Intan-Shameha
Ajat, Mokrish
Abu Bakar, Md. Zuki
Mansor, Rozaihan
Ideris, Aini
author_facet Mohd Noor, Akmal
Abdul Razak, Intan-Shameha
Ajat, Mokrish
Abu Bakar, Md. Zuki
Mansor, Rozaihan
Ideris, Aini
author_sort Mohd Noor, Akmal
title Edible bird’s nest soup (EBNS) serves as anti-obesity and antilipemic after 6-weeks of supplementation in high-fat diet (HFD)-fed rats
title_short Edible bird’s nest soup (EBNS) serves as anti-obesity and antilipemic after 6-weeks of supplementation in high-fat diet (HFD)-fed rats
title_full Edible bird’s nest soup (EBNS) serves as anti-obesity and antilipemic after 6-weeks of supplementation in high-fat diet (HFD)-fed rats
title_fullStr Edible bird’s nest soup (EBNS) serves as anti-obesity and antilipemic after 6-weeks of supplementation in high-fat diet (HFD)-fed rats
title_full_unstemmed Edible bird’s nest soup (EBNS) serves as anti-obesity and antilipemic after 6-weeks of supplementation in high-fat diet (HFD)-fed rats
title_sort edible bird’s nest soup (ebns) serves as anti-obesity and antilipemic after 6-weeks of supplementation in high-fat diet (hfd)-fed rats
publisher Penerbit Universiti Kebangsaan Malaysia
publishDate 2024
url http://psasir.upm.edu.my/id/eprint/114399/1/114399.pdf
http://psasir.upm.edu.my/id/eprint/114399/
https://www.ukm.my/jsm/pdf_files/SM-PDF-53-11-2024/1.pdf
_version_ 1823093143075028992
score 13.235362

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